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Mixed Osteosarcoma

MedGen UID:
79014
•Concept ID:
C0279604
•
Neoplastic Process

Definition

A term referring to conventional osteosarcomas which do not have a dominant matrix pattern and contain a mixture of osteoid matrix in combination with chondroid matrix and/or collagen fibers. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed Osteosarcoma

Professional guidelines

PubMed

Imaging diagnosis and differential diagnosis of extraskeletal osteosarcoma.
Wang XC, Zhang L, Lin JB, Huang XY, Liang JH, Zhong JP, Peng JD, Zhong JY
BMC Cancer 2024 Jan 2;24(1):11. doi: 10.1186/s12885-023-11731-3. PMID: 38166700Free PMC Article
A Nanodrug Consisting Of Doxorubicin And Exosome Derived From Mesenchymal Stem Cells For Osteosarcoma Treatment In Vitro.
Wei H, Chen J, Wang S, Fu F, Zhu X, Wu C, Liu Z, Zhong G, Lin J
Int J Nanomedicine 2019;14:8603-8610. Epub 2019 Nov 1 doi: 10.2147/IJN.S218988. PMID: 31802872Free PMC Article
Osteosarcoma: a multidisciplinary approach to diagnosis and treatment.
Wittig JC, Bickels J, Priebat D, Jelinek J, Kellar-Graney K, Shmookler B, Malawer MM
Am Fam Physician 2002 Mar 15;65(6):1123-32. PMID: 11925089

Recent clinical studies

Etiology

SATB2 Expression Is Sensitive but Not Specific for Osteosarcomatous Components of Gynecologic Tract Carcinosarcomas: A Clinicopathologic Study of 60 Cases.
Sangoi AR, Kshirsagar M, Horvai AE, Roma AA
Int J Gynecol Pathol 2017 Mar;36(2):140-145. doi: 10.1097/PGP.0000000000000301. PMID: 27294605

Diagnosis

SATB2 Expression Is Sensitive but Not Specific for Osteosarcomatous Components of Gynecologic Tract Carcinosarcomas: A Clinicopathologic Study of 60 Cases.
Sangoi AR, Kshirsagar M, Horvai AE, Roma AA
Int J Gynecol Pathol 2017 Mar;36(2):140-145. doi: 10.1097/PGP.0000000000000301. PMID: 27294605

Prognosis

SATB2 Expression Is Sensitive but Not Specific for Osteosarcomatous Components of Gynecologic Tract Carcinosarcomas: A Clinicopathologic Study of 60 Cases.
Sangoi AR, Kshirsagar M, Horvai AE, Roma AA
Int J Gynecol Pathol 2017 Mar;36(2):140-145. doi: 10.1097/PGP.0000000000000301. PMID: 27294605

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