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Epstein-Barr virus-associated malignant lymphoproliferative disorder

MedGen UID:
797800
Concept ID:
C2363744
Disease or Syndrome
Synonyms: EBV-associated lymphoproliferative disorder; EBV-Related Lymphoproliferative Disorder; Epstein-Barr Virus-Associated Lymphoproliferative Disorder; Epstein-Barr Virus-Related Lymphoproliferative Disorder
 
Monarch Initiative: MONDO:0017343
Orphanet: ORPHA289644

Definition

A lymphoproliferative disorder associated with Epstein-Barr virus. This category includes, but is not limited to, Burkitt lymphoma, classic Hodgkin lymphoma, and lymphomas arising in immunocompromised individuals. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpstein-Barr virus-associated malignant lymphoproliferative disorder
Follow this link to review classifications for Epstein-Barr virus-associated malignant lymphoproliferative disorder in Orphanet.

Professional guidelines

PubMed

Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Crombie J, LaCasce A
Blood 2021 Feb 11;137(6):743-750. doi: 10.1182/blood.2019004099. PMID: 33171490
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article

Recent clinical studies

Etiology

Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Thandra KC, Barsouk A, Saginala K, Padala SA, Barsouk A, Rawla P
Med Sci (Basel) 2021 Jan 30;9(1) doi: 10.3390/medsci9010005. PMID: 33573146Free PMC Article
Hue SS, Oon ML, Wang S, Tan SY, Ng SB
Pathology 2020 Jan;52(1):111-127. Epub 2019 Nov 22 doi: 10.1016/j.pathol.2019.09.011. PMID: 31767131
Fugl A, Andersen CL
BMC Fam Pract 2019 May 14;20(1):62. doi: 10.1186/s12875-019-0954-3. PMID: 31088382Free PMC Article

Diagnosis

Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Thandra KC, Barsouk A, Saginala K, Padala SA, Barsouk A, Rawla P
Med Sci (Basel) 2021 Jan 30;9(1) doi: 10.3390/medsci9010005. PMID: 33573146Free PMC Article
Hue SS, Oon ML, Wang S, Tan SY, Ng SB
Pathology 2020 Jan;52(1):111-127. Epub 2019 Nov 22 doi: 10.1016/j.pathol.2019.09.011. PMID: 31767131
Borie R, Wislez M, Antoine M, Cadranel J
Respiration 2017;94(2):157-175. Epub 2017 Jun 14 doi: 10.1159/000477740. PMID: 28609772

Therapy

Martinez OM
Pediatr Nephrol 2020 Jul;35(7):1173-1181. Epub 2019 Jun 25 doi: 10.1007/s00467-019-04284-w. PMID: 31240394
Lilly AJ, Fedoriw Y
Surg Pathol Clin 2019 Sep;12(3):771-782. Epub 2019 May 17 doi: 10.1016/j.path.2019.03.005. PMID: 31352987
Hui KF, Tam KP, Chiang AKS
Viruses 2017 Nov 21;9(11) doi: 10.3390/v9110352. PMID: 29160853Free PMC Article
Wagner-Johnston ND, Ambinder RF
Curr Hematol Malig Rep 2007 Oct;2(4):249-54. doi: 10.1007/s11899-007-0034-y. PMID: 20425377
Ahmed N, Heslop HE
Curr Opin Hematol 2006 Jul;13(4):254-9. doi: 10.1097/01.moh.0000231423.38525.fe. PMID: 16755222

Prognosis

Bednarska K, Chowdhury R, Tobin JWD, Swain F, Keane C, Boyle S, Khanna R, Gandhi MK
Br J Haematol 2024 Feb;204(2):415-433. Epub 2023 Dec 28 doi: 10.1111/bjh.19255. PMID: 38155519
Quintanilla-Martinez L, Swerdlow SH, Tousseyn T, Barrionuevo C, Nakamura S, Jaffe ES
Virchows Arch 2023 Jan;482(1):227-244. Epub 2022 Oct 11 doi: 10.1007/s00428-022-03414-4. PMID: 36216980Free PMC Article
Zhang H, Zhao S, Cao Z
Front Immunol 2022;13:1001055. Epub 2022 Oct 28 doi: 10.3389/fimmu.2022.1001055. PMID: 36389673Free PMC Article
Borie R, Wislez M, Antoine M, Cadranel J
Respiration 2017;94(2):157-175. Epub 2017 Jun 14 doi: 10.1159/000477740. PMID: 28609772
Goodlad JR
Surg Pathol Clin 2017 Jun;10(2):429-453. Epub 2017 Mar 18 doi: 10.1016/j.path.2017.01.001. PMID: 28477890

Clinical prediction guides

Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
Wong Y, Meehan MT, Burrows SR, Doolan DL, Miles JJ
J Cancer Res Clin Oncol 2022 Jan;148(1):31-46. Epub 2021 Oct 27 doi: 10.1007/s00432-021-03824-y. PMID: 34705104Free PMC Article
Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H
Nat Microbiol 2019 Mar;4(3):404-413. Epub 2019 Jan 21 doi: 10.1038/s41564-018-0334-0. PMID: 30664667
Vockerodt M, Yap LF, Shannon-Lowe C, Curley H, Wei W, Vrzalikova K, Murray PG
J Pathol 2015 Jan;235(2):312-22. doi: 10.1002/path.4459. PMID: 25294567
Gandhi MK
Expert Rev Anti Infect Ther 2006 Feb;4(1):77-89. doi: 10.1586/14787210.4.1.77. PMID: 16441211

Recent systematic reviews

Honar N, Shahramian I, Imanieh MH, Ataollahi M, Tahani M, Rakhshaninasab S, Javadifar A
Hum Antibodies 2022;30(4):183-194. doi: 10.3233/HAB-220016. PMID: 37005883
Mullen CJR, Volesky KD, Greenwald ZR, El-Zein M, Franco EL
Cancer Epidemiol Biomarkers Prev 2021 Dec;30(12):2167-2175. Epub 2021 Sep 20 doi: 10.1158/1055-9965.EPI-21-0548. PMID: 34548328
Bakkalci D, Jia Y, Winter JR, Lewis JE, Taylor GS, Stagg HR
J Glob Health 2020 Jun;10(1):010405. doi: 10.7189/jogh.10.010405. PMID: 32257153Free PMC Article
Herber M, Mertz P, Dieudonné Y, Guffroy B, Jung S, Gies V, Korganow AS, Guffroy A
Leuk Lymphoma 2020 Feb;61(2):274-284. Epub 2019 Oct 3 doi: 10.1080/10428194.2019.1672056. PMID: 31580160
Masson P, Henderson L, Chapman JR, Craig JC, Webster AC
Cochrane Database Syst Rev 2014 Nov 24;2014(11):CD010699. doi: 10.1002/14651858.CD010699.pub2. PMID: 25416857Free PMC Article

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