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Congenital anomaly of the great arteries

MedGen UID:
798768
•Concept ID:
C0948632
•
Congenital Abnormality
Synonyms: Congenital anomaly of great vessel; congenital anomaly of the great arteries; Congenital aorta, aortic arch or pulmonary arteries anomaly; congenital aorta, aortic arch or pulmonary arteries anomaly
SNOMED CT: Congenital anomaly of great vessel (762250009)
 
Monarch Initiative: MONDO:0020292
Orphanet: ORPHA98724

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCongenital anomaly of the great arteries
Follow this link to review classifications for Congenital anomaly of the great arteries in Orphanet.

Professional guidelines

PubMed

Management of congenitally corrected transposition from fetal diagnosis to adulthood.
Kowalik E
Expert Rev Cardiovasc Ther 2023 Jun;21(6):389-396. Epub 2023 May 9 doi: 10.1080/14779072.2023.2211264. PMID: 37143366
Assessment and management of heart failure in the systemic right ventricle.
Carazo M, Andrade L, Kim Y, Wilson W, Wu FM
Heart Fail Rev 2020 Jul;25(4):609-621. doi: 10.1007/s10741-020-09914-2. PMID: 31970551
Management of the Adult Patient With Congenitally Corrected Transposition: Challenges and Uncertainties.
Connolly HM, Miranda WR, Egbe AC, Warnes CA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2019;22:61-65. doi: 10.1053/j.pcsu.2019.02.006. PMID: 31027566

Recent clinical studies

Etiology

Transpositions of the great arteries versus aortic dextropositions. A review of some embryogenetic and morphological aspects.
Restivo A, di Gioia C, Marino B, Putotto C
Anat Rec (Hoboken) 2023 Mar;306(3):502-514. Epub 2022 Dec 9 doi: 10.1002/ar.25129. PMID: 36426596
Outcome of Pregnancy in Women With D-Transposition of the Great Arteries: A Systematic Review.
Pizula J, Devera J, Ng TMH, Yeung SL, Thangathurai J, Herrick N, Chatfield AJ, Mehra A, Elkayam U
J Am Heart Assoc 2022 Dec 6;11(23):e026862. Epub 2022 Nov 29 doi: 10.1161/JAHA.122.026862. PMID: 36444833Free PMC Article
Techniques and pitfalls of coronary arterial reimplantation in anatomical correction of transposition.
Chowdhury UK, Anderson RH, Spicer DE, Sankhyan LK, George N, Pandey NN, Goja S, Chandhirasekar B
J Card Surg 2022 Nov;37(11):3813-3824. Epub 2022 Sep 18 doi: 10.1111/jocs.16889. PMID: 36116113
CT of transposition of the great arteries in adults.
Panayiotou A, Thorne S, Hudsmith LE, Holloway B
Clin Radiol 2022 Apr;77(4):e261-e268. Epub 2021 Dec 31 doi: 10.1016/j.crad.2021.12.006. PMID: 34980460
Transposition of the great arteries.
Squarcia U, Macchi C
Curr Opin Pediatr 2011 Oct;23(5):518-22. doi: 10.1097/MOP.0b013e32834aa551. PMID: 21849902

Diagnosis

Management of congenitally corrected transposition from fetal diagnosis to adulthood.
Kowalik E
Expert Rev Cardiovasc Ther 2023 Jun;21(6):389-396. Epub 2023 May 9 doi: 10.1080/14779072.2023.2211264. PMID: 37143366
Deep Phenotypic Analysis for Transposition of the Great Arteries and Prognosis Implication.
Shen H, He Q, Shao X, Li S, Zhou Z
J Am Heart Assoc 2022 Feb;11(3):e023181. Epub 2022 Jan 8 doi: 10.1161/JAHA.121.023181. PMID: 35001652Free PMC Article
CT evaluation of unrepaired/incidental congenital cardiovascular diseases in adults.
Bedayat A, Jalili MH, Hassani C, Chalian H, Reuhm S, Moriarty J
Diagn Interv Imaging 2021 Apr;102(4):213-224. Epub 2020 Oct 21 doi: 10.1016/j.diii.2020.09.011. PMID: 34102129
Dual-source computed tomography coronary artery imaging in children.
Secinaro A, Curione D, Mortensen KH, Santangelo TP, Ciancarella P, Napolitano C, Del Pasqua A, Taylor AM, Ciliberti P
Pediatr Radiol 2019 Dec;49(13):1823-1839. Epub 2019 Aug 22 doi: 10.1007/s00247-019-04494-2. PMID: 31440884
Transposition of the great arteries.
Squarcia U, Macchi C
Curr Opin Pediatr 2011 Oct;23(5):518-22. doi: 10.1097/MOP.0b013e32834aa551. PMID: 21849902

Therapy

Management of the Adult with Arterial Switch.
Breinholt JP, John S
Methodist Debakey Cardiovasc J 2019 Apr-Jun;15(2):133-137. doi: 10.14797/mdcj-15-2-133. PMID: 31384376Free PMC Article
Contemporary management and outcomes in congenitally corrected transposition of the great arteries.
Kutty S, Danford DA, Diller GP, Tutarel O
Heart 2018 Jul;104(14):1148-1155. Epub 2018 Jan 11 doi: 10.1136/heartjnl-2016-311032. PMID: 29326110
L-Transposition of the Great Arteries.
Ravishankar C
Pediatr Crit Care Med 2016 Aug;17(8 Suppl 1):S344-6. doi: 10.1097/PCC.0000000000000825. PMID: 27490621
Transposition of the Great Arteries and Common Variants.
Wernovsky G
Pediatr Crit Care Med 2016 Aug;17(8 Suppl 1):S337-43. doi: 10.1097/PCC.0000000000000819. PMID: 27490620
Anesthetic Considerations and Management of Transposition of the Great Arteries.
Latham GJ, Joffe DC, Eisses MJ, Richards MJ, Geiduschek JM
Semin Cardiothorac Vasc Anesth 2015 Sep;19(3):233-42. Epub 2015 Apr 21 doi: 10.1177/1089253215581852. PMID: 25900898

Prognosis

Growth of the Neo-Aortic Root and Prognosis of Transposition of the Great Arteries.
Sengupta A, Carreon CK, Gauvreau K, Lee JM, Sanders SP, Colan SD, Del Nido PJ, Mayer JE Jr, Nathan M
J Am Coll Cardiol 2024 Jan 30;83(4):516-527. Epub 2023 Nov 6 doi: 10.1016/j.jacc.2023.10.023. PMID: 37939977
Techniques and pitfalls of coronary arterial reimplantation in anatomical correction of transposition.
Chowdhury UK, Anderson RH, Spicer DE, Sankhyan LK, George N, Pandey NN, Goja S, Chandhirasekar B
J Card Surg 2022 Nov;37(11):3813-3824. Epub 2022 Sep 18 doi: 10.1111/jocs.16889. PMID: 36116113
Long-Term Outcomes After Atrial Switch Operation for Transposition of the Great Arteries.
Broberg CS, van Dissel A, Minnier J, Aboulhosn J, Kauling RM, Ginde S, Krieger EV, Rodriguez F 3rd, Gupta T, Shah S, John AS, Cotts T, Kay WA, Kuo M, Dwight C, Woods P, Nicolarsen J, Sarubbi B, Fusco F, Antonova P, Fernandes S, Grewal J, Cramer J, Khairy P, Gallego P, O'Donnell C, Hannah J, Dellborg M, Rodriguez-Monserrate CP, Muhll IV, Pylypchuk S, Magalski A, Han F, Lubert AM, Kay J, Yeung E, Roos-Hesselink J, Baker D, Celermajer DS, Burchill LJ, Wilson WM, Wong J, Kutty S, Opotowsky AR
J Am Coll Cardiol 2022 Sep 6;80(10):951-963. doi: 10.1016/j.jacc.2022.06.020. PMID: 36049802
Deep Phenotypic Analysis for Transposition of the Great Arteries and Prognosis Implication.
Shen H, He Q, Shao X, Li S, Zhou Z
J Am Heart Assoc 2022 Feb;11(3):e023181. Epub 2022 Jan 8 doi: 10.1161/JAHA.121.023181. PMID: 35001652Free PMC Article
Arterial switch.
Planche C, Lacour-Gayet F, Serraf A
Pediatr Cardiol 1998 Jul-Aug;19(4):297-307. doi: 10.1007/s002469900313. PMID: 9636253

Clinical prediction guides

Growth of the Neo-Aortic Root and Prognosis of Transposition of the Great Arteries.
Sengupta A, Carreon CK, Gauvreau K, Lee JM, Sanders SP, Colan SD, Del Nido PJ, Mayer JE Jr, Nathan M
J Am Coll Cardiol 2024 Jan 30;83(4):516-527. Epub 2023 Nov 6 doi: 10.1016/j.jacc.2023.10.023. PMID: 37939977
Clinical and genetic approach in the characterization of newborns with anorectal malformation.
Schierz IAM, Piro E, Giuffrè M, Pinello G, Angelini A, Antona V, Cimador M, Corsello G
J Matern Fetal Neonatal Med 2022 Dec;35(23):4513-4520. Epub 2020 Dec 1 doi: 10.1080/14767058.2020.1854213. PMID: 36062518
Long-Term Outcomes After Atrial Switch Operation for Transposition of the Great Arteries.
Broberg CS, van Dissel A, Minnier J, Aboulhosn J, Kauling RM, Ginde S, Krieger EV, Rodriguez F 3rd, Gupta T, Shah S, John AS, Cotts T, Kay WA, Kuo M, Dwight C, Woods P, Nicolarsen J, Sarubbi B, Fusco F, Antonova P, Fernandes S, Grewal J, Cramer J, Khairy P, Gallego P, O'Donnell C, Hannah J, Dellborg M, Rodriguez-Monserrate CP, Muhll IV, Pylypchuk S, Magalski A, Han F, Lubert AM, Kay J, Yeung E, Roos-Hesselink J, Baker D, Celermajer DS, Burchill LJ, Wilson WM, Wong J, Kutty S, Opotowsky AR
J Am Coll Cardiol 2022 Sep 6;80(10):951-963. doi: 10.1016/j.jacc.2022.06.020. PMID: 36049802
Prediction of neonatal coarctation of the aorta at fetal echocardiography: a scoring system.
Contro E, Cattani L, Balducci A, Prandstraller D, Perolo A, Larcher L, Reggiani MLB, Farina A, Donti A, Gargiulo GD, Pilu G
J Matern Fetal Neonatal Med 2022 Nov;35(22):4299-4305. Epub 2020 Nov 17 doi: 10.1080/14767058.2020.1849109. PMID: 33203263
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326

Recent systematic reviews

Long-term outcome of patients with transposition of the great arteries and a systemic right ventricle: A systematic review and meta-analysis.
Ansari Ramandi MM, Yarmohammadi H, Gareb B, Voors AA, van Melle JP
Int J Cardiol 2023 Oct 15;389:131159. Epub 2023 Jul 9 doi: 10.1016/j.ijcard.2023.131159. PMID: 37433408
The association between maternal air pollution exposure and the incidence of congenital heart diseases in children: A systematic review and meta-analysis.
Wan X, Wei S, Wang Y, Jiang J, Lian X, Zou Z, Li J
Sci Total Environ 2023 Sep 20;892:164431. Epub 2023 Jun 1 doi: 10.1016/j.scitotenv.2023.164431. PMID: 37268121
Outcome of Pregnancy in Women With D-Transposition of the Great Arteries: A Systematic Review.
Pizula J, Devera J, Ng TMH, Yeung SL, Thangathurai J, Herrick N, Chatfield AJ, Mehra A, Elkayam U
J Am Heart Assoc 2022 Dec 6;11(23):e026862. Epub 2022 Nov 29 doi: 10.1161/JAHA.122.026862. PMID: 36444833Free PMC Article
Arterial Stiffness in Congenital Heart Disease.
Sandhu K, Pepe S, Smolich JJ, Cheung MMH, Mynard JP
Heart Lung Circ 2021 Nov;30(11):1602-1612. Epub 2021 Aug 20 doi: 10.1016/j.hlc.2021.07.018. PMID: 34420886
Congenital Heart Defects and Measures of Prenatal Brain Growth: A Systematic Review.
Hansen T, Henriksen TB, Bach CC, Matthiesen NB
Pediatr Neurol 2017 Jul;72:7-18.e1. Epub 2017 Apr 1 doi: 10.1016/j.pediatrneurol.2017.03.014. PMID: 28549654

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