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Anthrax infection

MedGen UID:
8110
Concept ID:
C0003175
Disease or Syndrome
Synonyms: Anthrax; Black Baine; Malignant edema; Malignant pustule; Ragpicker's disease; Siberian Plague; Wool sorter's disease
SNOMED CT: Anthrax (409498004); Milzbrand (409498004); Infection due to Bacillus anthracis (409498004); Splenic fever (409498004); Charbon (409498004)
 
Monarch Initiative: MONDO:0005119

Definition

An infection caused by Bacillus anthracis bacteria. It may affect the lungs, gastrointestinal tract, or skin. Patients with lung infection present with fever, headaches, cough, chest pain and shortness of breath. Patients with gastrointestinal infection present with nausea, vomiting and bloody diarrhea. Patients with skin infection develop blisters and ulcers. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnthrax infection

Professional guidelines

PubMed

Hesse EM, Godfred-Cato S, Bower WA
Clin Infect Dis 2022 Oct 17;75(Suppl 3):S432-S440. doi: 10.1093/cid/ciac532. PMID: 36251559Free PMC Article
Vietri NJ
Curr Opin Infect Dis 2018 Jun;31(3):257-262. doi: 10.1097/QCO.0000000000000446. PMID: 29570493
Brook I
Int J Antimicrob Agents 2002 Nov;20(5):320-5. doi: 10.1016/s0924-8579(02)00200-5. PMID: 12431866

Recent clinical studies

Etiology

Sarker MSA, Shahid MAH, Rahman MB, Nazir KHMNH
J Infect Public Health 2023 Dec;16 Suppl 1:141-152. Epub 2023 Oct 31 doi: 10.1016/j.jiph.2023.10.024. PMID: 37953112
Gulseren D, Süzük-Yıldız S, Çelebi B, Kılıç S
Cutan Ocul Toxicol 2017 Sep;36(3):289-293. Epub 2017 Feb 2 doi: 10.1080/15569527.2017.1281288. PMID: 28076993
Hussain SS, Tyroch AH, Mukherjee D
Cardiovasc Hematol Agents Med Chem 2017;14(2):76-81. doi: 10.2174/1871525714666160524144359. PMID: 27215215
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364
Inglesby TV, O'Toole T, Henderson DA, Bartlett JG, Ascher MS, Eitzen E, Friedlander AM, Gerberding J, Hauer J, Hughes J, McDade J, Osterholm MT, Parker G, Perl TM, Russell PK, Tonat K; Working Group on Civilian Biodefense
JAMA 2002 May 1;287(17):2236-52. doi: 10.1001/jama.287.17.2236. PMID: 11980524

Diagnosis

Zasada AA
Adv Clin Exp Med 2018 Apr;27(4):553-558. doi: 10.17219/acem/68380. PMID: 29533547
Owen JL, Yang T, Mohamadzadeh M
Trends Mol Med 2015 Mar;21(3):154-63. Epub 2014 Dec 19 doi: 10.1016/j.molmed.2014.12.003. PMID: 25577136Free PMC Article
Sweeney DA, Hicks CW, Cui X, Li Y, Eichacker PQ
Am J Respir Crit Care Med 2011 Dec 15;184(12):1333-41. Epub 2011 Aug 18 doi: 10.1164/rccm.201102-0209CI. PMID: 21852539Free PMC Article
Wallin A, Luksiene Z, Zagminas K, Surkiene G
Medicina (Kaunas) 2007;43(4):278-84. PMID: 17485954
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364

Therapy

Vietri NJ
Curr Opin Infect Dis 2018 Jun;31(3):257-262. doi: 10.1097/QCO.0000000000000446. PMID: 29570493
Zasada AA
Adv Clin Exp Med 2018 Apr;27(4):553-558. doi: 10.17219/acem/68380. PMID: 29533547
Kumar BV, Malik S, Grandhi P, Dayam R, Sarma JA
Curr Top Med Chem 2014;14(17):1977-89. doi: 10.2174/1568026614666140929120231. PMID: 25262802
Sweeney DA, Hicks CW, Cui X, Li Y, Eichacker PQ
Am J Respir Crit Care Med 2011 Dec 15;184(12):1333-41. Epub 2011 Aug 18 doi: 10.1164/rccm.201102-0209CI. PMID: 21852539Free PMC Article
Grabenstein JD
Clin Infect Dis 2008 Jan 1;46(1):129-36. doi: 10.1086/523578. PMID: 18171228

Prognosis

Vietri NJ
Curr Opin Infect Dis 2018 Jun;31(3):257-262. doi: 10.1097/QCO.0000000000000446. PMID: 29570493
Liu S, Moayeri M, Leppla SH
Trends Microbiol 2014 Jun;22(6):317-25. Epub 2014 Mar 27 doi: 10.1016/j.tim.2014.02.012. PMID: 24684968Free PMC Article
Ascough S, Ingram RJ, Altmann DM
Toxins (Basel) 2012 Oct;4(10):878-99. Epub 2012 Oct 19 doi: 10.3390/toxins4100878. PMID: 23162703Free PMC Article
Bravata DM, Holty JE, Wang E, Lewis R, Wise PH, McDonald KM, Owens DK
Arch Pediatr Adolesc Med 2007 Sep;161(9):896-905. doi: 10.1001/archpedi.161.9.896. PMID: 17768291
Lanska DJ
Neurology 2002 Aug 13;59(3):327-34. doi: 10.1212/wnl.59.3.327. PMID: 12177364

Clinical prediction guides

Metzger D, Miller K, Lyon W, Migliozzi R, Pangburn HA, Saldanha R
ACS Synth Biol 2022 Nov 18;11(11):3657-3668. Epub 2022 Nov 1 doi: 10.1021/acssynbio.2c00214. PMID: 36318971
Zhang E, Zhang H, He J, Li W, Wei J
BMC Infect Dis 2020 Feb 14;20(1):140. doi: 10.1186/s12879-020-4867-5. PMID: 32059712Free PMC Article
Bai JP, Sakellaropoulos T, Alexopoulos LG
Toxins (Basel) 2017 Mar 10;9(3) doi: 10.3390/toxins9030099. PMID: 28287432Free PMC Article
Ascough S, Ingram RJ, Altmann DM
Toxins (Basel) 2012 Oct;4(10):878-99. Epub 2012 Oct 19 doi: 10.3390/toxins4100878. PMID: 23162703Free PMC Article
Bravata DM, Holty JE, Wang E, Lewis R, Wise PH, McDonald KM, Owens DK
Arch Pediatr Adolesc Med 2007 Sep;161(9):896-905. doi: 10.1001/archpedi.161.9.896. PMID: 17768291

Recent systematic reviews

Hesse EM, Godfred-Cato S, Bower WA
Clin Infect Dis 2022 Oct 17;75(Suppl 3):S432-S440. doi: 10.1093/cid/ciac532. PMID: 36251559Free PMC Article
Bravata DM, Holty JE, Wang E, Lewis R, Wise PH, McDonald KM, Owens DK
Arch Pediatr Adolesc Med 2007 Sep;161(9):896-905. doi: 10.1001/archpedi.161.9.896. PMID: 17768291
Holty JE, Kim RY, Bravata DM
Ann Emerg Med 2006 Aug;48(2):200-11. Epub 2006 Feb 21 doi: 10.1016/j.annemergmed.2005.11.035. PMID: 16857469

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