U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bone Marrow Fibrosis

MedGen UID:
811048
•Concept ID:
C2355575
•
Finding
Synonym: Bone marrow fibrosis

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone Marrow Fibrosis

Professional guidelines

PubMed

Anemia in myelofibrosis: Current and emerging treatment options.
Passamonti F, Harrison CN, Mesa RA, Kiladjian JJ, Vannucchi AM, Verstovsek S
Crit Rev Oncol Hematol 2022 Dec;180:103862. Epub 2022 Nov 1 doi: 10.1016/j.critrevonc.2022.103862. PMID: 36332787
Next Generation Therapeutics for the Treatment of Myelofibrosis.
Tremblay D, Mascarenhas J
Cells 2021 Apr 27;10(5) doi: 10.3390/cells10051034. PMID: 33925695Free PMC Article
Management of myelofibrosis after ruxolitinib failure.
Harrison CN, Schaap N, Mesa RA
Ann Hematol 2020 Jun;99(6):1177-1191. Epub 2020 Mar 20 doi: 10.1007/s00277-020-04002-9. PMID: 32198525Free PMC Article

Recent clinical studies

Etiology

Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update.
Jain AG, Zhang L, Bennett JM, Komrokji R
Ann Lab Med 2022 May 1;42(3):299-305. doi: 10.3343/alm.2022.42.3.299. PMID: 34907099Free PMC Article
Progression of Myeloproliferative Neoplasms (MPN): Diagnostic and Therapeutic Perspectives.
Baumeister J, Chatain N, Sofias AM, Lammers T, Koschmieder S
Cells 2021 Dec 16;10(12) doi: 10.3390/cells10123551. PMID: 34944059Free PMC Article
Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms.
Fisher DAC, Fowles JS, Zhou A, Oh ST
Front Immunol 2021;12:683401. Epub 2021 Jun 1 doi: 10.3389/fimmu.2021.683401. PMID: 34140953Free PMC Article
Management of myelofibrosis after ruxolitinib failure.
Harrison CN, Schaap N, Mesa RA
Ann Hematol 2020 Jun;99(6):1177-1191. Epub 2020 Mar 20 doi: 10.1007/s00277-020-04002-9. PMID: 32198525Free PMC Article
Ruxolitinib.
Ajayi S, Becker H, Reinhardt H, Engelhardt M, Zeiser R, von Bubnoff N, Wäsch R
Recent Results Cancer Res 2018;212:119-132. doi: 10.1007/978-3-319-91439-8_6. PMID: 30069628

Diagnosis

Myelofibrosis.
Passamonti F, Mora B
Blood 2023 Apr 20;141(16):1954-1970. doi: 10.1182/blood.2022017423. PMID: 36416738
Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update.
Jain AG, Zhang L, Bennett JM, Komrokji R
Ann Lab Med 2022 May 1;42(3):299-305. doi: 10.3343/alm.2022.42.3.299. PMID: 34907099Free PMC Article
Progression of Myeloproliferative Neoplasms (MPN): Diagnostic and Therapeutic Perspectives.
Baumeister J, Chatain N, Sofias AM, Lammers T, Koschmieder S
Cells 2021 Dec 16;10(12) doi: 10.3390/cells10123551. PMID: 34944059Free PMC Article
Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms.
Fisher DAC, Fowles JS, Zhou A, Oh ST
Front Immunol 2021;12:683401. Epub 2021 Jun 1 doi: 10.3389/fimmu.2021.683401. PMID: 34140953Free PMC Article
Management of myelofibrosis after ruxolitinib failure.
Harrison CN, Schaap N, Mesa RA
Ann Hematol 2020 Jun;99(6):1177-1191. Epub 2020 Mar 20 doi: 10.1007/s00277-020-04002-9. PMID: 32198525Free PMC Article

Therapy

Myelofibrosis.
Passamonti F, Mora B
Blood 2023 Apr 20;141(16):1954-1970. doi: 10.1182/blood.2022017423. PMID: 36416738
Anemia in myelofibrosis: Current and emerging treatment options.
Passamonti F, Harrison CN, Mesa RA, Kiladjian JJ, Vannucchi AM, Verstovsek S
Crit Rev Oncol Hematol 2022 Dec;180:103862. Epub 2022 Nov 1 doi: 10.1016/j.critrevonc.2022.103862. PMID: 36332787
Next Generation Therapeutics for the Treatment of Myelofibrosis.
Tremblay D, Mascarenhas J
Cells 2021 Apr 27;10(5) doi: 10.3390/cells10051034. PMID: 33925695Free PMC Article
Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis.
Talpaz M, Kiladjian JJ
Leukemia 2021 Jan;35(1):1-17. Epub 2020 Jul 9 doi: 10.1038/s41375-020-0954-2. PMID: 32647323Free PMC Article
Management of myelofibrosis after ruxolitinib failure.
Harrison CN, Schaap N, Mesa RA
Ann Hematol 2020 Jun;99(6):1177-1191. Epub 2020 Mar 20 doi: 10.1007/s00277-020-04002-9. PMID: 32198525Free PMC Article

Prognosis

Myelofibrosis.
Passamonti F, Mora B
Blood 2023 Apr 20;141(16):1954-1970. doi: 10.1182/blood.2022017423. PMID: 36416738
Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update.
Jain AG, Zhang L, Bennett JM, Komrokji R
Ann Lab Med 2022 May 1;42(3):299-305. doi: 10.3343/alm.2022.42.3.299. PMID: 34907099Free PMC Article
Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms.
Fisher DAC, Fowles JS, Zhou A, Oh ST
Front Immunol 2021;12:683401. Epub 2021 Jun 1 doi: 10.3389/fimmu.2021.683401. PMID: 34140953Free PMC Article
Accelerated Phase of Myeloproliferative Neoplasms.
Shahin OA, Chifotides HT, Bose P, Masarova L, Verstovsek S
Acta Haematol 2021;144(5):484-499. Epub 2021 Apr 21 doi: 10.1159/000512929. PMID: 33882481Free PMC Article
Management of myelofibrosis after ruxolitinib failure.
Harrison CN, Schaap N, Mesa RA
Ann Hematol 2020 Jun;99(6):1177-1191. Epub 2020 Mar 20 doi: 10.1007/s00277-020-04002-9. PMID: 32198525Free PMC Article

Clinical prediction guides

Myelofibrosis.
Passamonti F, Mora B
Blood 2023 Apr 20;141(16):1954-1970. doi: 10.1182/blood.2022017423. PMID: 36416738
Addition of Navitoclax to Ongoing Ruxolitinib Therapy for Patients With Myelofibrosis With Progression or Suboptimal Response: Phase II Safety and Efficacy.
Harrison CN, Garcia JS, Somervaille TCP, Foran JM, Verstovsek S, Jamieson C, Mesa R, Ritchie EK, Tantravahi SK, Vachhani P, O'Connell CL, Komrokji RS, Harb J, Hutti JE, Holes L, Masud AA, Nuthalapati S, Potluri J, Pemmaraju N
J Clin Oncol 2022 May 20;40(15):1671-1680. Epub 2022 Feb 18 doi: 10.1200/JCO.21.02188. PMID: 35180010Free PMC Article
Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update.
Jain AG, Zhang L, Bennett JM, Komrokji R
Ann Lab Med 2022 May 1;42(3):299-305. doi: 10.3343/alm.2022.42.3.299. PMID: 34907099Free PMC Article
Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms.
Fisher DAC, Fowles JS, Zhou A, Oh ST
Front Immunol 2021;12:683401. Epub 2021 Jun 1 doi: 10.3389/fimmu.2021.683401. PMID: 34140953Free PMC Article
Accelerated Phase of Myeloproliferative Neoplasms.
Shahin OA, Chifotides HT, Bose P, Masarova L, Verstovsek S
Acta Haematol 2021;144(5):484-499. Epub 2021 Apr 21 doi: 10.1159/000512929. PMID: 33882481Free PMC Article

Recent systematic reviews

Osteolytic bone lesions in patients with primary myelofibrosis: A systematic review.
Battukh N, Ali E, Yassin M
Acta Biomed 2022 Jan 19;92(6):e2021478. doi: 10.23750/abm.v92i6.12350. PMID: 35075062Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...