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Skin cancer susceptibility

MedGen UID:
812900
•Concept ID:
C3806570
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin cancer susceptibility

Professional guidelines

PubMed

Molecular Pathology of Skin Melanoma: Epidemiology, Differential Diagnostics, Prognosis and Therapy Prediction.
Tímár J, Ladányi A
Int J Mol Sci 2022 May 11;23(10) doi: 10.3390/ijms23105384. PMID: 35628196Free PMC Article
Update in the Management of Basal Cell Carcinoma.
Basset-Seguin N, Herms F
Acta Derm Venereol 2020 Jun 3;100(11):adv00140. doi: 10.2340/00015555-3495. PMID: 32346750Free PMC Article
Albinism: epidemiology, genetics, cutaneous characterization, psychosocial factors.
Marçon CR, Maia M
An Bras Dermatol 2019 Sep-Oct;94(5):503-520. Epub 2019 Sep 30 doi: 10.1016/j.abd.2019.09.023. PMID: 31777350Free PMC Article

Recent clinical studies

Etiology

Genetic diseases associated with an increased risk of skin cancer development in childhood.
Fogel AL, Sarin KY, Teng JMC
Curr Opin Pediatr 2017 Aug;29(4):426-433. doi: 10.1097/MOP.0000000000000514. PMID: 28525403
XPD Lys751Gln and Asp312Asn polymorphisms and susceptibility to skin cancer: a meta-analysis of 17 case-control studies.
Zhu HL, Bao JM, Lin PX, Li WX, Zou ZN, Huang YE, Chen Q, Shen H
Asian Pac J Cancer Prev 2014;15(16):6619-25. doi: 10.7314/apjcp.2014.15.16.6619. PMID: 25169498
MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.
García-Borrón JC, Abdel-Malek Z, Jiménez-Cervantes C
Pigment Cell Melanoma Res 2014 Sep;27(5):699-720. Epub 2014 May 30 doi: 10.1111/pcmr.12257. PMID: 24807163Free PMC Article
Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility.
Healy E
Photodermatol Photoimmunol Photomed 2004 Dec;20(6):283-8. doi: 10.1111/j.1600-0781.2004.00132.x. PMID: 15533235
Trichothiodystrophy, a transcription syndrome.
Bergmann E, Egly JM
Trends Genet 2001 May;17(5):279-86. doi: 10.1016/s0168-9525(01)02280-6. PMID: 11335038

Diagnosis

Genetic variants associated with skin photosensitivity in a southern European population from Spain.
Hernando B, Sanz-Page E, Pitarch G, Mahiques L, Valcuende-Cavero F, Martinez-Cadenas C
Photodermatol Photoimmunol Photomed 2018 Nov;34(6):415-422. Epub 2018 Jul 25 doi: 10.1111/phpp.12412. PMID: 29974532
Genetic diseases associated with an increased risk of skin cancer development in childhood.
Fogel AL, Sarin KY, Teng JMC
Curr Opin Pediatr 2017 Aug;29(4):426-433. doi: 10.1097/MOP.0000000000000514. PMID: 28525403
Basal cell carcinoma and anthropometric factors in the U.S. radiologic technologists cohort study.
Gerstenblith MR, Rajaraman P, Khaykin E, Doody MM, Alexander BH, Linet MS, Freedman DM
Int J Cancer 2012 Jul 15;131(2):E149-55. Epub 2012 Jan 31 doi: 10.1002/ijc.26480. PMID: 21989791Free PMC Article
Genetic predisposition to skin cancer.
Halpern AC, Altman JF
Curr Opin Oncol 1999 Mar;11(2):132-8. doi: 10.1097/00001622-199903000-00010. PMID: 10188079
Impaired interferon production and natural killer cell activation in patients with the skin cancer-prone disorder, xeroderma pigmentosum.
Gaspari AA, Fleisher TA, Kraemer KH
J Clin Invest 1993 Sep;92(3):1135-42. doi: 10.1172/JCI116682. PMID: 7690772Free PMC Article

Therapy

Genetic diseases associated with an increased risk of skin cancer development in childhood.
Fogel AL, Sarin KY, Teng JMC
Curr Opin Pediatr 2017 Aug;29(4):426-433. doi: 10.1097/MOP.0000000000000514. PMID: 28525403
Androgen receptor actions modify skin structure and chemical carcinogen-induced skin cancer susceptibility in mice.
Simanainen U, Ryan T, Li D, Suarez FG, Gao YR, Watson G, Wang Y, Handelsman DJ
Horm Cancer 2015 Feb;6(1):45-53. Epub 2015 Jan 7 doi: 10.1007/s12672-014-0210-1. PMID: 25563841Free PMC Article
MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.
García-Borrón JC, Abdel-Malek Z, Jiménez-Cervantes C
Pigment Cell Melanoma Res 2014 Sep;27(5):699-720. Epub 2014 May 30 doi: 10.1111/pcmr.12257. PMID: 24807163Free PMC Article
Melanocortin 1 receptor variants: functional role and pigmentary associations.
Dessinioti C, Antoniou C, Katsambas A, Stratigos AJ
Photochem Photobiol 2011 Sep-Oct;87(5):978-87. Epub 2011 Aug 17 doi: 10.1111/j.1751-1097.2011.00970.x. PMID: 21749400
TP53 Arg72Pro polymorphism and skin cancer risk: a meta-analysis.
Jiang DK, Wang WZ, Ren WH, Yao L, Peng B, Yu L
J Invest Dermatol 2011 Jan;131(1):220-8. Epub 2010 Sep 23 doi: 10.1038/jid.2010.270. PMID: 20861852

Prognosis

Inflammatory Bowel Disease Risk Variants Are Associated with an Increased Risk of Skin Cancer.
Cushing KC, Du X, Chen Y, Stetson LC, Kuppa A, Chen VL, Kahlenberg JM, Gudjonsson JE, Vanderwerff B, Higgins PDR, Speliotes EK
Inflamm Bowel Dis 2022 Nov 2;28(11):1667-1676. doi: 10.1093/ibd/izab336. PMID: 35018451Free PMC Article
Diffuse Reflectance Spectroscopy as a Reliable Means of Comparing Ultraviolet Radiation-induced Erythema in Extreme Skin Colors.
Fajuyigbe D, Coleman A, Sarkany RPE, Young AR, Schmalwieser AW
Photochem Photobiol 2018 Sep;94(5):1066-1070. Epub 2018 Jul 4 doi: 10.1111/php.12947. PMID: 29869793
Polymorphisms in the vitamin D receptor (VDR) genes and skin cancer risk in European population: a meta-analysis.
Zhao XZ, Yang BH, Yu GH, Liu SZ, Yuan ZY
Arch Dermatol Res 2014 Aug;306(6):545-53. Epub 2014 Apr 28 doi: 10.1007/s00403-014-1464-8. PMID: 24771013
Current status of pharmacogenomics testing for anti-tumor drug therapies: approaches to non-melanoma skin cancer.
Grealy R, Griffiths LR
Mol Diagn Ther 2009;13(2):65-72. doi: 10.1007/BF03256316. PMID: 19537842

Clinical prediction guides

Meta-analysis of the Correlation Between Interleukin-6 Promoter Polymorphism -174G/C and Interferon Regulatory Factor 4 rs12203592 Polymorphism With Skin Cancer Susceptibility.
Wu M, Cao Y, Liu YL, Ma LL, Yang XH
Am J Ther 2016 Nov/Dec;23(6):e1758-e1767. doi: 10.1097/MJT.0000000000000429. PMID: 26928068
Androgen receptor actions modify skin structure and chemical carcinogen-induced skin cancer susceptibility in mice.
Simanainen U, Ryan T, Li D, Suarez FG, Gao YR, Watson G, Wang Y, Handelsman DJ
Horm Cancer 2015 Feb;6(1):45-53. Epub 2015 Jan 7 doi: 10.1007/s12672-014-0210-1. PMID: 25563841Free PMC Article
XPD Lys751Gln and Asp312Asn polymorphisms and susceptibility to skin cancer: a meta-analysis of 17 case-control studies.
Zhu HL, Bao JM, Lin PX, Li WX, Zou ZN, Huang YE, Chen Q, Shen H
Asian Pac J Cancer Prev 2014;15(16):6619-25. doi: 10.7314/apjcp.2014.15.16.6619. PMID: 25169498
Arg72Pro polymorphism of TP53 gene and the risk of skin cancer: a meta-analysis.
Ye J, Li XF, Wang YD, Yuan Y
PLoS One 2013;8(11):e79983. Epub 2013 Nov 8 doi: 10.1371/journal.pone.0079983. PMID: 24260330Free PMC Article
TP53 Arg72Pro polymorphism and skin cancer risk: a meta-analysis.
Jiang DK, Wang WZ, Ren WH, Yao L, Peng B, Yu L
J Invest Dermatol 2011 Jan;131(1):220-8. Epub 2010 Sep 23 doi: 10.1038/jid.2010.270. PMID: 20861852

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