U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Parainfluenza Virus Infection

MedGen UID:
81296
•Concept ID:
C0302507
•
Disease or Syndrome
Synonyms: Infection, Parainfluenza Virus; Infections, Parainfluenza Virus; Parainfluenza Virus Infections; Virus Infection, Parainfluenza; Virus Infections, Parainfluenza

Definition

A viral infection caused by a parainfluenza virus, typically resulting in infections of the lower respiratory tract. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParainfluenza Virus Infection

Professional guidelines

PubMed

Human parainfluenza virus infection after hematopoietic stem cell transplantation: risk factors, management, mortality, and changes over time.
Ustun C, Slabý J, Shanley RM, Vydra J, Smith AR, Wagner JE, Weisdorf DJ, Young JA
Biol Blood Marrow Transplant 2012 Oct;18(10):1580-8. Epub 2012 Apr 21 doi: 10.1016/j.bbmt.2012.04.012. PMID: 22531491Free PMC Article

Recent clinical studies

Etiology

Seasonal epidemiological and clinical characteristics of pediatric patients with human parainfluenza virus infection by serotype: a retrospective study.
Han JY, Suh W, Han SB
Virol J 2022 Sep 6;19(1):141. doi: 10.1186/s12985-022-01875-2. PMID: 36064562Free PMC Article
Parainfluenza Virus Infection in an Australian Community-based Birth Cohort.
Saha S, Grimwood K, Lambert SB, Sarna M, Ware RS
Pediatr Infect Dis J 2020 Sep;39(9):e284-e287. doi: 10.1097/INF.0000000000002796. PMID: 32804465
Human parainfluenza virus infection in severe acute respiratory infection cases in Beijing, 2014-2016: A molecular epidemiological study.
Pan Y, Zhang Y, Shi W, Peng X, Cui S, Zhang D, Lu G, Liu Y, Wu S, Yang P, Wang Q
Influenza Other Respir Viruses 2017 Nov;11(6):564-568. doi: 10.1111/irv.12514. PMID: 29054112Free PMC Article
Human parainfluenza virus infection after hematopoietic stem cell transplantation: risk factors, management, mortality, and changes over time.
Ustun C, Slabý J, Shanley RM, Vydra J, Smith AR, Wagner JE, Weisdorf DJ, Young JA
Biol Blood Marrow Transplant 2012 Oct;18(10):1580-8. Epub 2012 Apr 21 doi: 10.1016/j.bbmt.2012.04.012. PMID: 22531491Free PMC Article
Parainfluenza virus infection in adult lung transplant recipients: an emergent clinical syndrome with implications on allograft function.
Vilchez RA, Dauber J, McCurry K, Iacono A, Kusne S
Am J Transplant 2003 Feb;3(2):116-20. doi: 10.1034/j.1600-6143.2003.00024.x. PMID: 12603206

Diagnosis

Seasonal epidemiological and clinical characteristics of pediatric patients with human parainfluenza virus infection by serotype: a retrospective study.
Han JY, Suh W, Han SB
Virol J 2022 Sep 6;19(1):141. doi: 10.1186/s12985-022-01875-2. PMID: 36064562Free PMC Article
Parainfluenza Virus Infection Sensitizes Cancer Cells to DNA-Damaging Agents: Implications for Oncolytic Virus Therapy.
Fox CR, Parks GD
J Virol 2018 Apr 1;92(7) Epub 2018 Mar 14 doi: 10.1128/JVI.01948-17. PMID: 29343567Free PMC Article
Parainfluenza Virus Infection.
Branche AR, Falsey AR
Semin Respir Crit Care Med 2016 Aug;37(4):538-54. Epub 2016 Aug 3 doi: 10.1055/s-0036-1584798. PMID: 27486735Free PMC Article
Impact of parainfluenza virus infection in pediatric cancer patients.
Maeng SH, Yoo HS, Choi SH, Yoo KH, Kim YJ, Sung KW, Lee NY, Koo HH
Pediatr Blood Cancer 2012 Oct;59(4):708-10. Epub 2011 Nov 2 doi: 10.1002/pbc.23390. PMID: 22095941
Parainfluenza virus infection in adult lung transplant recipients: an emergent clinical syndrome with implications on allograft function.
Vilchez RA, Dauber J, McCurry K, Iacono A, Kusne S
Am J Transplant 2003 Feb;3(2):116-20. doi: 10.1034/j.1600-6143.2003.00024.x. PMID: 12603206

Therapy

Epicatechin analogues may hinder human parainfluenza virus infection by inhibition of hemagglutinin neuraminidase protein and prevention of cellular entry.
Bhasin S, Nadar M, Hasija Y
J Mol Model 2022 Sep 16;28(10):319. doi: 10.1007/s00894-022-05310-9. PMID: 36109366
Human parainfluenza virus infection after hematopoietic stem cell transplantation: risk factors, management, mortality, and changes over time.
Ustun C, Slabý J, Shanley RM, Vydra J, Smith AR, Wagner JE, Weisdorf DJ, Young JA
Biol Blood Marrow Transplant 2012 Oct;18(10):1580-8. Epub 2012 Apr 21 doi: 10.1016/j.bbmt.2012.04.012. PMID: 22531491Free PMC Article
Parainfluenza virus infection in adult lung transplant recipients: an emergent clinical syndrome with implications on allograft function.
Vilchez RA, Dauber J, McCurry K, Iacono A, Kusne S
Am J Transplant 2003 Feb;3(2):116-20. doi: 10.1034/j.1600-6143.2003.00024.x. PMID: 12603206
Parainfluenza virus infection among adults hospitalized for lower respiratory tract infection.
Marx A, Gary HE Jr, Marston BJ, Erdman DD, Breiman RF, Török TJ, Plouffe JF, File TM Jr, Anderson LJ
Clin Infect Dis 1999 Jul;29(1):134-40. doi: 10.1086/520142. PMID: 10433576
Ribavirin: a clinical overview.
Fernandez H, Banks G, Smith R
Eur J Epidemiol 1986 Mar;2(1):1-14. doi: 10.1007/BF00152711. PMID: 3021519

Prognosis

Epicatechin analogues may hinder human parainfluenza virus infection by inhibition of hemagglutinin neuraminidase protein and prevention of cellular entry.
Bhasin S, Nadar M, Hasija Y
J Mol Model 2022 Sep 16;28(10):319. doi: 10.1007/s00894-022-05310-9. PMID: 36109366
Parainfluenza Virus Infection in an Australian Community-based Birth Cohort.
Saha S, Grimwood K, Lambert SB, Sarna M, Ware RS
Pediatr Infect Dis J 2020 Sep;39(9):e284-e287. doi: 10.1097/INF.0000000000002796. PMID: 32804465
Immunodeficiency risk score for prediction of mortality by parainfluenza virus infection in patients with hematologic malignancy.
Lee J, Jung J, Kim MJ, Chong YP, Lee SO, Choi SH, Kim YS, Woo JH, Choi EJ, Park HS, Lee JH, Lee JH, Lee KH, Kim SH
Ann Hematol 2020 Jun;99(6):1231-1239. Epub 2020 May 7 doi: 10.1007/s00277-020-03996-6. PMID: 32382770Free PMC Article
Human parainfluenza virus infection after hematopoietic stem cell transplantation: risk factors, management, mortality, and changes over time.
Ustun C, Slabý J, Shanley RM, Vydra J, Smith AR, Wagner JE, Weisdorf DJ, Young JA
Biol Blood Marrow Transplant 2012 Oct;18(10):1580-8. Epub 2012 Apr 21 doi: 10.1016/j.bbmt.2012.04.012. PMID: 22531491Free PMC Article
Parainfluenza virus infection in adult lung transplant recipients: an emergent clinical syndrome with implications on allograft function.
Vilchez RA, Dauber J, McCurry K, Iacono A, Kusne S
Am J Transplant 2003 Feb;3(2):116-20. doi: 10.1034/j.1600-6143.2003.00024.x. PMID: 12603206

Clinical prediction guides

Epicatechin analogues may hinder human parainfluenza virus infection by inhibition of hemagglutinin neuraminidase protein and prevention of cellular entry.
Bhasin S, Nadar M, Hasija Y
J Mol Model 2022 Sep 16;28(10):319. doi: 10.1007/s00894-022-05310-9. PMID: 36109366
Seasonal epidemiological and clinical characteristics of pediatric patients with human parainfluenza virus infection by serotype: a retrospective study.
Han JY, Suh W, Han SB
Virol J 2022 Sep 6;19(1):141. doi: 10.1186/s12985-022-01875-2. PMID: 36064562Free PMC Article
An Online Observational Study of Patients With Olfactory and Gustory Alterations Secondary to SARS-CoV-2 Infection.
Gómez-Iglesias P, Porta-Etessam J, Montalvo T, Valls-Carbó A, Gajate V, Matías-Guiu JA, Parejo-Carbonell B, González-García N, Ezpeleta D, Láinez JM, Matías-Guiu J
Front Public Health 2020;8:243. Epub 2020 May 29 doi: 10.3389/fpubh.2020.00243. PMID: 32574308Free PMC Article
Immunodeficiency risk score for prediction of mortality by parainfluenza virus infection in patients with hematologic malignancy.
Lee J, Jung J, Kim MJ, Chong YP, Lee SO, Choi SH, Kim YS, Woo JH, Choi EJ, Park HS, Lee JH, Lee JH, Lee KH, Kim SH
Ann Hematol 2020 Jun;99(6):1231-1239. Epub 2020 May 7 doi: 10.1007/s00277-020-03996-6. PMID: 32382770Free PMC Article
Role of parainfluenza virus-specific IgE in pathogenesis of croup and wheezing subsequent to infection.
Welliver RC, Wong DT, Middleton E Jr, Sun M, McCarthy N, Ogra PL
J Pediatr 1982 Dec;101(6):889-96. doi: 10.1016/s0022-3476(82)80005-x. PMID: 6183418

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...