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Thinned hair follicle epithelium

MedGen UID:
813438
•Concept ID:
C3807108
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThinned hair follicle epithelium

Professional guidelines

PubMed

Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways.
Wang Q, Zhou M, Zhang H, Hou Z, Liu D
Int J Mol Sci 2023 Jul 7;24(13) doi: 10.3390/ijms241311198. PMID: 37446376Free PMC Article
Minimally invasive procedures for the management of female pattern hair loss.
Melo DF, Cortez de Almeida RF, Frattini SC, Santos LDN, Ramos PM
J Cosmet Dermatol 2022 Nov;21(11):5405-5408. Epub 2022 Jun 25 doi: 10.1111/jocd.15160. PMID: 35713007
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
Nestor MS, Ablon G, Gade A, Han H, Fischer DL
J Cosmet Dermatol 2021 Dec;20(12):3759-3781. Epub 2021 Nov 6 doi: 10.1111/jocd.14537. PMID: 34741573Free PMC Article

Recent clinical studies

Etiology

The Transfer of Expanded Forehead Superthin Flap Without Frontalis and Less Hair Follicles Pedicled by Superficial Temporal Vessels.
Cao Z, Liu L, Jiao H, Fan J, Gan C, Zhang T
Ann Plast Surg 2023 Feb 1;90(2):128-132. doi: 10.1097/SAP.0000000000003416. PMID: 36688855
MR Imaging of Hair and Scalp for the Evaluation of Androgenetic Alopecia.
Soga S, Koyama T, Mikoshi A, Arafune T, Kawashima M, Kobayashi K, Shinmoto H
Magn Reson Med Sci 2021 Jun 1;20(2):160-165. Epub 2020 May 1 doi: 10.2463/mrms.mp.2020-0026. PMID: 32378681Free PMC Article
Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients.
Starace M, Orlando G, Alessandrini A, Baraldi C, Bruni F, Piraccini BM
J Am Acad Dermatol 2020 Dec;83(6):1659-1667. Epub 2019 Nov 9 doi: 10.1016/j.jaad.2019.11.006. PMID: 31706933
Non-scarring patchy alopecia in patients with systemic lupus erythematosus differs from that of alopecia areata.
Ye Y, Zhao Y, Gong Y, Zhang X, Caulloo S, Zhang B, Cai Z, Yang J, McElwee KJ, Zhang X
Lupus 2013 Dec;22(14):1439-45. Epub 2013 Oct 16 doi: 10.1177/0961203313508833. PMID: 24132518
Occipital involvement in female pattern hair loss: histopathological evidences.
Ekmekci TR, Sakiz D, Koslu A
J Eur Acad Dermatol Venereol 2010 Mar;24(3):299-301. Epub 2009 Aug 23 doi: 10.1111/j.1468-3083.2009.03411.x. PMID: 19703099

Diagnosis

An updated review of the sebaceous gland and its role in health and diseases Part 2: Pathophysiological clinical disorders of sebaceous glands.
Shamloul G, Khachemoune A
Dermatol Ther 2021 Mar;34(2):e14862. Epub 2021 Feb 19 doi: 10.1111/dth.14862. PMID: 33571388
The diagnosis of androgenetic alopecia in children: Considerations of pathophysiological plausibility.
Rossi A, D'Arino A, Pigliacelli F, Caro G, Muscianese M, Fortuna MC, Carlesimo M
Australas J Dermatol 2019 Nov;60(4):e279-e283. Epub 2019 Jun 6 doi: 10.1111/ajd.13079. PMID: 31168786
Hair disorders associated with autoimmune connective tissue diseases.
Cassano N, Amerio P, D'Ovidio R, Vena GA
G Ital Dermatol Venereol 2014 Oct;149(5):555-65. Epub 2014 Jun 30 PMID: 24975949
Androgenetic alopecia.
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Molecular mechanisms of androgenetic alopecia.
Trüeb RM
Exp Gerontol 2002 Aug-Sep;37(8-9):981-90. doi: 10.1016/s0531-5565(02)00093-1. PMID: 12213548

Therapy

Minimally invasive procedures for the management of female pattern hair loss.
Melo DF, Cortez de Almeida RF, Frattini SC, Santos LDN, Ramos PM
J Cosmet Dermatol 2022 Nov;21(11):5405-5408. Epub 2022 Jun 25 doi: 10.1111/jocd.15160. PMID: 35713007
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
Nestor MS, Ablon G, Gade A, Han H, Fischer DL
J Cosmet Dermatol 2021 Dec;20(12):3759-3781. Epub 2021 Nov 6 doi: 10.1111/jocd.14537. PMID: 34741573Free PMC Article
Normal and aging hair biology and structure 'aging and hair'.
Goodier M, Hordinsky M
Curr Probl Dermatol 2015;47:1-9. Epub 2015 Feb 20 doi: 10.1159/000369594. PMID: 26370639
Hair disorders associated with autoimmune connective tissue diseases.
Cassano N, Amerio P, D'Ovidio R, Vena GA
G Ital Dermatol Venereol 2014 Oct;149(5):555-65. Epub 2014 Jun 30 PMID: 24975949
Androgenetic alopecia.
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563

Prognosis

Hormones and clocks: do they disrupt the locks? Fluctuating estrogen levels during menopausal transition may influence clock genes and trigger chronic telogen effluvium.
Mirmirani P
Dermatol Online J 2016 May 15;22(5) PMID: 27617515
Normal and aging hair biology and structure 'aging and hair'.
Goodier M, Hordinsky M
Curr Probl Dermatol 2015;47:1-9. Epub 2015 Feb 20 doi: 10.1159/000369594. PMID: 26370639
Hair disorders associated with autoimmune connective tissue diseases.
Cassano N, Amerio P, D'Ovidio R, Vena GA
G Ital Dermatol Venereol 2014 Oct;149(5):555-65. Epub 2014 Jun 30 PMID: 24975949
Androgenetic alopecia.
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Occipital involvement in female pattern hair loss: histopathological evidences.
Ekmekci TR, Sakiz D, Koslu A
J Eur Acad Dermatol Venereol 2010 Mar;24(3):299-301. Epub 2009 Aug 23 doi: 10.1111/j.1468-3083.2009.03411.x. PMID: 19703099

Clinical prediction guides

β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress.
Xu C, Dai J, Ai H, Du W, Ji H
Molecules 2024 Feb 8;29(4) doi: 10.3390/molecules29040798. PMID: 38398550Free PMC Article
MR Imaging of Hair and Scalp for the Evaluation of Androgenetic Alopecia.
Soga S, Koyama T, Mikoshi A, Arafune T, Kawashima M, Kobayashi K, Shinmoto H
Magn Reson Med Sci 2021 Jun 1;20(2):160-165. Epub 2020 May 1 doi: 10.2463/mrms.mp.2020-0026. PMID: 32378681Free PMC Article
Getting under the skin of hair aging: the impact of the hair follicle environment.
Williams R, Pawlus AD, Thornton MJ
Exp Dermatol 2020 Jul;29(7):588-597. doi: 10.1111/exd.14109. PMID: 32358903
Hair disorders associated with autoimmune connective tissue diseases.
Cassano N, Amerio P, D'Ovidio R, Vena GA
G Ital Dermatol Venereol 2014 Oct;149(5):555-65. Epub 2014 Jun 30 PMID: 24975949
Hair loss in pityriasis versicolor lesions: a descriptive clinicopathological study.
Mostafa WZ, Assaf MI, Ameen IA, El Safoury OS, Al Sulh SA
J Am Acad Dermatol 2013 Jul;69(1):e19-23. Epub 2012 May 8 doi: 10.1016/j.jaad.2012.03.004. PMID: 22575159

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