U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Advanced sleep phase syndrome 2(FASPS2)

MedGen UID:
815204
Concept ID:
C3808874
Disease or Syndrome
Synonym: Advanced sleep phase syndrome, familial, 2
 
Gene (location): CSNK1D (17q25.3)
 
Monarch Initiative: MONDO:0014088
OMIM®: 615224

Definition

Advanced sleep phase syndrome is characterized by very early sleep onset and offset (summary by Jones et al., 1999). For a discussion of genetic heterogeneity of advanced sleep phase syndrome, see FASPS1 (604348). [from OMIM]

Clinical features

From HPO
Migraine
MedGen UID:
57451
Concept ID:
C0149931
Disease or Syndrome
Migraine is a chronic neurological disorder characterized by episodic attacks of headache and associated symptoms.
Migraine with aura
MedGen UID:
57822
Concept ID:
C0154723
Disease or Syndrome
A type of migraine in which there is an aura characterized by focal neurological phenomena that usually proceed, but may accompany or occur in the absence of, the headache. The symptoms of an aura may include fully reversible visual, sensory, and speech symptoms but not motor weakness. Visual symptoms may include flickering lights, spots and lines and/or loss of vision and/or unilateral sensory symptoms such as paresthesias or numbness. At least one of the symptoms of an aura develops gradually over 5 or more minutes and/or different symptoms occur in succession.
Migraine without aura
MedGen UID:
137899
Concept ID:
C0338480
Disease or Syndrome
Repeated headache attacks lasting 4-72 h fulfilling at least two of the following criteria
Sleep-wake cycle disturbance
MedGen UID:
371548
Concept ID:
C1833362
Finding
Any abnormality of an individual's circadian rhythm that affects the timing of sleeping and being awake is referred to as a sleep-wake disorder.
Early chronotype
MedGen UID:
1646349
Concept ID:
C4703587
Finding
A tendency towards rising very early in the morning and going to bed early in the evening.

Professional guidelines

PubMed

de Bergeyck R, Geoffroy PA
Rev Neurol (Paris) 2023 Oct;179(7):767-781. Epub 2023 Aug 22 doi: 10.1016/j.neurol.2023.08.008. PMID: 37620177
Wilson S, Anderson K, Baldwin D, Dijk DJ, Espie A, Espie C, Gringras P, Krystal A, Nutt D, Selsick H, Sharpley A
J Psychopharmacol 2019 Aug;33(8):923-947. Epub 2019 Jul 4 doi: 10.1177/0269881119855343. PMID: 31271339
Herxheimer A, Petrie KJ
Cochrane Database Syst Rev 2002;(2):CD001520. doi: 10.1002/14651858.CD001520. PMID: 12076414

Recent clinical studies

Etiology

Di H, Guo Y, Daghlas I, Wang L, Liu G, Pan A, Liu L, Shan Z
JAMA Netw Open 2022 Nov 1;5(11):e2240788. doi: 10.1001/jamanetworkopen.2022.40788. PMID: 36346632Free PMC Article
Schipper SBJ, Van Veen MM, Elders PJM, van Straten A, Van Der Werf YD, Knutson KL, Rutters F
Diabetologia 2021 Nov;64(11):2367-2377. Epub 2021 Aug 16 doi: 10.1007/s00125-021-05541-0. PMID: 34401953Free PMC Article
Ikegami K, Refetoff S, Van Cauter E, Yoshimura T
Nat Rev Endocrinol 2019 Oct;15(10):590-600. Epub 2019 Aug 12 doi: 10.1038/s41574-019-0237-z. PMID: 31406343Free PMC Article
Zimmet P, Alberti KGMM, Stern N, Bilu C, El-Osta A, Einat H, Kronfeld-Schor N
J Intern Med 2019 Aug;286(2):181-191. Epub 2019 Jun 10 doi: 10.1111/joim.12924. PMID: 31081577Free PMC Article
Boivin DB, Boudreau P
Pathol Biol (Paris) 2014 Oct;62(5):292-301. Epub 2014 Sep 20 doi: 10.1016/j.patbio.2014.08.001. PMID: 25246026

Diagnosis

Kim JH, Elkhadem AR, Duffy JF
Sleep Med Clin 2022 Jun;17(2):241-252. doi: 10.1016/j.jsmc.2022.02.003. PMID: 35659077Free PMC Article
Cardinali DP, Brown GM, Pandi-Perumal SR
Handb Clin Neurol 2021;179:357-370. doi: 10.1016/B978-0-12-819975-6.00023-6. PMID: 34225975
Sateia MJ
Chest 2014 Nov;146(5):1387-1394. doi: 10.1378/chest.14-0970. PMID: 25367475
Depner CM, Stothard ER, Wright KP Jr
Curr Diab Rep 2014 Jul;14(7):507. doi: 10.1007/s11892-014-0507-z. PMID: 24816752Free PMC Article
Lund HG, Reider BD, Whiting AB, Prichard JR
J Adolesc Health 2010 Feb;46(2):124-32. Epub 2009 Aug 3 doi: 10.1016/j.jadohealth.2009.06.016. PMID: 20113918

Therapy

Duffy JF, Wang W, Ronda JM, Czeisler CA
J Pineal Res 2022 Aug;73(1):e12801. Epub 2022 May 13 doi: 10.1111/jpi.12801. PMID: 35436355Free PMC Article
Schipper SBJ, Van Veen MM, Elders PJM, van Straten A, Van Der Werf YD, Knutson KL, Rutters F
Diabetologia 2021 Nov;64(11):2367-2377. Epub 2021 Aug 16 doi: 10.1007/s00125-021-05541-0. PMID: 34401953Free PMC Article
Ganesan S, Magee M, Stone JE, Mulhall MD, Collins A, Howard ME, Lockley SW, Rajaratnam SMW, Sletten TL
Sci Rep 2019 Mar 15;9(1):4635. doi: 10.1038/s41598-019-40914-x. PMID: 30874565Free PMC Article
Boivin DB, Boudreau P
Pathol Biol (Paris) 2014 Oct;62(5):292-301. Epub 2014 Sep 20 doi: 10.1016/j.patbio.2014.08.001. PMID: 25246026
Huang W, Ramsey KM, Marcheva B, Bass J
J Clin Invest 2011 Jun;121(6):2133-41. Epub 2011 Jun 1 doi: 10.1172/JCI46043. PMID: 21633182Free PMC Article

Prognosis

Richmond RC, Anderson EL, Dashti HS, Jones SE, Lane JM, Strand LB, Brumpton B, Rutter MK, Wood AR, Straif K, Relton CL, Munafò M, Frayling TM, Martin RM, Saxena R, Weedon MN, Lawlor DA, Smith GD
BMJ 2019 Jun 26;365:l2327. doi: 10.1136/bmj.l2327. PMID: 31243001Free PMC Article
Bathory E, Tomopoulos S
Curr Probl Pediatr Adolesc Health Care 2017 Feb;47(2):29-42. Epub 2017 Jan 20 doi: 10.1016/j.cppeds.2016.12.001. PMID: 28117135
Papagiannakopoulos T, Bauer MR, Davidson SM, Heimann M, Subbaraj L, Bhutkar A, Bartlebaugh J, Vander Heiden MG, Jacks T
Cell Metab 2016 Aug 9;24(2):324-31. Epub 2016 Jul 28 doi: 10.1016/j.cmet.2016.07.001. PMID: 27476975Free PMC Article
Boivin DB, Boudreau P
Pathol Biol (Paris) 2014 Oct;62(5):292-301. Epub 2014 Sep 20 doi: 10.1016/j.patbio.2014.08.001. PMID: 25246026
Lund HG, Reider BD, Whiting AB, Prichard JR
J Adolesc Health 2010 Feb;46(2):124-32. Epub 2009 Aug 3 doi: 10.1016/j.jadohealth.2009.06.016. PMID: 20113918

Clinical prediction guides

Schipper SBJ, Van Veen MM, Elders PJM, van Straten A, Van Der Werf YD, Knutson KL, Rutters F
Diabetologia 2021 Nov;64(11):2367-2377. Epub 2021 Aug 16 doi: 10.1007/s00125-021-05541-0. PMID: 34401953Free PMC Article
Phillips AJK, Clerx WM, O'Brien CS, Sano A, Barger LK, Picard RW, Lockley SW, Klerman EB, Czeisler CA
Sci Rep 2017 Jun 12;7(1):3216. doi: 10.1038/s41598-017-03171-4. PMID: 28607474Free PMC Article
Boivin DB, Boudreau P
Pathol Biol (Paris) 2014 Oct;62(5):292-301. Epub 2014 Sep 20 doi: 10.1016/j.patbio.2014.08.001. PMID: 25246026
Huang W, Ramsey KM, Marcheva B, Bass J
J Clin Invest 2011 Jun;121(6):2133-41. Epub 2011 Jun 1 doi: 10.1172/JCI46043. PMID: 21633182Free PMC Article
Lund HG, Reider BD, Whiting AB, Prichard JR
J Adolesc Health 2010 Feb;46(2):124-32. Epub 2009 Aug 3 doi: 10.1016/j.jadohealth.2009.06.016. PMID: 20113918

Recent systematic reviews

Arab A, Karimi E, Garaulet M, Scheer FAJL
Obes Rev 2024 Mar;25(3):e13664. Epub 2023 Dec 10 doi: 10.1111/obr.13664. PMID: 38072635
Cheung FTW, Li X, Hui TK, Chan NY, Chan JW, Wing YK, Li SX
Sleep Med Rev 2023 Dec;72:101851. Epub 2023 Sep 17 doi: 10.1016/j.smrv.2023.101851. PMID: 37793219
Torquati L, Mielke GI, Brown WJ, Burton NW, Kolbe-Alexander TL
Am J Public Health 2019 Nov;109(11):e13-e20. Epub 2019 Sep 19 doi: 10.2105/AJPH.2019.305278. PMID: 31536404Free PMC Article
Wilson S, Anderson K, Baldwin D, Dijk DJ, Espie A, Espie C, Gringras P, Krystal A, Nutt D, Selsick H, Sharpley A
J Psychopharmacol 2019 Aug;33(8):923-947. Epub 2019 Jul 4 doi: 10.1177/0269881119855343. PMID: 31271339
Herxheimer A, Petrie KJ
Cochrane Database Syst Rev 2002;(2):CD001520. doi: 10.1002/14651858.CD001520. PMID: 12076414

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...