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Aortitis

MedGen UID:
8154
•Concept ID:
C0003509
•
Disease or Syndrome
Synonym: Aortitides
SNOMED CT: Aortitis (70933002)
 
Monarch Initiative: MONDO:0006656

Definition

Inflammation of the aorta. Causes include trauma, infectious disorders, and connective tissue disorders. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAortitis

Professional guidelines

PubMed

2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.
Writing Committee Members, Isselbacher EM, Preventza O, Hamilton Black Iii J, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A Jr, Fanola CL, Girardi LN, Hicks CW, Hui DS, Jones WS, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Ross EG, Schermerhorn ML, Times SS, Tseng EE, Wang GJ, Woo YJ
J Am Coll Cardiol 2022 Dec 13;80(24):e223-e393. Epub 2022 Nov 2 doi: 10.1016/j.jacc.2022.08.004. PMID: 36334952Free PMC Article
2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.
Isselbacher EM, Preventza O, Hamilton Black J 3rd, Augoustides JG, Beck AW, Bolen MA, Braverman AC, Bray BE, Brown-Zimmerman MM, Chen EP, Collins TJ, DeAnda A Jr, Fanola CL, Girardi LN, Hicks CW, Hui DS, Schuyler Jones W, Kalahasti V, Kim KM, Milewicz DM, Oderich GS, Ogbechie L, Promes SB, Gyang Ross E, Schermerhorn ML, Singleton Times S, Tseng EE, Wang GJ, Woo YJ; Peer Review Committee Members
Circulation 2022 Dec 13;146(24):e334-e482. Epub 2022 Nov 2 doi: 10.1161/CIR.0000000000001106. PMID: 36322642Free PMC Article
2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).
Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, Allmen RS, Vrints CJ; ESC Committee for Practice Guidelines
Eur Heart J 2014 Nov 1;35(41):2873-926. Epub 2014 Aug 29 doi: 10.1093/eurheartj/ehu281. PMID: 25173340

Recent clinical studies

Etiology

Aortitis: recent advances, current concepts and future possibilities.
Pugh D, Grayson P, Basu N, Dhaun N
Heart 2021 Oct;107(20):1620-1629. Epub 2021 Feb 16 doi: 10.1136/heartjnl-2020-318085. PMID: 33593995
Medium- and Large-Vessel Vasculitis.
Saadoun D, Vautier M, Cacoub P
Circulation 2021 Jan 19;143(3):267-282. doi: 10.1161/CIRCULATIONAHA.120.046657. PMID: 33464968
2018 Update of the EULAR recommendations for the management of large vessel vasculitis.
Hellmich B, Agueda A, Monti S, Buttgereit F, de Boysson H, Brouwer E, Cassie R, Cid MC, Dasgupta B, Dejaco C, Hatemi G, Hollinger N, Mahr A, Mollan SP, Mukhtyar C, Ponte C, Salvarani C, Sivakumar R, Tian X, Tomasson G, Turesson C, Schmidt W, Villiger PM, Watts R, Young C, Luqmani RA
Ann Rheum Dis 2020 Jan;79(1):19-30. Epub 2019 Jul 3 doi: 10.1136/annrheumdis-2019-215672. PMID: 31270110
Updates of Recent Aortic Aneurysm Research.
Davis FM, Daugherty A, Lu HS
Arterioscler Thromb Vasc Biol 2019 Mar;39(3):e83-e90. doi: 10.1161/ATVBAHA.119.312000. PMID: 30811252Free PMC Article
2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).
Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, Allmen RS, Vrints CJ; ESC Committee for Practice Guidelines
Eur Heart J 2014 Nov 1;35(41):2873-926. Epub 2014 Aug 29 doi: 10.1093/eurheartj/ehu281. PMID: 25173340

Diagnosis

Isolated Aortitis: Workup and Management.
Kermani TA, Byram K
Rheum Dis Clin North Am 2023 Aug;49(3):523-543. Epub 2023 Apr 28 doi: 10.1016/j.rdc.2023.03.013. PMID: 37331731
Aortitis: recent advances, current concepts and future possibilities.
Pugh D, Grayson P, Basu N, Dhaun N
Heart 2021 Oct;107(20):1620-1629. Epub 2021 Feb 16 doi: 10.1136/heartjnl-2020-318085. PMID: 33593995
Aortitis: an update.
Erdogan M
Curr Opin Rheumatol 2021 Jan;33(1):34-40. doi: 10.1097/BOR.0000000000000762. PMID: 33186247
Aortitis and periaortitis: The puzzling spectrum of inflammatory aortic diseases.
Marvisi C, Accorsi Buttini E, Vaglio A
Presse Med 2020 Apr;49(1):104018. Epub 2020 Mar 28 doi: 10.1016/j.lpm.2020.104018. PMID: 32234379
Aortitis.
Bossone E, Pluchinotta FR, Andreas M, Blanc P, Citro R, Limongelli G, Della Corte A, Parikh A, Frigiola A, Lerakis S, Ehrlich M, Aboyans V
Vascul Pharmacol 2016 May;80:1-10. Epub 2015 Dec 22 doi: 10.1016/j.vph.2015.11.084. PMID: 26721213

Therapy

Aortitis: an update.
Erdogan M
Curr Opin Rheumatol 2021 Jan;33(1):34-40. doi: 10.1097/BOR.0000000000000762. PMID: 33186247
2018 Update of the EULAR recommendations for the management of large vessel vasculitis.
Hellmich B, Agueda A, Monti S, Buttgereit F, de Boysson H, Brouwer E, Cassie R, Cid MC, Dasgupta B, Dejaco C, Hatemi G, Hollinger N, Mahr A, Mollan SP, Mukhtyar C, Ponte C, Salvarani C, Sivakumar R, Tian X, Tomasson G, Turesson C, Schmidt W, Villiger PM, Watts R, Young C, Luqmani RA
Ann Rheum Dis 2020 Jan;79(1):19-30. Epub 2019 Jul 3 doi: 10.1136/annrheumdis-2019-215672. PMID: 31270110
Takayasu Arteritis: Recent Developments.
Zaldivar Villon MLF, de la Rocha JAL, Espinoza LR
Curr Rheumatol Rep 2019 Jul 18;21(9):45. doi: 10.1007/s11926-019-0848-3. PMID: 31321560
Updates of Recent Aortic Aneurysm Research.
Davis FM, Daugherty A, Lu HS
Arterioscler Thromb Vasc Biol 2019 Mar;39(3):e83-e90. doi: 10.1161/ATVBAHA.119.312000. PMID: 30811252Free PMC Article
Tuberculosis and the Heart.
Mutyaba AK, Ntsekhe M
Cardiol Clin 2017 Feb;35(1):135-144. doi: 10.1016/j.ccl.2016.08.007. PMID: 27886784

Prognosis

Long-Term Outcome and Prognosis of Noninfectious Thoracic Aortitis.
Espitia O, Bruneval P, Assaraf M, Pouchot J, Liozon E, de Boysson H, Gaudric J, Chiche L, Achouh P, Roussel JC, Miranda S, Mirault T, Boussouar S, Redheuil A, Serfaty JM, Bénichou A, Agard C, Guédon AF, Cacoub P, Paraf F, Fouret PJ, Toquet C, Biard L, Saadoun D; French Study Group for Large Vessel Vasculitides (GEFA)
J Am Coll Cardiol 2023 Sep 12;82(11):1053-1064. doi: 10.1016/j.jacc.2023.06.031. PMID: 37673506
Isolated Aortitis: Workup and Management.
Kermani TA, Byram K
Rheum Dis Clin North Am 2023 Aug;49(3):523-543. Epub 2023 Apr 28 doi: 10.1016/j.rdc.2023.03.013. PMID: 37331731
Aortitis: an update.
Erdogan M
Curr Opin Rheumatol 2021 Jan;33(1):34-40. doi: 10.1097/BOR.0000000000000762. PMID: 33186247
Aortopathy in pregnancy.
Smok DA
Semin Perinatol 2014 Aug;38(5):295-303. doi: 10.1053/j.semperi.2014.04.019. PMID: 25037520
IgG4-related cardiovascular disorders.
Tajima M, Nagai R, Hiroi Y
Int Heart J 2014;55(4):287-95. Epub 2014 Jun 5 doi: 10.1536/ihj.13-321. PMID: 24898599

Clinical prediction guides

Persistent aortic inflammation in patients with giant cell arteritis.
Kaymakci MS, Boire NA, Bois MC, Elfishawi MM, Langenfeld HE, Hanson AC, Crowson CS, Koster MJ, Sato Y, Weyand CM, Warrington KJ
Autoimmun Rev 2023 Sep;22(9):103411. Epub 2023 Aug 18 doi: 10.1016/j.autrev.2023.103411. PMID: 37597603Free PMC Article
Aortitis: an update.
Erdogan M
Curr Opin Rheumatol 2021 Jan;33(1):34-40. doi: 10.1097/BOR.0000000000000762. PMID: 33186247
Imaging aortic wall inflammation.
Syed MBJ, Fletcher AJ, Dweck MR, Forsythe R, Newby DE
Trends Cardiovasc Med 2019 Nov;29(8):440-448. Epub 2018 Dec 27 doi: 10.1016/j.tcm.2018.12.003. PMID: 30611605Free PMC Article
Aortitis Presenting as Fever of Unknown Origin.
Yuan SM, Lin H
Ann Thorac Cardiovasc Surg 2018 Dec 20;24(6):279-287. Epub 2018 Aug 29 doi: 10.5761/atcs.ra.18-00136. PMID: 30158332Free PMC Article
PET in vasculitis.
Blockmans D
Ann N Y Acad Sci 2011 Jun;1228:64-70. doi: 10.1111/j.1749-6632.2011.06021.x. PMID: 21718324

Recent systematic reviews

Presentation and clinical course of pediatric-onset versus adult-onset Takayasu arteritis-a systematic review and meta-analysis.
Misra DP, Rathore U, Kopp CR, Patro P, Agarwal V, Sharma A
Clin Rheumatol 2022 Dec;41(12):3601-3613. Epub 2022 Aug 5 doi: 10.1007/s10067-022-06318-5. PMID: 35927524
Immunoglobulin G4-related coronary periarteritis: a systematic literature review with a case series.
Ito T, Fukui S, Kanie T, Tamaki H, Okada M
Clin Rheumatol 2022 Aug;41(8):2281-2295. Epub 2022 Apr 20 doi: 10.1007/s10067-022-06179-y. PMID: 35445950
Systematic literature review and meta-analysis of Clostridium septicum aortitis.
Kirchweger P, Wundsam H, Bosse F, Fritz A, Kratzer T, Kalteis M, Kupferthaler A, Böhm G, Kern D, Forstner M, Huemer R, Biebl M, Függer R
J Vasc Surg 2022 Aug;76(2):595-604.e1. Epub 2022 Mar 28 doi: 10.1016/j.jvs.2022.02.029. PMID: 35358668
Tuberculosis and the Heart.
López-López JP, Posada-Martínez EL, Saldarriaga C, Wyss F, Ponte-Negretti CI, Alexander B, Miranda-Arboleda AF, Martínez-Sellés M, Baranchuk A; Neglected Tropical Diseases, Other Infectious Diseases Affecting the Heart (the NET‐Heart Project)
J Am Heart Assoc 2021 Apr 6;10(7):e019435. Epub 2021 Mar 18 doi: 10.1161/JAHA.120.019435. PMID: 33733808Free PMC Article
Meta-analysis and meta-regression analysis of biomarkers for abdominal aortic aneurysm.
Stather PW, Sidloff DA, Dattani N, Gokani VJ, Choke E, Sayers RD, Bown MJ
Br J Surg 2014 Oct;101(11):1358-72. Epub 2014 Aug 18 doi: 10.1002/bjs.9593. PMID: 25131707

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