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Non-Rh Blood Group Isoimmunization

MedGen UID:
821551
•Concept ID:
C3828803
•
Finding
Synonym: Blood Group Isoimmunization

Definition

The mother develops antibodies against red blood cell non-Rhesus antigens. This may lead to potential fetal adverse outcomes such as anemia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Rh Blood Group Isoimmunization

Recent clinical studies

Etiology

Relationship between maternal antibody type and antenatal course following intrauterine transfusion for red cell alloimmunisation.
Walsh CA, Russell N, McAuliffe FM, Higgins S, Mahony R, Carroll S, McParland P
Eur J Obstet Gynecol Reprod Biol 2013 Dec;171(2):235-9. Epub 2013 Sep 8 doi: 10.1016/j.ejogrb.2013.09.002. PMID: 24075591
The clinical outcome of non-RhD antibody affected pregnancies in Northern Ireland.
Chandrasekar A, Morris KG, Tubman TR, Tharma S, McClelland WM
Ulster Med J 2001 Nov;70(2):89-94. PMID: 11795772Free PMC Article
Management of pregnancies complicated by rhesus (D) antibodies.
Welch CR, Makepeace PA, Walkinshaw SA
Br J Hosp Med 1993 Jun 2-15;49(11):813-6. PMID: 8334486
Percutaneous umbilical blood sampling: results from a multicenter collaborative registry. The Western Collaborative Perinatal Group.
Hickok DE, Mills M
Am J Obstet Gynecol 1992 Jun;166(6 Pt 1):1614-7; discussion 1617-8. doi: 10.1016/0002-9378(92)91550-t. PMID: 1615968

Diagnosis

Percutaneous umbilical blood sampling: results from a multicenter collaborative registry. The Western Collaborative Perinatal Group.
Hickok DE, Mills M
Am J Obstet Gynecol 1992 Jun;166(6 Pt 1):1614-7; discussion 1617-8. doi: 10.1016/0002-9378(92)91550-t. PMID: 1615968

Therapy

Percutaneous umbilical blood sampling: results from a multicenter collaborative registry. The Western Collaborative Perinatal Group.
Hickok DE, Mills M
Am J Obstet Gynecol 1992 Jun;166(6 Pt 1):1614-7; discussion 1617-8. doi: 10.1016/0002-9378(92)91550-t. PMID: 1615968

Prognosis

Relationship between maternal antibody type and antenatal course following intrauterine transfusion for red cell alloimmunisation.
Walsh CA, Russell N, McAuliffe FM, Higgins S, Mahony R, Carroll S, McParland P
Eur J Obstet Gynecol Reprod Biol 2013 Dec;171(2):235-9. Epub 2013 Sep 8 doi: 10.1016/j.ejogrb.2013.09.002. PMID: 24075591

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