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Masked Near-Haploidy

MedGen UID:
821930
•Concept ID:
C3829182
•
Cell or Molecular Dysfunction

Definition

A chromosomal abnormality in which a near-haploid cell line is masked by a co-existing hyperdiploid line. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMasked Near-Haploidy

Recent clinical studies

Etiology

Adult Low-Hypodiploid Acute B-Lymphoblastic Leukemia With IKZF3 Deletion and TP53 Mutation: Comparison With Pediatric Patients.
Fang M, Becker PS, Linenberger M, Eaton KD, Appelbaum FR, Dreyer Z, Airewele G, Redell M, Lopez-Terrada D, Patel A, Rabin KR, Lu X
Am J Clin Pathol 2015 Aug;144(2):263-70. doi: 10.1309/AJCPW83OXPYKPEEN. PMID: 26185311
Near haploid childhood acute lymphoblastic leukemia masked by hyperdiploid line: detection by fluorescence in situ hybridization.
Stark B, Jeison M, Gobuzov R, Krug H, Glaser-Gabay L, Luria D, El-Hasid R, Harush MB, Avrahami G, Fisher S, Stein J, Zaizov R, Yaniv I
Cancer Genet Cytogenet 2001 Jul 15;128(2):108-13. doi: 10.1016/s0165-4608(01)00411-3. PMID: 11463448

Diagnosis

Near haploid childhood acute lymphoblastic leukemia masked by hyperdiploid line: detection by fluorescence in situ hybridization.
Stark B, Jeison M, Gobuzov R, Krug H, Glaser-Gabay L, Luria D, El-Hasid R, Harush MB, Avrahami G, Fisher S, Stein J, Zaizov R, Yaniv I
Cancer Genet Cytogenet 2001 Jul 15;128(2):108-13. doi: 10.1016/s0165-4608(01)00411-3. PMID: 11463448

Prognosis

Adult Low-Hypodiploid Acute B-Lymphoblastic Leukemia With IKZF3 Deletion and TP53 Mutation: Comparison With Pediatric Patients.
Fang M, Becker PS, Linenberger M, Eaton KD, Appelbaum FR, Dreyer Z, Airewele G, Redell M, Lopez-Terrada D, Patel A, Rabin KR, Lu X
Am J Clin Pathol 2015 Aug;144(2):263-70. doi: 10.1309/AJCPW83OXPYKPEEN. PMID: 26185311
Near haploid childhood acute lymphoblastic leukemia masked by hyperdiploid line: detection by fluorescence in situ hybridization.
Stark B, Jeison M, Gobuzov R, Krug H, Glaser-Gabay L, Luria D, El-Hasid R, Harush MB, Avrahami G, Fisher S, Stein J, Zaizov R, Yaniv I
Cancer Genet Cytogenet 2001 Jul 15;128(2):108-13. doi: 10.1016/s0165-4608(01)00411-3. PMID: 11463448

Clinical prediction guides

Near haploid childhood acute lymphoblastic leukemia masked by hyperdiploid line: detection by fluorescence in situ hybridization.
Stark B, Jeison M, Gobuzov R, Krug H, Glaser-Gabay L, Luria D, El-Hasid R, Harush MB, Avrahami G, Fisher S, Stein J, Zaizov R, Yaniv I
Cancer Genet Cytogenet 2001 Jul 15;128(2):108-13. doi: 10.1016/s0165-4608(01)00411-3. PMID: 11463448

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