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Delayed Nausea and Vomiting

MedGen UID:
823293
•Concept ID:
C3830545
•
Finding

Definition

Nausea and vomiting occurring more than 24 hours following chemotherapy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDelayed Nausea and Vomiting

Professional guidelines

PubMed

Management of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients.
Navari RM
Paediatr Drugs 2017 Jun;19(3):213-222. doi: 10.1007/s40272-017-0228-2. PMID: 28447301
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood.
Phillips RS, Gopaul S, Gibson F, Houghton E, Craig JV, Light K, Pizer B
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007786. doi: 10.1002/14651858.CD007786.pub2. PMID: 20824866

Recent clinical studies

Etiology

Effects of PC6 acupressure on acute and delayed nausea and vomiting induced by chemotherapy in patients with malignant neoplasm: a meta-analysis.
Xiao C, Qin M, Xia H, Xing Q, Wang D, Qian W
Support Care Cancer 2023 Aug 7;31(9):510. doi: 10.1007/s00520-023-07976-0. PMID: 37548707
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Chemotherapy-induced nausea and vomiting: which antiemetic for which therapy?
Schwartzberg LS
Oncology (Williston Park) 2007 Jul;21(8):946-53; discussion 954, 959, 962 passim. PMID: 17715696
Aprepitant for chemotherapy-induced nausea and vomiting.
Flemm LA
Clin J Oncol Nurs 2004 Jun;8(3):303-6. doi: 10.1188/04.CJON.303-306. PMID: 15208824

Diagnosis

Budget impact of netupitant/palonosetron for the prevention of chemotherapy-induced nausea and vomiting.
Park SH, Binder G, Corman S, Botteman M
J Med Econ 2019 Aug;22(8):840-847. Epub 2019 Jun 11 doi: 10.1080/13696998.2019.1620244. PMID: 31094589
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood.
Phillips RS, Gopaul S, Gibson F, Houghton E, Craig JV, Light K, Pizer B
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007786. doi: 10.1002/14651858.CD007786.pub2. PMID: 20824866
Serotonin receptor antagonists for highly emetogenic chemotherapy in adults.
Billio A, Morello E, Clarke MJ
Cochrane Database Syst Rev 2010 Jan 20;(1):CD006272. doi: 10.1002/14651858.CD006272.pub2. PMID: 20091591

Therapy

Management of Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients.
Navari RM
Paediatr Drugs 2017 Jun;19(3):213-222. doi: 10.1007/s40272-017-0228-2. PMID: 28447301
Rolapitant for the prevention of delayed nausea and vomiting over initial and repeat courses of emetogenic chemotherapy.
Rapoport B, van Eeden R, Smit T
Expert Rev Clin Pharmacol 2017 Jan;10(1):17-29. Epub 2016 Dec 15 doi: 10.1080/17512433.2017.1266251. PMID: 27894202
New treatments on the horizon for chemoradiotherapy-induced nausea and vomiting.
Ruhlmann CH, Herrstedt J
Expert Opin Pharmacother 2016 Aug;17(12):1623-9. Epub 2016 Jun 27 doi: 10.1080/14656566.2016.1202923. PMID: 27322893
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Chemotherapy-induced nausea and vomiting: which antiemetic for which therapy?
Schwartzberg LS
Oncology (Williston Park) 2007 Jul;21(8):946-53; discussion 954, 959, 962 passim. PMID: 17715696

Prognosis

Prevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)-a systematic review and individual patient data meta-analysis.
Chow R, Yin LB, Baqri W, Huang R, Boldt G, Younus J, Lock M, Prsic E, Zimmermann C, Herrstedt J
Support Care Cancer 2023 Aug 3;31(8):505. doi: 10.1007/s00520-023-07978-y. PMID: 37535218
Rolapitant for the prevention of delayed nausea and vomiting over initial and repeat courses of emetogenic chemotherapy.
Rapoport B, van Eeden R, Smit T
Expert Rev Clin Pharmacol 2017 Jan;10(1):17-29. Epub 2016 Dec 15 doi: 10.1080/17512433.2017.1266251. PMID: 27894202
New treatments on the horizon for chemoradiotherapy-induced nausea and vomiting.
Ruhlmann CH, Herrstedt J
Expert Opin Pharmacother 2016 Aug;17(12):1623-9. Epub 2016 Jun 27 doi: 10.1080/14656566.2016.1202923. PMID: 27322893
Palonosetron: a unique 5-HT3 receptor antagonist indicated for the prevention of acute and delayed chemotherapy-induced nausea and vomiting.
Rubenstein EB
Clin Adv Hematol Oncol 2004 May;2(5):284-9. PMID: 16163194
Aprepitant for chemotherapy-induced nausea and vomiting.
Flemm LA
Clin J Oncol Nurs 2004 Jun;8(3):303-6. doi: 10.1188/04.CJON.303-306. PMID: 15208824

Clinical prediction guides

Prevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)-a systematic review and individual patient data meta-analysis.
Chow R, Yin LB, Baqri W, Huang R, Boldt G, Younus J, Lock M, Prsic E, Zimmermann C, Herrstedt J
Support Care Cancer 2023 Aug 3;31(8):505. doi: 10.1007/s00520-023-07978-y. PMID: 37535218
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Waqar SN, Mann J, Baggstrom MQ, Waqar MA, Chitneni P, Williams K, Gao F, Morgensztern D, Govindan R
Acta Oncol 2016 Jun;55(6):700-4. Epub 2016 May 4 doi: 10.3109/0284186X.2016.1154603. PMID: 27145068Free PMC Article
Olanzapine for preventing nausea and vomiting induced by moderately and highly emetogenic chemotherapy.
Wang SY, Yang ZJ, Zhang L
Asian Pac J Cancer Prev 2014;15(22):9587-92. doi: 10.7314/apjcp.2014.15.22.9587. PMID: 25520071
Medicinal plants as antiemetics in the treatment of cancer: a review.
Haniadka R, Popouri S, Palatty PL, Arora R, Baliga MS
Integr Cancer Ther 2012 Mar;11(1):18-28. Epub 2011 Aug 5 doi: 10.1177/1534735411413266. PMID: 21821652
5-HT3 receptor antagonists for the prevention of chemotherapy-induced nausea and vomiting. A comparison of their pharmacology and clinical efficacy.
Gregory RE, Ettinger DS
Drugs 1998 Feb;55(2):173-89. doi: 10.2165/00003495-199855020-00002. PMID: 9506240

Recent systematic reviews

Prevalence and predictors of long-delayed (> 120 h) chemotherapy-induced nausea and vomiting (CINV)-a systematic review and individual patient data meta-analysis.
Chow R, Yin LB, Baqri W, Huang R, Boldt G, Younus J, Lock M, Prsic E, Zimmermann C, Herrstedt J
Support Care Cancer 2023 Aug 3;31(8):505. doi: 10.1007/s00520-023-07978-y. PMID: 37535218
2016 Updated MASCC/ESMO Consensus Recommendations: Prevention of Nausea and Vomiting Following High Emetic Risk Chemotherapy.
Herrstedt J, Roila F, Warr D, Celio L, Navari RM, Hesketh PJ, Chan A, Aapro MS
Support Care Cancer 2017 Jan;25(1):277-288. Epub 2016 Jul 22 doi: 10.1007/s00520-016-3313-0. PMID: 27443154
Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood.
Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B
Cochrane Database Syst Rev 2016 Feb 2;2(2):CD007786. doi: 10.1002/14651858.CD007786.pub3. PMID: 26836199Free PMC Article
Prophylaxis of radiation-induced nausea and vomiting using 5-hydroxytryptamine-3 serotonin receptor antagonists: a systematic review of randomized trials.
Salvo N, Doble B, Khan L, Amirthevasar G, Dennis K, Pasetka M, Deangelis C, Tsao M, Chow E
Int J Radiat Oncol Biol Phys 2012 Jan 1;82(1):408-17. Epub 2010 Nov 13 doi: 10.1016/j.ijrobp.2010.08.060. PMID: 21075553
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood.
Phillips RS, Gopaul S, Gibson F, Houghton E, Craig JV, Light K, Pizer B
Cochrane Database Syst Rev 2010 Sep 8;(9):CD007786. doi: 10.1002/14651858.CD007786.pub2. PMID: 20824866

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