U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hybrid Nerve Sheath Tumor

MedGen UID:
825278
•Concept ID:
C3839433
•
Neoplastic Process
Synonyms: Hybrid Nerve Sheath Neoplasm; Hybrid nerve sheath tumor; Hybrid Neurofibroma-Perineurioma; Hybrid Neurofibroma-Schwannoma; Hybrid Schwannoma-Perineurioma; Nerve Sheath Tumor, NOS; Nerve Sheath Tumor, Not Otherwise Specified
SNOMED CT: Hybrid nerve sheath tumor (703710008)

Definition

A benign nerve sheath tumor characterized by the combination of histologic features seen in schwannomas, neurofibromas, and perineuriomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHybrid Nerve Sheath Tumor

Professional guidelines

PubMed

Assessment of H3K27me3 immunohistochemistry and combination of NF1 and p16 deletions by fluorescence in situ hybridization in the differential diagnosis of malignant peripheral nerve sheath tumor and its histological mimics.
Sugita S, Aoyama T, Emori M, Kido T, Takenami T, Sakuraba K, Terai K, Sugawara T, Tsujiwaki M, Hasegawa T
Diagn Pathol 2021 Aug 30;16(1):79. doi: 10.1186/s13000-021-01140-0. PMID: 34461930Free PMC Article
Surgical management of peripheral nerve sheath tumours in children, with special consideration of neurofibromatoses.
Zipfel J, Al-Hariri M, Gugel I, Haas-Lude K, Grimm A, Warmann S, Krimmel M, Mautner VF, Tatagiba M, Schuhmann MU
Childs Nerv Syst 2020 Oct;36(10):2433-2442. Epub 2020 Jun 6 doi: 10.1007/s00381-020-04703-6. PMID: 32506255Free PMC Article
Gastrointestinal stromal tumors--definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis.
Miettinen M, Lasota J
Virchows Arch 2001 Jan;438(1):1-12. doi: 10.1007/s004280000338. PMID: 11213830

Recent clinical studies

Diagnosis

Intramuscular Hybrid Nerve Sheath Tumor of the Thigh: Case Report and Literature Review.
Chijiiwa Y, Sano J, Okamura K, Nishio J
In Vivo 2024 Mar-Apr;38(2):971-974. doi: 10.21873/invivo.13529. PMID: 38418131Free PMC Article
Benign peripheral nerve sheath tumors: an interdisciplinary diagnostic and therapeutic challenge.
Uerschels AK, Dengler NF, Chihi M, Lenkeit A, Dinger TF, Jabbarli R, Sure U, Hagenacker T, Wrede KH, Gembruch O
Neurosurg Rev 2023 Aug 18;46(1):205. doi: 10.1007/s10143-023-02107-z. PMID: 37594583Free PMC Article
Primary intraosseous hybrid nerve sheath tumor of femur: a hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture.
Chow LT
Pathol Res Pract 2015 May;211(5):409-14. Epub 2014 Nov 14 doi: 10.1016/j.prp.2014.10.014. PMID: 25466465

Prognosis

Trigeminal hybrid nerve sheath tumor - a case report and literature review.
Goyal-Honavar A, Gupta A, Chacko G, Chacko AG
Br J Neurosurg 2023 Oct;37(5):1326-1329. Epub 2021 Jun 20 doi: 10.1080/02688697.2020.1867061. PMID: 34151661

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...