U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Delusional disorder

MedGen UID:
8276
•Concept ID:
C0011251
•
Mental or Behavioral Dysfunction
Synonyms: Delusional Disorder; Delusional Disorders; Disorder, Delusional; Disorders, Delusional
SNOMED CT: Delusional disorder (48500005)
 
Monarch Initiative: MONDO:0004359

Definition

A disorder characterized by the presence of one or more nonbizarre delusions that persist for at least 1 month; the delusion(s) are not due to schizophrenia or a mood disorder, and do not impair psychosocial functioning apart from the ramifications of the delusion(s). [from NCI]

Professional guidelines

PubMed

Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
Fischer CE, Namasivayam A, Crawford-Holland L, Hakobyan N, Schweizer TA, Munoz DG, Pollock BG
Psychiatr Clin North Am 2022 Dec;45(4):691-705. Epub 2022 Oct 14 doi: 10.1016/j.psc.2022.07.001. PMID: 36396273
Delusional infestation: Clinical presentations, diagnosis, and management.
Torales J, García O, Barrios I, O'Higgins M, Castaldelli-Maia JM, Ventriglio A, Jafferany M
J Cosmet Dermatol 2020 Dec;19(12):3183-3188. Epub 2020 Oct 24 doi: 10.1111/jocd.13786. PMID: 33098221
Delusional Parasitosis: Diagnosis and Treatment.
Mumcuoglu KY, Leibovici V, Reuveni I, Bonne O
Isr Med Assoc J 2018 Jul;20(7):456-460. PMID: 30109800

Recent clinical studies

Etiology

Occupational therapy interventions for adults with severe mental illness: a scoping review.
Rocamora-Montenegro M, Compañ-Gabucio LM, Garcia de la Hera M
BMJ Open 2021 Oct 29;11(10):e047467. doi: 10.1136/bmjopen-2020-047467. PMID: 34716157Free PMC Article
A Contagious Disorder: Folie à Deux and Dementia.
Cipriani G, Abdel-Gawad N, Danti S, Di Fiorino M
Am J Alzheimers Dis Other Demen 2018 Nov;33(7):415-422. Epub 2018 May 17 doi: 10.1177/1533317518772060. PMID: 29772920Free PMC Article
Antipsychotic drugs versus cognitive behavioural therapy versus a combination of both in people with psychosis: a randomised controlled pilot and feasibility study.
Morrison AP, Law H, Carter L, Sellers R, Emsley R, Pyle M, French P, Shiers D, Yung AR, Murphy EK, Holden N, Steele A, Bowe SE, Palmier-Claus J, Brooks V, Byrne R, Davies L, Haddad PM
Lancet Psychiatry 2018 May;5(5):411-423. Epub 2018 Apr 5 doi: 10.1016/S2215-0366(18)30096-8. PMID: 29605187Free PMC Article
Treatments for delusional disorder.
Skelton M, Khokhar WA, Thacker SP
Cochrane Database Syst Rev 2015 May 22;2015(5):CD009785. doi: 10.1002/14651858.CD009785.pub2. PMID: 25997589Free PMC Article
Stalking by females.
Carabellese F, La Tegola D, Alfarano E, Tamma M, Candelli C, Catanesi R
Med Sci Law 2013 Jul;53(3):123-31. Epub 2013 Jun 12 doi: 10.1177/0025802413477397. PMID: 23761433

Diagnosis

Overview of late-onset psychoses.
Devanand DP, Jeste DV, Stroup TS, Goldberg TE
Int Psychogeriatr 2024 Jan;36(1):28-42. Epub 2023 Mar 3 doi: 10.1017/S1041610223000157. PMID: 36866576
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
Fischer CE, Namasivayam A, Crawford-Holland L, Hakobyan N, Schweizer TA, Munoz DG, Pollock BG
Psychiatr Clin North Am 2022 Dec;45(4):691-705. Epub 2022 Oct 14 doi: 10.1016/j.psc.2022.07.001. PMID: 36396273
Delusional infestation: Clinical presentations, diagnosis, and management.
Torales J, García O, Barrios I, O'Higgins M, Castaldelli-Maia JM, Ventriglio A, Jafferany M
J Cosmet Dermatol 2020 Dec;19(12):3183-3188. Epub 2020 Oct 24 doi: 10.1111/jocd.13786. PMID: 33098221
Delusional Parasitosis: Diagnosis and Treatment.
Mumcuoglu KY, Leibovici V, Reuveni I, Bonne O
Isr Med Assoc J 2018 Jul;20(7):456-460. PMID: 30109800
Delusional infestation.
Freudenmann RW, Lepping P
Clin Microbiol Rev 2009 Oct;22(4):690-732. doi: 10.1128/CMR.00018-09. PMID: 19822895Free PMC Article

Therapy

Overview of late-onset psychoses.
Devanand DP, Jeste DV, Stroup TS, Goldberg TE
Int Psychogeriatr 2024 Jan;36(1):28-42. Epub 2023 Mar 3 doi: 10.1017/S1041610223000157. PMID: 36866576
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
Fischer CE, Namasivayam A, Crawford-Holland L, Hakobyan N, Schweizer TA, Munoz DG, Pollock BG
Psychiatr Clin North Am 2022 Dec;45(4):691-705. Epub 2022 Oct 14 doi: 10.1016/j.psc.2022.07.001. PMID: 36396273
Occupational therapy interventions for adults with severe mental illness: a scoping review.
Rocamora-Montenegro M, Compañ-Gabucio LM, Garcia de la Hera M
BMJ Open 2021 Oct 29;11(10):e047467. doi: 10.1136/bmjopen-2020-047467. PMID: 34716157Free PMC Article
Delusional Parasitosis: Diagnosis and Treatment.
Mumcuoglu KY, Leibovici V, Reuveni I, Bonne O
Isr Med Assoc J 2018 Jul;20(7):456-460. PMID: 30109800
Using antipsychotic agents in older patients.
Alexopoulos GS, Streim J, Carpenter D, Docherty JP; Expert Consensus Panel for Using Antipsychotic Drugs in Older Patients
J Clin Psychiatry 2004;65 Suppl 2:5-99; discussion 100-102; quiz 103-4. PMID: 14994733

Prognosis

Overview of late-onset psychoses.
Devanand DP, Jeste DV, Stroup TS, Goldberg TE
Int Psychogeriatr 2024 Jan;36(1):28-42. Epub 2023 Mar 3 doi: 10.1017/S1041610223000157. PMID: 36866576
Functional and clinical outcomes of delusional disorder and schizophrenia patients after first episode psychosis: a 4-year follow-up study.
Hui CLM, Chan EWT, Hui PWM, Tao TJ, Ho ECN, Lam BST, Wah See SH, Suen YN, Chang WC, Wa SK, Lee EHM, Chen EYH
BMC Psychiatry 2023 Sep 18;23(1):676. doi: 10.1186/s12888-023-05175-z. PMID: 37723482Free PMC Article
Persistent delusional disorder with delusions of poverty - a case study.
Rodek P, Kucia K
Psychiatr Pol 2023 Oct 31;57(5):995-999. doi: 10.12740/PP/OnlineFirst/143044. PMID: 36370381
The de Clérambault syndrome: more than just a delusional disorder?
Sampogna G, Zinno F, Giallonardo V, Luciano M, Del Vecchio V, Fiorillo A
Int Rev Psychiatry 2020 Aug-Sep;32(5-6):385-390. Epub 2020 Apr 14 doi: 10.1080/09540261.2020.1744536. PMID: 32286086
Cognition and functionality in delusional disorder.
Díaz-Caneja CM, Cervilla JA, Haro JM, Arango C, de Portugal E
Eur Psychiatry 2019 Jan;55:52-60. Epub 2018 Oct 30 doi: 10.1016/j.eurpsy.2018.09.010. PMID: 30388425

Clinical prediction guides

Persistent delusional disorder with delusions of poverty - a case study.
Rodek P, Kucia K
Psychiatr Pol 2023 Oct 31;57(5):995-999. doi: 10.12740/PP/OnlineFirst/143044. PMID: 36370381
Capgras and Fregoli syndromes: delusion and misidentification.
Ventriglio A, Bhugra D, De Berardis D, Torales J, Castaldelli-Maia JM, Fiorillo A
Int Rev Psychiatry 2020 Aug-Sep;32(5-6):391-395. Epub 2020 May 7 doi: 10.1080/09540261.2020.1756625. PMID: 32378427
Cognition and functionality in delusional disorder.
Díaz-Caneja CM, Cervilla JA, Haro JM, Arango C, de Portugal E
Eur Psychiatry 2019 Jan;55:52-60. Epub 2018 Oct 30 doi: 10.1016/j.eurpsy.2018.09.010. PMID: 30388425
Antipsychotic drugs versus cognitive behavioural therapy versus a combination of both in people with psychosis: a randomised controlled pilot and feasibility study.
Morrison AP, Law H, Carter L, Sellers R, Emsley R, Pyle M, French P, Shiers D, Yung AR, Murphy EK, Holden N, Steele A, Bowe SE, Palmier-Claus J, Brooks V, Byrne R, Davies L, Haddad PM
Lancet Psychiatry 2018 May;5(5):411-423. Epub 2018 Apr 5 doi: 10.1016/S2215-0366(18)30096-8. PMID: 29605187Free PMC Article
Using antipsychotic agents in older patients.
Alexopoulos GS, Streim J, Carpenter D, Docherty JP; Expert Consensus Panel for Using Antipsychotic Drugs in Older Patients
J Clin Psychiatry 2004;65 Suppl 2:5-99; discussion 100-102; quiz 103-4. PMID: 14994733

Recent systematic reviews

A systematic review and meta-analysis of suicidality in psychotic disorders: Stratified analyses by psychotic subtypes, clinical setting and geographical region.
Álvarez A, Guàrdia A, González-Rodríguez A, Betriu M, Palao D, Monreal JA, Soria V, Labad J
Neurosci Biobehav Rev 2022 Dec;143:104964. Epub 2022 Nov 17 doi: 10.1016/j.neubiorev.2022.104964. PMID: 36403792
Psychometric instruments for the assessment of depressive symptoms in patients with delusional disorder: A systematic review.
González-Rodríguez A, Monreal JA, Porras-Segovia A, Cervilla JA, Gutiérrez-Rojas L
Psychiatry Res 2022 Apr;310:114435. Epub 2022 Feb 7 doi: 10.1016/j.psychres.2022.114435. PMID: 35150968
A systematic review of antipsychotic agents for primary delusional infestation.
McPhie ML, Kirchhof MG
J Dermatolog Treat 2022 Mar;33(2):709-721. Epub 2020 Jul 22 doi: 10.1080/09546634.2020.1795061. PMID: 32658556
A Systematic Review on the Pharmacological Treatment of Delusional Disorder.
Muñoz-Negro JE, Cervilla JA
J Clin Psychopharmacol 2016 Dec;36(6):684-690. doi: 10.1097/JCP.0000000000000595. PMID: 27811554
Treatments for delusional disorder.
Skelton M, Khokhar WA, Thacker SP
Cochrane Database Syst Rev 2015 May 22;2015(5):CD009785. doi: 10.1002/14651858.CD009785.pub2. PMID: 25997589Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...