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Hemorrhagic complication of pregnancy

MedGen UID:
82845
•Concept ID:
C0269596
•
Pathologic Function
Synonyms: Hemorrhage of pregnancy; Hemorrhagic Complication of Pregnancy
SNOMED CT: Hemorrhagic complication of pregnancy (106004004); Hemorrhage of pregnancy (106004004)

Definition

Bleeding occurring during pregnancy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHemorrhagic complication of pregnancy

Professional guidelines

PubMed

Hypothyroidism: Diagnosis and Treatment.
Wilson SA, Stem LA, Bruehlman RD
Am Fam Physician 2021 May 15;103(10):605-613. PMID: 33983002
ACOG Practice Bulletin No. 190: Gestational Diabetes Mellitus.
Obstet Gynecol 2018 Feb;131(2):e49-e64. doi: 10.1097/AOG.0000000000002501. PMID: 29370047
Practice Bulletin No. 183: Postpartum Hemorrhage.
Committee on Practice Bulletins-Obstetrics
Obstet Gynecol 2017 Oct;130(4):e168-e186. doi: 10.1097/AOG.0000000000002351. PMID: 28937571

Recent clinical studies

Etiology

Hereditary hemorrhagic telangiectasia (HHT): a practical guide to management.
Hammill AM, Wusik K, Kasthuri RS
Hematology Am Soc Hematol Educ Program 2021 Dec 10;2021(1):469-477. doi: 10.1182/hematology.2021000281. PMID: 34889398Free PMC Article
Intrapartum hemorrhage.
Alexander JM, Wortman AC
Obstet Gynecol Clin North Am 2013 Mar;40(1):15-26. doi: 10.1016/j.ogc.2012.12.003. PMID: 23466133
Maternal haemorrhage.
Walfish M, Neuman A, Wlody D
Br J Anaesth 2009 Dec;103 Suppl 1:i47-56. doi: 10.1093/bja/aep303. PMID: 20007990
Obstetric emergencies.
Mirza FG, Gaddipati S
Semin Perinatol 2009 Apr;33(2):97-103. doi: 10.1053/j.semperi.2009.01.003. PMID: 19324238
Diagnosis and management of ovarian cyst accidents.
Bottomley C, Bourne T
Best Pract Res Clin Obstet Gynaecol 2009 Oct;23(5):711-24. Epub 2009 Mar 18 doi: 10.1016/j.bpobgyn.2009.02.001. PMID: 19299205

Diagnosis

Hereditary hemorrhagic telangiectasia (HHT): a practical guide to management.
Hammill AM, Wusik K, Kasthuri RS
Hematology Am Soc Hematol Educ Program 2021 Dec 10;2021(1):469-477. doi: 10.1182/hematology.2021000281. PMID: 34889398Free PMC Article
Foetal and neonatal alloimmune thrombocytopenia.
Winkelhorst D, Oepkes D
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:15-27. Epub 2019 Feb 6 doi: 10.1016/j.bpobgyn.2019.01.017. PMID: 30827816
Intrapartum hemorrhage.
Alexander JM, Wortman AC
Obstet Gynecol Clin North Am 2013 Mar;40(1):15-26. doi: 10.1016/j.ogc.2012.12.003. PMID: 23466133
How to approach thrombocytopenia.
Stasi R
Hematology Am Soc Hematol Educ Program 2012;2012:191-7. doi: 10.1182/asheducation-2012.1.191. PMID: 23233580
Peripartum hemorrhage.
Alamia V Jr, Meyer BA
Obstet Gynecol Clin North Am 1999 Jun;26(2):385-98. doi: 10.1016/s0889-8545(05)70081-4. PMID: 10399768

Therapy

Aspirin Discontinuation at 24 to 28 Weeks' Gestation in Pregnancies at High Risk of Preterm Preeclampsia: A Randomized Clinical Trial.
Mendoza M, Bonacina E, Garcia-Manau P, López M, Caamiña S, Vives À, Lopez-Quesada E, Ricart M, Maroto A, de Mingo L, Pintado E, Ferrer-Costa R, Martin L, Rodríguez-Zurita A, Garcia E, Pallarols M, Vidal-Sagnier L, Teixidor M, Orizales-Lago C, Pérez-Gomez A, Ocaña V, Puerto L, Millán P, Alsius M, Diaz S, Maiz N, Carreras E, Suy A
JAMA 2023 Feb 21;329(7):542-550. doi: 10.1001/jama.2023.0691. PMID: 36809321Free PMC Article
Massive obstetric hemorrhage: Current approach to management.
Guasch E, Gilsanz F
Med Intensiva 2016 Jun-Jul;40(5):298-310. Epub 2016 May 13 doi: 10.1016/j.medin.2016.02.010. PMID: 27184441
How to approach thrombocytopenia.
Stasi R
Hematology Am Soc Hematol Educ Program 2012;2012:191-7. doi: 10.1182/asheducation-2012.1.191. PMID: 23233580
Maternal haemorrhage.
Walfish M, Neuman A, Wlody D
Br J Anaesth 2009 Dec;103 Suppl 1:i47-56. doi: 10.1093/bja/aep303. PMID: 20007990
Essential thrombocythemia.
Finazzi G, Harrison C
Semin Hematol 2005 Oct;42(4):230-8. doi: 10.1053/j.seminhematol.2005.05.022. PMID: 16210036

Prognosis

Epidemiology and definition of PPH worldwide.
Bláha J, Bartošová T
Best Pract Res Clin Anaesthesiol 2022 Dec;36(3-4):325-339. Epub 2022 Nov 13 doi: 10.1016/j.bpa.2022.11.001. PMID: 36513428
Hereditary hemorrhagic telangiectasia (HHT): a practical guide to management.
Hammill AM, Wusik K, Kasthuri RS
Hematology Am Soc Hematol Educ Program 2021 Dec 10;2021(1):469-477. doi: 10.1182/hematology.2021000281. PMID: 34889398Free PMC Article
Major obstetric hemorrhage.
Le Gouez A, Mercier FJ
Transfus Clin Biol 2016 Nov;23(4):229-232. Epub 2016 Aug 31 doi: 10.1016/j.tracli.2016.08.003. PMID: 27592155
Postpartum hemorrhage.
Su CW
Prim Care 2012 Mar;39(1):167-87. doi: 10.1016/j.pop.2011.11.009. PMID: 22309588
Peripartum hemorrhage.
Alamia V Jr, Meyer BA
Obstet Gynecol Clin North Am 1999 Jun;26(2):385-98. doi: 10.1016/s0889-8545(05)70081-4. PMID: 10399768

Clinical prediction guides

Prevalence and risk factors of severe postpartum hemorrhage: a retrospective cohort study.
Liu CN, Yu FB, Xu YZ, Li JS, Guan ZH, Sun MN, Liu CA, He F, Chen DJ
BMC Pregnancy Childbirth 2021 Apr 26;21(1):332. doi: 10.1186/s12884-021-03818-1. PMID: 33902475Free PMC Article
Predicting risk of postpartum haemorrhage: a systematic review.
Neary C, Naheed S, McLernon DJ, Black M
BJOG 2021 Jan;128(1):46-53. Epub 2020 Aug 5 doi: 10.1111/1471-0528.16379. PMID: 32575159
Pregnancy and delivery in women with von Willebrand disease.
Castaman G, James PD
Eur J Haematol 2019 Aug;103(2):73-79. Epub 2019 May 31 doi: 10.1111/ejh.13250. PMID: 31107984Free PMC Article
Cell Salvage in Obstetrics.
Goucher H, Wong CA, Patel SK, Toledo P
Anesth Analg 2015 Aug;121(2):465-8. doi: 10.1213/ANE.0000000000000786. PMID: 26197375
Peripartum hemorrhage.
Alamia V Jr, Meyer BA
Obstet Gynecol Clin North Am 1999 Jun;26(2):385-98. doi: 10.1016/s0889-8545(05)70081-4. PMID: 10399768

Recent systematic reviews

Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis.
Ye W, Luo C, Huang J, Li C, Liu Z, Liu F
BMJ 2022 May 25;377:e067946. doi: 10.1136/bmj-2021-067946. PMID: 35613728Free PMC Article
Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis.
Omotayo MO, Abioye AI, Kuyebi M, Eke AC
J Obstet Gynaecol Res 2021 Aug;47(8):2565-2576. Epub 2021 May 17 doi: 10.1111/jog.14834. PMID: 34002432Free PMC Article
Risk Factors for Atonic Postpartum Hemorrhage: A Systematic Review and Meta-analysis.
Ende HB, Lozada MJ, Chestnut DH, Osmundson SS, Walden RL, Shotwell MS, Bauchat JR
Obstet Gynecol 2021 Feb 1;137(2):305-323. doi: 10.1097/AOG.0000000000004228. PMID: 33417319Free PMC Article
Headache and pregnancy: a systematic review.
Negro A, Delaruelle Z, Ivanova TA, Khan S, Ornello R, Raffaelli B, Terrin A, Reuter U, Mitsikostas DD; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2017 Oct 19;18(1):106. doi: 10.1186/s10194-017-0816-0. PMID: 29052046Free PMC Article
Global causes of maternal death: a WHO systematic analysis.
Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels J, Gülmezoglu AM, Temmerman M, Alkema L
Lancet Glob Health 2014 Jun;2(6):e323-33. Epub 2014 May 5 doi: 10.1016/S2214-109X(14)70227-X. PMID: 25103301

Supplemental Content

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