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Epidural abscess

MedGen UID:
82848
Concept ID:
C0270629
Disease or Syndrome
Synonyms: Abscess, Epidural; Abscess, Extradural; Epidural Abscess; Extradural Abscess
SNOMED CT: Epidural abscess (61974008); Extradural abscess (61974008)
 
Monarch Initiative: MONDO:0005752

Definition

Circumscribed collections of suppurative material occurring in the spinal or intracranial epidural space. The majority of epidural abscesses occur in the spinal canal and are associated with osteomyelitis of a vertebral body; analgesia, epidural; and other conditions. Clinical manifestations include local and radicular pain, weakness, sensory loss, urinary incontinence, and fecal incontinence. Cranial epidural abscesses are usually associated with osteomyelitis of a cranial bone, sinusitis, or otitis media. (From Adams et al., Principles of Neurology, 6th ed, p710 and pp1240-1; J Neurol Neurosurg Psychiatry 1998 Aug;65(2):209-12) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEpidural abscess

Professional guidelines

PubMed

Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
David MZ, Daum RS
Curr Top Microbiol Immunol 2017;409:325-383. doi: 10.1007/82_2017_42. PMID: 28900682

Recent clinical studies

Etiology

Kuris EO, McDonald CL, Palumbo MA, Daniels AH
Am J Med 2021 Dec;134(12):1483-1489. Epub 2021 Aug 30 doi: 10.1016/j.amjmed.2021.07.021. PMID: 34473966
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Tompkins M, Panuncialman I, Lucas P, Palumbo M
J Emerg Med 2010 Sep;39(3):384-90. Epub 2010 Jan 8 doi: 10.1016/j.jemermed.2009.11.001. PMID: 20060254
Grewal S, Hocking G, Wildsmith JA
Br J Anaesth 2006 Mar;96(3):292-302. Epub 2006 Jan 23 doi: 10.1093/bja/ael006. PMID: 16431882
Tay BK, Deckey J, Hu SS
J Am Acad Orthop Surg 2002 May-Jun;10(3):188-97. doi: 10.5435/00124635-200205000-00005. PMID: 12041940

Diagnosis

Vaphiades MS, Isen D, Tavakoli M, Bilyk JR
Surv Ophthalmol 2023 Jul-Aug;68(4):830-833. Epub 2022 Nov 23 doi: 10.1016/j.survophthal.2022.11.005. PMID: 36427561
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Ropper AE, Ropper AH
N Engl J Med 2017 Apr 6;376(14):1358-1369. doi: 10.1056/NEJMra1516539. PMID: 28379788
Bonfield CM, Sharma J, Dobson S
J Infect 2015 Jun;71 Suppl 1:S42-6. Epub 2015 Apr 24 doi: 10.1016/j.jinf.2015.04.012. PMID: 25917804
Darouiche RO
N Engl J Med 2006 Nov 9;355(19):2012-20. doi: 10.1056/NEJMra055111. PMID: 17093252

Therapy

Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Babic M, Simpfendorfer CS, Berbari EF
Curr Opin Infect Dis 2019 Jun;32(3):265-271. doi: 10.1097/QCO.0000000000000544. PMID: 31021957
Tompkins M, Panuncialman I, Lucas P, Palumbo M
J Emerg Med 2010 Sep;39(3):384-90. Epub 2010 Jan 8 doi: 10.1016/j.jemermed.2009.11.001. PMID: 20060254
Darouiche RO
N Engl J Med 2006 Nov 9;355(19):2012-20. doi: 10.1056/NEJMra055111. PMID: 17093252
Grewal S, Hocking G, Wildsmith JA
Br J Anaesth 2006 Mar;96(3):292-302. Epub 2006 Jan 23 doi: 10.1093/bja/ael006. PMID: 16431882

Prognosis

Wildenthal JA, Atkinson A, Lewis S, Sayood S, Nolan NS, Cabrera NL, Marschall J, Durkin MJ, Marks LR
Clin Infect Dis 2023 Feb 8;76(3):487-496. doi: 10.1093/cid/ciac714. PMID: 36052413Free PMC Article
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Babic M, Simpfendorfer CS, Berbari EF
Curr Opin Infect Dis 2019 Jun;32(3):265-271. doi: 10.1097/QCO.0000000000000544. PMID: 31021957
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
Cheung WY, Luk KD
Int Orthop 2012 Feb;36(2):397-404. Epub 2011 Oct 28 doi: 10.1007/s00264-011-1384-6. PMID: 22033610Free PMC Article

Clinical prediction guides

Hsieh YL, Chen HY, Lin CR, Wang CF
Pain Pract 2023 Nov;23(8):956-969. Epub 2023 Jul 16 doi: 10.1111/papr.13273. PMID: 37455298
Schwab JH, Shah AA
J Am Acad Orthop Surg 2020 Nov 1;28(21):e929-e938. doi: 10.5435/JAAOS-D-19-00685. PMID: 32694325
Babic M, Simpfendorfer CS, Berbari EF
Curr Opin Infect Dis 2019 Jun;32(3):265-271. doi: 10.1097/QCO.0000000000000544. PMID: 31021957
Diaz I, Bamberger DM
Semin Respir Infect 1995 Mar;10(1):14-20. PMID: 7761709
Baker AS, Ojemann RG, Swartz MN, Richardson EP Jr
N Engl J Med 1975 Sep 4;293(10):463-8. doi: 10.1056/NEJM197509042931001. PMID: 1152860

Recent systematic reviews

Hsieh YL, Chen HY, Lin CR, Wang CF
Pain Pract 2023 Nov;23(8):956-969. Epub 2023 Jul 16 doi: 10.1111/papr.13273. PMID: 37455298
Galliker G, Scherer DE, Trippolini MA, Rasmussen-Barr E, LoMartire R, Wertli MM
Am J Med 2020 Jan;133(1):60-72.e14. Epub 2019 Jul 3 doi: 10.1016/j.amjmed.2019.06.005. PMID: 31278933
Alerhand S, Wood S, Long B, Koyfman A
Intern Emerg Med 2017 Dec;12(8):1179-1183. Epub 2017 Aug 4 doi: 10.1007/s11739-017-1718-5. PMID: 28779448
Suppiah S, Meng Y, Fehlings MG, Massicotte EM, Yee A, Shamji MF
World Neurosurg 2016 Sep;93:20-8. Epub 2016 Jun 1 doi: 10.1016/j.wneu.2016.05.074. PMID: 27262655
Arko L 4th, Quach E, Nguyen V, Chang D, Sukul V, Kim BS
Neurosurg Focus 2014 Aug;37(2):E4. doi: 10.3171/2014.6.FOCUS14127. PMID: 25081964

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