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Infection by Opisthorchis viverrini

MedGen UID:
82917
•Concept ID:
C0277005
•
Disease or Syndrome
Synonyms: Infection, Opisthorchis viverrini; Infections, Opisthorchis viverrini; Opisthorchis viverrini Infection; Opisthorchis viverrini Infections
SNOMED CT: Infection by Opisthorchis viverrini (90281006); Infection caused by Opisthorchis viverrini (90281006)

Definition

An infection caused by the parasite Opisthorchis viverrini. It results from the ingestion of raw or undercooked food. The clinical features vary from mild to severe and include gastrointestinal symptoms, anorexia, weight loss, hepatomegaly, and cholangitis. Patients are at an increased risk of developing cholangiocarcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfection by Opisthorchis viverrini

Professional guidelines

PubMed

Clonorchiasis and opisthorchiasis: epidemiology, transmission, clinical features, morbidity, diagnosis, treatment, and control.
Qian M-B, Keiser J, Utzinger J, Zhou X-N
Clin Microbiol Rev 2024 Mar 14;37(1):e0000923. Epub 2024 Jan 3 doi: 10.1128/cmr.00009-23. PMID: 38169283Free PMC Article
Reinfection by Opisthorchis Viverrini after Treatment with Praziquantel.
Saengsawang P, Promthet S, Bradshaw P
Asian Pac J Cancer Prev 2016;17(2):857-62. doi: 10.7314/apjcp.2016.17.2.857. PMID: 26925692
Risk biomarkers for assessment and chemoprevention of liver fluke-associated cholangiocarcinoma.
Yongvanit P, Pinlaor S, Loilome W
J Hepatobiliary Pancreat Sci 2014 May;21(5):309-15. Epub 2014 Jan 10 doi: 10.1002/jhbp.63. PMID: 24408859

Recent clinical studies

Etiology

Prevalence and Risk Factors for Infection by Opisthorchis viverrini in an Urban Area of Mahasarakham Province, Northeast Thailand.
Chaiputcha K, Promthet S, Bradshaw P
Asian Pac J Cancer Prev 2015;16(10):4173-6. doi: 10.7314/apjcp.2015.16.10.4173. PMID: 26028068
High excretion of etheno adducts in liver fluke-infected patients: protection by praziquantel against DNA damage.
Dechakhamphu S, Yongvanit P, Nair J, Pinlaor S, Sitthithaworn P, Bartsch H
Cancer Epidemiol Biomarkers Prev 2008 Jul;17(7):1658-64. doi: 10.1158/1055-9965.EPI-08-0191. PMID: 18628417
The role of infection by Opisthorchis viverrini, hepatitis B virus, and aflatoxin exposure in the etiology of liver cancer in Thailand. A correlation study.
Srivatanakul P, Parkin DM, Jiang YZ, Khlat M, Kao-Ian UT, Sontipong S, Wild C
Cancer 1991 Dec 1;68(11):2411-7. doi: 10.1002/1097-0142(19911201)68:11<2411::aid-cncr2820681114>3.0.co;2-0. PMID: 1657355

Therapy

The role of infection by Opisthorchis viverrini, hepatitis B virus, and aflatoxin exposure in the etiology of liver cancer in Thailand. A correlation study.
Srivatanakul P, Parkin DM, Jiang YZ, Khlat M, Kao-Ian UT, Sontipong S, Wild C
Cancer 1991 Dec 1;68(11):2411-7. doi: 10.1002/1097-0142(19911201)68:11<2411::aid-cncr2820681114>3.0.co;2-0. PMID: 1657355
Rate of re-infection by Opisthorchis viverrini in an endemic northeast Thai community after chemotherapy.
Upatham ES, Viyanant V, Brockelman WY, Kurathong S, Lee P, Kraengraeng R
Int J Parasitol 1988 Jul;18(5):643-9. doi: 10.1016/0020-7519(88)90099-9. PMID: 3170073

Prognosis

Proteomic profile of Bithynia siamensis goniomphalos snails upon infection with the carcinogenic liver fluke Opisthorchis viverrini.
Prasopdee S, Tesana S, Cantacessi C, Laha T, Mulvenna J, Grams R, Loukas A, Sotillo J
J Proteomics 2015 Jan 15;113:281-91. Epub 2014 Oct 2 doi: 10.1016/j.jprot.2014.09.018. PMID: 25284051Free PMC Article
High excretion of etheno adducts in liver fluke-infected patients: protection by praziquantel against DNA damage.
Dechakhamphu S, Yongvanit P, Nair J, Pinlaor S, Sitthithaworn P, Bartsch H
Cancer Epidemiol Biomarkers Prev 2008 Jul;17(7):1658-64. doi: 10.1158/1055-9965.EPI-08-0191. PMID: 18628417
The role of infection by Opisthorchis viverrini, hepatitis B virus, and aflatoxin exposure in the etiology of liver cancer in Thailand. A correlation study.
Srivatanakul P, Parkin DM, Jiang YZ, Khlat M, Kao-Ian UT, Sontipong S, Wild C
Cancer 1991 Dec 1;68(11):2411-7. doi: 10.1002/1097-0142(19911201)68:11<2411::aid-cncr2820681114>3.0.co;2-0. PMID: 1657355

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