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Metastatic melanoma

MedGen UID:
83002
Concept ID:
C0278883
Neoplastic Process
Synonyms: metastatic malignant melanoma; Metastatic Melanoma; metastatic melanoma
 
Monarch Initiative: MONDO:0005191

Definition

A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain. [from NCI]

Professional guidelines

PubMed

Ralli M, Botticelli A, Visconti IC, Angeletti D, Fiore M, Marchetti P, Lambiase A, de Vincentiis M, Greco A
J Immunol Res 2020;2020:9235638. Epub 2020 Jun 28 doi: 10.1155/2020/9235638. PMID: 32671117Free PMC Article
Davis LE, Shalin SC, Tackett AJ
Cancer Biol Ther 2019;20(11):1366-1379. Epub 2019 Aug 1 doi: 10.1080/15384047.2019.1640032. PMID: 31366280Free PMC Article
Champiat S, Lambotte O, Barreau E, Belkhir R, Berdelou A, Carbonnel F, Cauquil C, Chanson P, Collins M, Durrbach A, Ederhy S, Feuillet S, François H, Lazarovici J, Le Pavec J, De Martin E, Mateus C, Michot JM, Samuel D, Soria JC, Robert C, Eggermont A, Marabelle A
Ann Oncol 2016 Apr;27(4):559-74. Epub 2015 Dec 28 doi: 10.1093/annonc/mdv623. PMID: 26715621

Recent clinical studies

Etiology

van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG
J Immunother Cancer 2020 Aug;8(2) doi: 10.1136/jitc-2020-000848. PMID: 32753545Free PMC Article
Pavri SN, Clune J, Ariyan S, Narayan D
Plast Reconstr Surg 2016 Aug;138(2):330e-340e. doi: 10.1097/PRS.0000000000002367. PMID: 27465194
Snyder A, Zamarin D, Wolchok JD
Prog Tumor Res 2015;42:22-9. Epub 2015 Sep 4 doi: 10.1159/000436998. PMID: 26376963
Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH Jr, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD
N Engl J Med 2011 Jun 30;364(26):2517-26. Epub 2011 Jun 5 doi: 10.1056/NEJMoa1104621. PMID: 21639810
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ
N Engl J Med 2010 Aug 19;363(8):711-23. Epub 2010 Jun 5 doi: 10.1056/NEJMoa1003466. PMID: 20525992Free PMC Article

Diagnosis

Lowe L
Pathology 2023 Mar;55(2):236-244. Epub 2022 Dec 21 doi: 10.1016/j.pathol.2022.11.006. PMID: 36641376
Davis LE, Shalin SC, Tackett AJ
Cancer Biol Ther 2019;20(11):1366-1379. Epub 2019 Aug 1 doi: 10.1080/15384047.2019.1640032. PMID: 31366280Free PMC Article
Wick MR
Semin Diagn Pathol 2014 Jan;31(1):53-65. Epub 2013 Dec 25 doi: 10.1053/j.semdp.2013.12.001. PMID: 24680183
Allen BC, Mohammed TL, Tan CD, Miller DV, Williamson EE, Kirsch JS
Curr Probl Diagn Radiol 2012 Sep-Oct;41(5):159-64. doi: 10.1067/j.cpradiol.2011.09.001. PMID: 22818836
Larkin J, Gore M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445806Free PMC Article

Therapy

Hayday A, Dechanet-Merville J, Rossjohn J, Silva-Santos B
Science 2024 Oct 4;386(6717):eabq7248. doi: 10.1126/science.abq7248. PMID: 39361750Free PMC Article
Signorelli J, Shah Gandhi A
Ann Pharmacother 2017 Feb;51(2):146-153. Epub 2016 Oct 4 doi: 10.1177/1060028016672037. PMID: 27701080
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P, Ferrucci PF, Hill A, Wagstaff J, Carlino MS, Haanen JB, Maio M, Marquez-Rodas I, McArthur GA, Ascierto PA, Long GV, Callahan MK, Postow MA, Grossmann K, Sznol M, Dreno B, Bastholt L, Yang A, Rollin LM, Horak C, Hodi FS, Wolchok JD
N Engl J Med 2015 Jul 2;373(1):23-34. Epub 2015 May 31 doi: 10.1056/NEJMoa1504030. PMID: 26027431Free PMC Article
Russell SJ, Peng KW, Bell JC
Nat Biotechnol 2012 Jul 10;30(7):658-70. doi: 10.1038/nbt.2287. PMID: 22781695Free PMC Article
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, O'Day SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li J, Nelson B, Hou J, Lee RJ, Flaherty KT, McArthur GA; BRIM-3 Study Group
N Engl J Med 2011 Jun 30;364(26):2507-16. Epub 2011 Jun 5 doi: 10.1056/NEJMoa1103782. PMID: 21639808Free PMC Article

Prognosis

van den Berg JH, Heemskerk B, van Rooij N, Gomez-Eerland R, Michels S, van Zon M, de Boer R, Bakker NAM, Jorritsma-Smit A, van Buuren MM, Kvistborg P, Spits H, Schotte R, Mallo H, Karger M, van der Hage JA, Wouters MWJM, Pronk LM, Geukes Foppen MH, Blank CU, Beijnen JH, Nuijen B, Schumacher TN, Haanen JBAG
J Immunother Cancer 2020 Aug;8(2) doi: 10.1136/jitc-2020-000848. PMID: 32753545Free PMC Article
Turner N, Ware O, Bosenberg M
Clin Exp Metastasis 2018 Aug;35(5-6):379-391. Epub 2018 May 2 doi: 10.1007/s10585-018-9893-y. PMID: 29722002
Eggermont AM, Spatz A, Robert C
Lancet 2014 Mar 1;383(9919):816-27. Epub 2013 Sep 19 doi: 10.1016/S0140-6736(13)60802-8. PMID: 24054424
Cummins DL, Cummins JM, Pantle H, Silverman MA, Leonard AL, Chanmugam A
Mayo Clin Proc 2006 Apr;81(4):500-7. doi: 10.4065/81.4.500. PMID: 16610570
Sun W, Schuchter LM
Curr Treat Options Oncol 2001 Jun;2(3):193-202. doi: 10.1007/s11864-001-0033-5. PMID: 12057119

Clinical prediction guides

Chen W, He Y, Zhou G, Chen X, Ye Y, Zhang G, Liu H
BMC Med 2024 Jan 17;22(1):24. doi: 10.1186/s12916-023-03175-0. PMID: 38229080Free PMC Article
Serratì S, Guida M, Di Fonte R, De Summa S, Strippoli S, Iacobazzi RM, Quarta A, De Risi I, Guida G, Paradiso A, Porcelli L, Azzariti A
Mol Cancer 2022 Jan 18;21(1):20. doi: 10.1186/s12943-021-01490-9. PMID: 35042524Free PMC Article
Larkin J, Gore M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445806Free PMC Article
Sun W, Schuchter LM
Curr Treat Options Oncol 2001 Jun;2(3):193-202. doi: 10.1007/s11864-001-0033-5. PMID: 12057119
Rosenberg SA, Packard BS, Aebersold PM, Solomon D, Topalian SL, Toy ST, Simon P, Lotze MT, Yang JC, Seipp CA
N Engl J Med 1988 Dec 22;319(25):1676-80. doi: 10.1056/NEJM198812223192527. PMID: 3264384

Recent systematic reviews

Boutros A, Tanda ET, Croce E, Catalano F, Ceppi M, Bruzzone M, Cecchi F, Arecco L, Fraguglia M, Pronzato P, Genova C, Del Mastro L, Lambertini M, Spagnolo F
Eur J Cancer 2023 Jul;188:64-79. Epub 2023 Apr 24 doi: 10.1016/j.ejca.2023.04.010. PMID: 37196485
Peeraphatdit TB, Wang J, Odenwald MA, Hu S, Hart J, Charlton MR
Hepatology 2020 Jul;72(1):315-329. doi: 10.1002/hep.31227. PMID: 32167613
Safa H, Johnson DH, Trinh VA, Rodgers TE, Lin H, Suarez-Almazor ME, Fa'ak F, Saberian C, Yee C, Davies MA, Tummala S, Woodman K, Abdel-Wahab N, Diab A
J Immunother Cancer 2019 Nov 21;7(1):319. doi: 10.1186/s40425-019-0774-y. PMID: 31753014Free PMC Article
Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G
Ann Oncol 2019 Dec 1;30(12):1902-1913. doi: 10.1093/annonc/mdz398. PMID: 31566658
Larkin J, Gore M
BMJ Clin Evid 2008 Aug 22;2008 PMID: 19445806Free PMC Article

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