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Dentigerous cyst

MedGen UID:
8309
•Concept ID:
C0011428
•
Disease or Syndrome
Synonyms: Cyst, Dentigerous; Cysts, Dentigerous; Dentigerous Cyst; Dentigerous Cysts
SNOMED CT: Dentigerous cyst (9245008); Dentigerous cyst of jaw (9245008); Dentigerous odontogenic cyst (9245008); Follicular cyst of jaw (9245008)
 
Monarch Initiative: MONDO:0020815

Definition

An odontogenic cyst that is attached to the cervical region of an unerupted tooth and envelops the crown. (WHO 2017) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDentigerous cyst

Professional guidelines

PubMed

Cystic Lesions of the Jaws: The Top 10 Differential Diagnoses to Ponder.
McLean AC, Vargas PA
Head Neck Pathol 2023 Mar;17(1):85-98. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01525-1. PMID: 36928736Free PMC Article
Assessment of Hounsfield unit in the differential diagnosis of odontogenic cysts.
Uehara K, Hisatomi M, Munhoz L, Kawazu T, Yanagi Y, Okada S, Takeshita Y, Saito EA, Asaumi J
Dentomaxillofac Radiol 2021 Feb 1;50(2):20200188. Epub 2020 Aug 12 doi: 10.1259/dmfr.20200188. PMID: 32783633Free PMC Article
DIFFICULTIES IN DIFFERENTIAL DIAGNOSIS OF CERTAIN OSTEOLYTIC LESIONS OF THE MANDIBLE.
SCHREIBER LK
Oral Surg Oral Med Oral Pathol 1965 Sep;20:407-14. doi: 10.1016/0030-4220(65)90175-1. PMID: 14342935

Recent clinical studies

Etiology

Odontogenic Cysts.
Rajendra Santosh AB
Dent Clin North Am 2020 Jan;64(1):105-119. Epub 2019 Oct 18 doi: 10.1016/j.cden.2019.08.002. PMID: 31735221
Relevance of periodic evaluation of endodontically treated primary teeth.
Kamal El-Din Mohamed S, Abutayyem H, Abdelnabi S, Alkhabuli J
Libyan J Med 2019 Dec;14(1):1643208. doi: 10.1080/19932820.2019.1643208. PMID: 31339472Free PMC Article
Genetic basis of dentigerous cysts associated with supernumerary teeth: A narrative review.
Anthonappa RP, Ekambaram M, Neboda CNG, King NM, Rabie AM
J Investig Clin Dent 2018 Feb;9(1) Epub 2017 Apr 6 doi: 10.1111/jicd.12267. PMID: 28387048
Odontogenic lesions in pediatric patients.
Fang QG, Shi S, Sun CF
J Craniofac Surg 2014 May;25(3):e248-51. doi: 10.1097/SCS.0000000000000548. PMID: 24785745
Odontogenic cysts. A clinicopathological study.
Al Sheddi MA
Saudi Med J 2012 Mar;33(3):304-8. PMID: 22426912

Diagnosis

Dentigerous cyst: enucleation or marsupialization? (a case report).
Rajae EG, Karima EH
Pan Afr Med J 2021;40:149. Epub 2021 Nov 10 doi: 10.11604/pamj.2021.40.149.28645. PMID: 34925684Free PMC Article
Dentigerous cyst in a young child: a case report.
McKinney SL, Lukes SM
Can J Dent Hyg 2021 Oct;55(3):177-181. Epub 2021 Oct 1 PMID: 34925518Free PMC Article
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Large Dentigerous Cyst Associated to Maxillary Canine.
Bonardi JP, Gomes-Ferreira PH, de Freitas Silva L, Momesso GA, de Oliveira D, Ferreira S, Pereira RD, Souza FÁ
J Craniofac Surg 2017 Jan;28(1):e96-e97. doi: 10.1097/SCS.0000000000003281. PMID: 27941544
Nasopalatine cyst.
BLAKE H, BLAKE FS
Oral Surg Oral Med Oral Pathol 1954 Oct;7(10):1062-5. doi: 10.1016/0030-4220(54)90214-5. PMID: 13203947

Therapy

Factors influencing an eruption of teeth associated with a dentigerous cyst: a systematic review and meta-analysis.
Nahajowski M, Hnitecka S, Antoszewska-Smith J, Rumin K, Dubowik M, Sarul M
BMC Oral Health 2021 Apr 7;21(1):180. doi: 10.1186/s12903-021-01542-y. PMID: 33827533Free PMC Article
p63 expression in randomized odontogenic cysts.
Seyedmajidi M, Shafaee S, Shafigh E, Bijani A, Hamidi H
Saudi Med J 2011 May;32(5):463-6. PMID: 21556465
Diplopia after inferior alveolar nerve block anesthesia: report of 2 cases and literature review.
Choi EH, Seo JY, Jung BY, Park W
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009 Jun;107(6):e21-4. doi: 10.1016/j.tripleo.2009.02.009. PMID: 19464638
Point of Care.
O'Keefe J
J Can Dent Assoc 2005 Oct;71(9):633-41. PMID: 16276641
Pathological sequelae of "neglected" impacted third molars.
Stanley HR, Alattar M, Collett WK, Stringfellow HR Jr, Spiegel EH
J Oral Pathol 1988 Mar;17(3):113-7. doi: 10.1111/j.1600-0714.1988.tb01896.x. PMID: 3135372

Prognosis

Odontogenic and Developmental Oral Lesions in Pediatric Patients.
Bilodeau EA, Hunter KD
Head Neck Pathol 2021 Mar;15(1):71-84. Epub 2021 Mar 15 doi: 10.1007/s12105-020-01284-3. PMID: 33723756Free PMC Article
Relevance of periodic evaluation of endodontically treated primary teeth.
Kamal El-Din Mohamed S, Abutayyem H, Abdelnabi S, Alkhabuli J
Libyan J Med 2019 Dec;14(1):1643208. doi: 10.1080/19932820.2019.1643208. PMID: 31339472Free PMC Article
Endoscopic enucleation of large jaw cysts: Promising outcomes.
Abdelwahab M, Elfattah AMA, Khafagy YW, El-Degwi A
Auris Nasus Larynx 2018 Jun;45(3):578-584. Epub 2017 Sep 24 doi: 10.1016/j.anl.2017.08.008. PMID: 28951046
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Benign cysts and tumors of the paranasal sinuses.
Pierse JE, Stern A
Oral Maxillofac Surg Clin North Am 2012 May;24(2):249-64, ix. Epub 2012 Feb 14 doi: 10.1016/j.coms.2012.01.007. PMID: 22341510

Clinical prediction guides

Large Dentigerous Cyst Associated to Maxillary Canine.
Bonardi JP, Gomes-Ferreira PH, de Freitas Silva L, Momesso GA, de Oliveira D, Ferreira S, Pereira RD, Souza FÁ
J Craniofac Surg 2017 Jan;28(1):e96-e97. doi: 10.1097/SCS.0000000000003281. PMID: 27941544
Odontogenic lesions in pediatric patients.
Fang QG, Shi S, Sun CF
J Craniofac Surg 2014 May;25(3):e248-51. doi: 10.1097/SCS.0000000000000548. PMID: 24785745
An unfamiliar presentation of a lateral periodontal cyst.
Byatnal AR, Parvathidevi MK, Rukmangada T, Koppal S
BMJ Case Rep 2013 Oct 9;2013 doi: 10.1136/bcr-2013-200852. PMID: 24108771Free PMC Article
PTCH gene altered in dentigerous cysts.
Pavelić B, Levanat S, Crnić I, Kobler P, Anić I, Manojlović S, Sutalo J
J Oral Pathol Med 2001 Oct;30(9):569-76. doi: 10.1034/j.1600-0714.2001.300911.x. PMID: 11555162
Unicystic ameloblastoma: a prognostically distinct entity.
Robinson L, Martinez MG
Cancer 1977 Nov;40(5):2278-85. doi: 10.1002/1097-0142(197711)40:5<2278::aid-cncr2820400539>3.0.co;2-l. PMID: 922668

Recent systematic reviews

Pediatric Odontogenic and Maxillofacial Bone Pathology: A Global Analysis.
Garg RK, O'Connor MK, Sterling DA, Jacob L, Hammoudeh JA, Andrews BT
J Craniofac Surg 2022 May 1;33(3):870-874. Epub 2021 Sep 23 doi: 10.1097/SCS.0000000000008201. PMID: 34560739
Cyst or Tumor? A systematic review and meta-analysis on the expression of p53 marker in Odontogenic Keratocysts.
Slusarenko da Silva Y, Stoelinga PJW, Grillo R, da Graça Naclério-Homem M
J Craniomaxillofac Surg 2021 Dec;49(12):1101-1106. Epub 2021 Sep 28 doi: 10.1016/j.jcms.2021.09.015. PMID: 34620539
Factors influencing an eruption of teeth associated with a dentigerous cyst: a systematic review and meta-analysis.
Nahajowski M, Hnitecka S, Antoszewska-Smith J, Rumin K, Dubowik M, Sarul M
BMC Oral Health 2021 Apr 7;21(1):180. doi: 10.1186/s12903-021-01542-y. PMID: 33827533Free PMC Article
Management of odontogenic cysts by endonasal endoscopic techniques: A systematic review and case series.
Marino MJ, Luong A, Yao WC, Citardi MJ
Am J Rhinol Allergy 2018 Jan 1;32(1):40-45. doi: 10.2500/ajra.2018.32.4492. PMID: 29336289
Frequency of odontogenic cysts and tumors: a systematic review.
Johnson NR, Gannon OM, Savage NW, Batstone MD
J Investig Clin Dent 2014 Feb;5(1):9-14. Epub 2013 Jun 14 doi: 10.1111/jicd.12044. PMID: 23766099

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