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Squamous cell intraepithelial neoplasia

MedGen UID:
83092
•Concept ID:
C0333873
•
Neoplastic Process
Synonyms: Intraepithelial Lesion, Squamous; Lesions, Squamous Intraepithelial; Squamous Intraepithelial Lesion; Squamous Intraepithelial Lesions
SNOMED CT: Squamous intraepithelial lesion (24253004); SIL - squamous intraepithelial lesion (24253004)
 
Monarch Initiative: MONDO:0024475

Definition

A precancerous neoplastic intraepithelial process involving the squamous epithelium. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSquamous cell intraepithelial neoplasia

Professional guidelines

PubMed

Treatment of ocular surface squamous cell intraepithelial neoplasia with and without mitomycin C.
Birkholz ES, Goins KM, Sutphin JE, Kitzmann AS, Wagoner MD
Cornea 2011 Jan;30(1):37-41. doi: 10.1097/ICO.0b013e3181dee560. PMID: 20861726

Recent clinical studies

Etiology

Surface maturation scoring for oesophageal squamous intraepithelial neoplasia: a novel diagnostic approach inspired by first endomicroscopic 3-dimensional reconstruction.
Li M, Zuo XL, Yu T, Gu XM, Zhou CJ, Li Z, Liu H, Ji R, Dong YY, Li CQ, Li YQ
Gut 2013 Nov;62(11):1547-55. Epub 2012 Aug 30 doi: 10.1136/gutjnl-2011-301946. PMID: 22936670
Treatment of ocular surface squamous cell intraepithelial neoplasia with and without mitomycin C.
Birkholz ES, Goins KM, Sutphin JE, Kitzmann AS, Wagoner MD
Cornea 2011 Jan;30(1):37-41. doi: 10.1097/ICO.0b013e3181dee560. PMID: 20861726
Pagetoid squamous cell carcinoma in situ of the vulva: comparison with extramammary paget disease and nonpagetoid squamous cell neoplasia.
Armes JE, Lourie R, Bowlay G, Tabrizi S
Int J Gynecol Pathol 2008 Jan;27(1):118-24. doi: 10.1097/pgp.0b013e318142acf0. PMID: 18156986
Monitoring the course of cervical carcinoma with the squamous cell carcinoma serum radioimmunoassay.
Holloway RW, To A, Moradi M, Boots L, Watson N, Shingleton HM
Obstet Gynecol 1989 Dec;74(6):944-9. PMID: 2586961

Diagnosis

Surface maturation scoring for oesophageal squamous intraepithelial neoplasia: a novel diagnostic approach inspired by first endomicroscopic 3-dimensional reconstruction.
Li M, Zuo XL, Yu T, Gu XM, Zhou CJ, Li Z, Liu H, Ji R, Dong YY, Li CQ, Li YQ
Gut 2013 Nov;62(11):1547-55. Epub 2012 Aug 30 doi: 10.1136/gutjnl-2011-301946. PMID: 22936670
Pagetoid squamous cell carcinoma in situ of the vulva: comparison with extramammary paget disease and nonpagetoid squamous cell neoplasia.
Armes JE, Lourie R, Bowlay G, Tabrizi S
Int J Gynecol Pathol 2008 Jan;27(1):118-24. doi: 10.1097/pgp.0b013e318142acf0. PMID: 18156986
Monitoring the course of cervical carcinoma with the squamous cell carcinoma serum radioimmunoassay.
Holloway RW, To A, Moradi M, Boots L, Watson N, Shingleton HM
Obstet Gynecol 1989 Dec;74(6):944-9. PMID: 2586961

Therapy

Surface maturation scoring for oesophageal squamous intraepithelial neoplasia: a novel diagnostic approach inspired by first endomicroscopic 3-dimensional reconstruction.
Li M, Zuo XL, Yu T, Gu XM, Zhou CJ, Li Z, Liu H, Ji R, Dong YY, Li CQ, Li YQ
Gut 2013 Nov;62(11):1547-55. Epub 2012 Aug 30 doi: 10.1136/gutjnl-2011-301946. PMID: 22936670
Treatment of ocular surface squamous cell intraepithelial neoplasia with and without mitomycin C.
Birkholz ES, Goins KM, Sutphin JE, Kitzmann AS, Wagoner MD
Cornea 2011 Jan;30(1):37-41. doi: 10.1097/ICO.0b013e3181dee560. PMID: 20861726

Prognosis

Treatment of ocular surface squamous cell intraepithelial neoplasia with and without mitomycin C.
Birkholz ES, Goins KM, Sutphin JE, Kitzmann AS, Wagoner MD
Cornea 2011 Jan;30(1):37-41. doi: 10.1097/ICO.0b013e3181dee560. PMID: 20861726
Monitoring the course of cervical carcinoma with the squamous cell carcinoma serum radioimmunoassay.
Holloway RW, To A, Moradi M, Boots L, Watson N, Shingleton HM
Obstet Gynecol 1989 Dec;74(6):944-9. PMID: 2586961

Clinical prediction guides

Surface maturation scoring for oesophageal squamous intraepithelial neoplasia: a novel diagnostic approach inspired by first endomicroscopic 3-dimensional reconstruction.
Li M, Zuo XL, Yu T, Gu XM, Zhou CJ, Li Z, Liu H, Ji R, Dong YY, Li CQ, Li YQ
Gut 2013 Nov;62(11):1547-55. Epub 2012 Aug 30 doi: 10.1136/gutjnl-2011-301946. PMID: 22936670
Monitoring the course of cervical carcinoma with the squamous cell carcinoma serum radioimmunoassay.
Holloway RW, To A, Moradi M, Boots L, Watson N, Shingleton HM
Obstet Gynecol 1989 Dec;74(6):944-9. PMID: 2586961

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