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Malignant Ovarian Thecoma

MedGen UID:
83139
Concept ID:
C0334398
Neoplastic Process
Synonyms: Malignant Ovarian Thecal Cell Neoplasm; Malignant Ovarian Thecal Cell Tumor; Malignant Thecal Cell Neoplasm of Ovary; Malignant Thecal Cell Neoplasm of the Ovary; Malignant Thecal Cell Tumor of Ovary; Malignant Thecal Cell Tumor of the Ovary; Malignant thecoma; Malignant Thecoma of Ovary; Malignant Thecoma of the Ovary; Thecoma, malignant
SNOMED CT: Malignant thecoma (57622002); Thecoma, malignant (57622002)

Definition

A thecoma of the ovary which may metastasize to another anatomic site. It is usually characterized by nuclear atypia and mitotic activity. Malignant thecomas are rare. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Roth LM
Expert Rev Anticancer Ther 2021 Mar;21(3):239-240. Epub 2020 Dec 8 doi: 10.1080/14737140.2021.1853530. PMID: 33290110
Irving JA, McCluggage WG
Adv Anat Pathol 2007 Sep;14(5):305-19. doi: 10.1097/PAP.0b013e3180ca8a5b. PMID: 17717430
Bridgewater JA, Rustin GJ
Oncology 1999;57(2):89-98. doi: 10.1159/000012014. PMID: 10461054

Recent clinical studies

Etiology

Pat JJ, Rothnie KK, Kolomainen D, Sundaresan M, Zhang J, Liyanage SH
Br J Radiol 2022 Aug 1;95(1136):20210790. Epub 2022 Jul 12 doi: 10.1259/bjr.20210790. PMID: 35451310Free PMC Article
Javadi S, Ganeshan DM, Jensen CT, Iyer RB, Bhosale PR
Abdom Radiol (NY) 2021 Apr;46(4):1519-1529. Epub 2021 Mar 16 doi: 10.1007/s00261-021-02998-w. PMID: 33725145
Young RH
Pathology 2018 Jan;50(1):5-15. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.007. PMID: 29132723
Chen H, Liu Y, Shen LF, Jiang MJ, Yang ZF, Fang GP
J Ovarian Res 2016 Nov 22;9(1):81. doi: 10.1186/s13048-016-0291-2. PMID: 27876070Free PMC Article
Roth LM, Czernobilsky B
Am J Surg Pathol 2011 Mar;35(3):e15-33. doi: 10.1097/PAS.0b013e31820acb89. PMID: 21317704

Diagnosis

Costeira FS, Félix A, Cunha TM
Br J Radiol 2022 Feb 1;95(1130):20210687. Epub 2021 Dec 20 doi: 10.1259/bjr.20210687. PMID: 34928171Free PMC Article
Schoolmeester JK, Erickson LA
Mayo Clin Proc 2019 Aug;94(8):1652-1653. doi: 10.1016/j.mayocp.2019.04.019. PMID: 31378246
Hanley KZ, Mosunjac MB
Surg Pathol Clin 2019 Jun;12(2):587-620. doi: 10.1016/j.path.2019.02.005. PMID: 31097116
Haghayeghi K, Hansen K, Quddus MR
Int J Surg Pathol 2019 Sep;27(6):654-655. Epub 2018 Dec 6 doi: 10.1177/1066896918817372. PMID: 30520326
Young RH
Pathology 2018 Jan;50(1):5-15. Epub 2017 Nov 11 doi: 10.1016/j.pathol.2017.09.007. PMID: 29132723

Therapy

Hendricks M, Cois A, Geel J, van Heerden J, Naidu G, du Plessis J, Bassingthwaighte M, van Zyl A, Uys R, Bϋchner A, Rowe B, Omar F, Mahlachana N, Thomas K, Vermeulen J, Davidson A, Donald KA, Kruger M
J Pediatr Hematol Oncol 2021 Jul 1;43(5):e619-e624. doi: 10.1097/MPH.0000000000002076. PMID: 33560080
Mellembakken JR, Engh V, Tanbo T, Czernobilsky B, Edelstein E, Lunde O, Roth LM
Pathol Res Pract 2010 Nov 15;206(11):744-8. Epub 2010 Aug 8 doi: 10.1016/j.prp.2010.07.001. PMID: 20696537
Levavi H, Sabah G, Heifetz M, Feinmesser M
Eur J Gynaecol Oncol 2009;30(6):695-700. PMID: 20099509
Bridgewater JA, Rustin GJ
Oncology 1999;57(2):89-98. doi: 10.1159/000012014. PMID: 10461054
Press MF, Scully RE
Gynecol Oncol 1985 Jun;21(2):135-54. doi: 10.1016/0090-8258(85)90246-x. PMID: 2985476

Prognosis

Jiang MJ, Le Q, Yang BW, Yuan F, Chen H
J Ovarian Res 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0. PMID: 33865445Free PMC Article
Javadi S, Ganeshan DM, Jensen CT, Iyer RB, Bhosale PR
Abdom Radiol (NY) 2021 Apr;46(4):1519-1529. Epub 2021 Mar 16 doi: 10.1007/s00261-021-02998-w. PMID: 33725145
Schoolmeester JK, Erickson LA
Mayo Clin Proc 2019 Aug;94(8):1652-1653. doi: 10.1016/j.mayocp.2019.04.019. PMID: 31378246
Hanley KZ, Mosunjac MB
Surg Pathol Clin 2019 Jun;12(2):587-620. doi: 10.1016/j.path.2019.02.005. PMID: 31097116
Baser E, Erkilinc S, Esin S, Togrul C, Biberoglu E, Karaca MZ, Gungor T, Danisman N
Int J Gynaecol Obstet 2013 Nov;123(2):124-6. Epub 2013 Aug 14 doi: 10.1016/j.ijgo.2013.06.015. PMID: 24008309

Clinical prediction guides

Brillantino C, Errico ME, Minelli R, Esposito F, Pirisi P, Gaglione G, Grella MG, Ferrara D, Zeccolini M, Rossi E
Ann Ital Chir 2022 Jul 25;11 PMID: 36606361
Jiang MJ, Le Q, Yang BW, Yuan F, Chen H
J Ovarian Res 2021 Apr 17;14(1):53. doi: 10.1186/s13048-021-00805-0. PMID: 33865445Free PMC Article
Young RH
Arch Pathol Lab Med 2018 Dec;142(12):1459-1484. doi: 10.5858/arpa.2018-0291-RA. PMID: 30500284
Blake EA, Carter CM, Kashani BN, Kodama M, Mabuchi S, Yoshino K, Matsuo K
Eur J Obstet Gynecol Reprod Biol 2014 Apr;175:1-7. Epub 2013 Dec 25 doi: 10.1016/j.ejogrb.2013.12.025. PMID: 24439718
Lee S, Mao L, Wang Y, D'Silva M, Yoo CH, Wolf P, Chung WS, Takahashi E, Chung DY, Gittes RF
Microsurgery 1995;16(4):191-8. doi: 10.1002/micr.1920160406. PMID: 7674907

Recent systematic reviews

Muratori L, Trevisi E, Delcuratolo MD, Sperone P, Di Maio M
Expert Rev Anticancer Ther 2021 Jan;21(1):23-32. Epub 2020 Oct 22 doi: 10.1080/14737140.2021.1837629. PMID: 33053314
Blake EA, Carter CM, Kashani BN, Kodama M, Mabuchi S, Yoshino K, Matsuo K
Eur J Obstet Gynecol Reprod Biol 2014 Apr;175:1-7. Epub 2013 Dec 25 doi: 10.1016/j.ejogrb.2013.12.025. PMID: 24439718

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