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Benign soft tissue neoplasm

MedGen UID:
83151
•Concept ID:
C0334450
•
Neoplastic Process
Synonyms: Benign neoplasm of soft tissue; Benign Neoplasm of Soft Tissue; benign neoplasm of soft tissue; Benign neoplasm of soft tissues; Benign Neoplasm of the Soft Tissue; benign neoplasm of the soft tissue; Benign Soft Tissue Neoplasm; benign soft tissue neoplasm; Benign soft tissue tumor; Benign Soft Tissue Tumor; benign soft tissue tumor; benign soft tissue tumour; Benign tumor of soft tissue; Benign Tumor of Soft Tissue; benign tumor of soft tissue; Benign Tumor of the Soft Tissue; benign tumor of the soft tissue; benign tumour of soft tissue; benign tumour of the soft tissue; soft tissue neoplasm, benign; Soft tissue tumor, benign
SNOMED CT: Benign neoplasm of soft tissue (92069005); Benign soft tissue tumor (47623001); Benign neoplasm of soft tissues (92069005); Benign tumor of soft tissue (92069005); Soft tissue tumor, benign (47623001)
 
Monarch Initiative: MONDO:0044335

Definition

A neoplasm that arises from soft tissue and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign soft tissue neoplasm

Professional guidelines

PubMed

DIFFERENTIAL DIAGNOSIS OF SOFT TISSUE TUMORS.
Kapustianskyi D, Ivanytskyi I, Ivanytska T, Zhamardiy V, Donchenko V
Wiad Lek 2022;75(6):1596-1599. doi: 10.36740/WLek202206131. PMID: 35907241
Diagnosis and treatment of hand tumors.
Lazerges C, Degeorge B, Coulet B, Chammas M
Orthop Traumatol Surg Res 2022 Feb;108(1S):103153. Epub 2021 Nov 24 doi: 10.1016/j.otsr.2021.103153. PMID: 34838755
Prostate-specific Membrane Antigen PET: Clinical Utility in Prostate Cancer, Normal Patterns, Pearls, and Pitfalls.
Hofman MS, Hicks RJ, Maurer T, Eiber M
Radiographics 2018 Jan-Feb;38(1):200-217. doi: 10.1148/rg.2018170108. PMID: 29320333

Recent clinical studies

Etiology

Ultrasound-Guided Moving Shot Radiofrequency Ablation of Benign Soft Tissue Neoplasm.
Lin WC, Tai YF, Chen MH, Luo SD, Huang F, Chen WC, Chiang PL, Chen HL, Chen MH, Baek JH
Medicina (Kaunas) 2021 Aug 17;57(8) doi: 10.3390/medicina57080830. PMID: 34441036Free PMC Article
Intramuscular myxoma of the nasal vestibule.
Patsiaoura K, Anagnostou E, Benis N
Auris Nasus Larynx 2010 Feb;37(1):100-2. Epub 2009 May 2 doi: 10.1016/j.anl.2009.02.014. PMID: 19414229
Poroid hidradenoma. A case presentation.
Whitmore RM, Anderson CJ, Piper T
J Am Podiatr Med Assoc 1998 Oct;88(10):510-3. doi: 10.7547/87507315-88-10-510. PMID: 9791957
Soft tissue myofibroblastomas.
Herrera GA, Johnson WW, Lockard VG, Walker BL
Mod Pathol 1991 Sep;4(5):571-7. PMID: 1661895

Diagnosis

Tenosynovial chondromatosis of the wrist: A case report.
Chaves C, Bellemère P
Hand Surg Rehabil 2023 Jun;42(3):258-260. Epub 2023 Mar 17 doi: 10.1016/j.hansur.2023.02.005. PMID: 36933830
Unusual presentation of lipoma on the tongue.
Varma BR, Kumar KS, Verghese RS, Janardhanan M
BMJ Case Rep 2020 Apr 14;13(4) doi: 10.1136/bcr-2019-232485. PMID: 32295795Free PMC Article
Intramuscular myxoma: clinical and surgical observation notes on eleven cases.
Baltu Y, Arikan ŞM, Dölen UC, Uzun H, Alkan Bİ, Aydın O
Int Orthop 2017 Apr;41(4):837-843. Epub 2017 Jan 14 doi: 10.1007/s00264-016-3396-8. PMID: 28091767
Granular cell tumor in two oral anatomic sites.
Serpa MS, Costa-Neto H, de Oliveira PT, da Silveira ÉJ, de Medeiros AM
Eur Arch Otorhinolaryngol 2016 Oct;273(10):3439-41. Epub 2016 Mar 23 doi: 10.1007/s00405-016-4006-5. PMID: 27007285
Angiofibroma of soft tissue: clinicopathologic characterization of a distinctive benign fibrovascular neoplasm in a series of 37 cases.
Mariño-Enríquez A, Fletcher CD
Am J Surg Pathol 2012 Apr;36(4):500-8. doi: 10.1097/PAS.0b013e31823defbe. PMID: 22301504

Prognosis

Fibro-Osseous Pseudotumor Arising From Nail Bed of the Great Toe: A Rare Case of Recurrence.
Isaac AL, Siddiqui S, Vieweger D, Adams BW, Mirkin G, Hao X
J Foot Ankle Surg 2022 Jan-Feb;61(1):218-220. Epub 2021 Sep 20 doi: 10.1053/j.jfas.2021.09.008. PMID: 34686420
Granular cell tumor in a child: A rare case report.
Yilmaz ZS, Ersoz S
Indian J Pathol Microbiol 2020 Jul-Sep;63(3):478-480. doi: 10.4103/IJPM.IJPM_495_19. PMID: 32769346
Superficial Acral Fibromyxoma: Report of 13 Cases With New Immunohistochemical Findings.
Cullen D, Díaz Recuero JL, Cullen R, Rodríguez Peralto JL, Kutzner H, Requena L
Am J Dermatopathol 2017 Jan;39(1):14-22. doi: 10.1097/DAD.0000000000000639. PMID: 28045748
Spindle cell liposarcoma of the face: case report and literature review.
Agostini T, Catelani C, Acocella A, Franchi A, Bertolai R, Sacco R, Lazzeri D, Shokrollahi K
Br J Dermatol 2010 Sep;163(3):638-40. Epub 2010 May 8 doi: 10.1111/j.1365-2133.2010.09847.x. PMID: 20456346
GNAS1 mutations occur more commonly than previously thought in intramuscular myxoma.
Delaney D, Diss TC, Presneau N, Hing S, Berisha F, Idowu BD, O'Donnell P, Skinner JA, Tirabosco R, Flanagan AM
Mod Pathol 2009 May;22(5):718-24. Epub 2009 Mar 13 doi: 10.1038/modpathol.2009.32. PMID: 19287459

Clinical prediction guides

Granular Cell Tumor in Auditory Meatus: A Case Report.
Lili L, Fei H, Hui H, Liyong Q
Ear Nose Throat J 2024 Feb;103(2):87-89. Epub 2021 Aug 23 doi: 10.1177/01455613211038234. PMID: 34420421
Intramuscular myxoma: clinical and surgical observation notes on eleven cases.
Baltu Y, Arikan ŞM, Dölen UC, Uzun H, Alkan Bİ, Aydın O
Int Orthop 2017 Apr;41(4):837-843. Epub 2017 Jan 14 doi: 10.1007/s00264-016-3396-8. PMID: 28091767
Superficial Acral Fibromyxoma: Report of 13 Cases With New Immunohistochemical Findings.
Cullen D, Díaz Recuero JL, Cullen R, Rodríguez Peralto JL, Kutzner H, Requena L
Am J Dermatopathol 2017 Jan;39(1):14-22. doi: 10.1097/DAD.0000000000000639. PMID: 28045748
Granular cell tumor in two oral anatomic sites.
Serpa MS, Costa-Neto H, de Oliveira PT, da Silveira ÉJ, de Medeiros AM
Eur Arch Otorhinolaryngol 2016 Oct;273(10):3439-41. Epub 2016 Mar 23 doi: 10.1007/s00405-016-4006-5. PMID: 27007285
Angiofibroma of soft tissue: clinicopathologic characterization of a distinctive benign fibrovascular neoplasm in a series of 37 cases.
Mariño-Enríquez A, Fletcher CD
Am J Surg Pathol 2012 Apr;36(4):500-8. doi: 10.1097/PAS.0b013e31823defbe. PMID: 22301504

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