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Fetal Rhabdomyoma

MedGen UID:
83156
Concept ID:
C0334482
Neoplastic Process
Synonyms: Fetal rhabdomyoma; Foetal rhabdomyoma
SNOMED CT: Fetal rhabdomyoma (404049001); Foetal rhabdomyoma (40123003); Foetal rhabdomyoma (404049001); Fetal rhabdomyoma (40123003)

Definition

A rare benign mesenchymal neoplasm arising from skeletal muscle. It is characterized by the presence of immature spindle and polygonal cells within a scant myxoid stroma. It usually develops in the head and neck region of young children. [from NCI]

Professional guidelines

PubMed

Dagge A, Silva LA, Jorge S, Nogueira E, Rebelo M, Pinto L
Fetal Pediatr Pathol 2022 Oct;41(5):800-806. Epub 2021 Jul 19 doi: 10.1080/15513815.2021.1948646. PMID: 34281475
Zhen L, Yang YD, He Y, Pan M, Han J, Yang X, Xu LL, Li DZ
Eur J Obstet Gynecol Reprod Biol 2020 Jun;249:7-10. Epub 2020 Apr 10 doi: 10.1016/j.ejogrb.2020.03.051. PMID: 32320828
Hansen T, Katenkamp D
Virchows Arch 2005 Nov;447(5):849-54. Epub 2005 Aug 18 doi: 10.1007/s00428-005-0038-8. PMID: 16133368

Recent clinical studies

Etiology

Okmen F, Ekici H, Hortu I, Imamoglu M, Ucar B, Ergenoglu AM, Sagol S
J Matern Fetal Neonatal Med 2022 Sep;35(18):3489-3494. Epub 2020 Sep 20 doi: 10.1080/14767058.2020.1822316. PMID: 32954877
Zhen L, Yang YD, He Y, Pan M, Han J, Yang X, Xu LL, Li DZ
Eur J Obstet Gynecol Reprod Biol 2020 Jun;249:7-10. Epub 2020 Apr 10 doi: 10.1016/j.ejogrb.2020.03.051. PMID: 32320828
Valdez TA, Desai U, Volk MS
Int J Pediatr Otorhinolaryngol 2006 Jun;70(6):1115-8. Epub 2006 Jan 6 doi: 10.1016/j.ijporl.2005.10.024. PMID: 16406074
Bader RS, Chitayat D, Kelly E, Ryan G, Smallhorn JF, Toi A, Hornberger LK
J Pediatr 2003 Nov;143(5):620-4. doi: 10.1067/S0022-3476(03)00494-3. PMID: 14615733
Jacques SM, Lawrence WD, Malviya VK
Gynecol Oncol 1993 Feb;48(2):272-6. doi: 10.1006/gyno.1993.1047. PMID: 8428702

Diagnosis

Wang Z, Ma B, Nie F
Int J Cardiovasc Imaging 2023 Dec;39(12):2483-2485. Epub 2023 Sep 30 doi: 10.1007/s10554-023-02954-3. PMID: 37776385
Zhen L, Yang YD, He Y, Pan M, Han J, Yang X, Xu LL, Li DZ
Eur J Obstet Gynecol Reprod Biol 2020 Jun;249:7-10. Epub 2020 Apr 10 doi: 10.1016/j.ejogrb.2020.03.051. PMID: 32320828
González-Pérez L, Alvarez-Argüelles H, Ramos Gutiérrez VJ, Hernández SG, Plata Bello AC, Concepción Masip T, Salido Ruiz E
Urol Int 2018;101(2):240-244. Epub 2017 Dec 8 doi: 10.1159/000485256. PMID: 29224022
Hansen T, Katenkamp D
Virchows Arch 2005 Nov;447(5):849-54. Epub 2005 Aug 18 doi: 10.1007/s00428-005-0038-8. PMID: 16133368
Bader RS, Chitayat D, Kelly E, Ryan G, Smallhorn JF, Toi A, Hornberger LK
J Pediatr 2003 Nov;143(5):620-4. doi: 10.1067/S0022-3476(03)00494-3. PMID: 14615733

Therapy

Dagge A, Silva LA, Jorge S, Nogueira E, Rebelo M, Pinto L
Fetal Pediatr Pathol 2022 Oct;41(5):800-806. Epub 2021 Jul 19 doi: 10.1080/15513815.2021.1948646. PMID: 34281475
Leboulanger N, Picard A, Roger G, Garabedian EN
Eur Ann Otorhinolaryngol Head Neck Dis 2010 Mar;127(1):30-2. Epub 2010 Mar 25 doi: 10.1016/j.anorl.2010.02.008. PMID: 20822754
Wertheim RA, Krebs HB, Frable WJ
Diagn Gynecol Obstet 1982 Spring;4(1):57-62. PMID: 7075448
Dehner LP, Enzinger FM, Font RL
Cancer 1972 Jul;30(1):160-6. doi: 10.1002/1097-0142(197207)30:1<160::aid-cncr2820300123>3.0.co;2-w. PMID: 5040740

Prognosis

Wang Z, Ma B, Nie F
Int J Cardiovasc Imaging 2023 Dec;39(12):2483-2485. Epub 2023 Sep 30 doi: 10.1007/s10554-023-02954-3. PMID: 37776385
Dagge A, Silva LA, Jorge S, Nogueira E, Rebelo M, Pinto L
Fetal Pediatr Pathol 2022 Oct;41(5):800-806. Epub 2021 Jul 19 doi: 10.1080/15513815.2021.1948646. PMID: 34281475
Zhen L, Yang YD, He Y, Pan M, Han J, Yang X, Xu LL, Li DZ
Eur J Obstet Gynecol Reprod Biol 2020 Jun;249:7-10. Epub 2020 Apr 10 doi: 10.1016/j.ejogrb.2020.03.051. PMID: 32320828
Valdez TA, Desai U, Volk MS
Int J Pediatr Otorhinolaryngol 2006 Jun;70(6):1115-8. Epub 2006 Jan 6 doi: 10.1016/j.ijporl.2005.10.024. PMID: 16406074
Bader RS, Chitayat D, Kelly E, Ryan G, Smallhorn JF, Toi A, Hornberger LK
J Pediatr 2003 Nov;143(5):620-4. doi: 10.1067/S0022-3476(03)00494-3. PMID: 14615733

Clinical prediction guides

Wang Z, Ma B, Nie F
Int J Cardiovasc Imaging 2023 Dec;39(12):2483-2485. Epub 2023 Sep 30 doi: 10.1007/s10554-023-02954-3. PMID: 37776385
Okmen F, Ekici H, Hortu I, Imamoglu M, Ucar B, Ergenoglu AM, Sagol S
J Matern Fetal Neonatal Med 2022 Sep;35(18):3489-3494. Epub 2020 Sep 20 doi: 10.1080/14767058.2020.1822316. PMID: 32954877
Hansen T, Katenkamp D
Virchows Arch 2005 Nov;447(5):849-54. Epub 2005 Aug 18 doi: 10.1007/s00428-005-0038-8. PMID: 16133368
Bader RS, Chitayat D, Kelly E, Ryan G, Smallhorn JF, Toi A, Hornberger LK
J Pediatr 2003 Nov;143(5):620-4. doi: 10.1067/S0022-3476(03)00494-3. PMID: 14615733
Gorlin RJ
Medicine (Baltimore) 1987 Mar;66(2):98-113. doi: 10.1097/00005792-198703000-00002. PMID: 3547011

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