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Primary plasmacytoma of the bone

MedGen UID:
832012
•Concept ID:
CN197327
•
Neoplastic Process
Synonym: primary plasmacytoma of the bone
 
Monarch Initiative: MONDO:0015042
Orphanet: ORPHA100021

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary plasmacytoma of the bone

Professional guidelines

PubMed

Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria.
Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, Hungria VTM, Sandes AF, Rizzatti EG, Nico MAC
Radiographics 2019 Jul-Aug;39(4):1077-1097. doi: 10.1148/rg.2019180096. PMID: 31283452
Differential diagnosis of primary malignant bone tumors in the spine and sacrum. The radiological and clinical spectrum: minireview.
Knoeller SM, Uhl M, Gahr N, Adler CP, Herget GW
Neoplasma 2008;55(1):16-22. PMID: 18190235
Surgical management of malignant tumors of the adult bony spine.
Cahill DW
South Med J 1996 Jul;89(7):653-65. doi: 10.1097/00007611-199607000-00002. PMID: 8685749

Recent clinical studies

Etiology

Plasma cell neoplasms and related entities-evolution in diagnosis and classification.
Fend F, Dogan A, Cook JR
Virchows Arch 2023 Jan;482(1):163-177. Epub 2022 Nov 21 doi: 10.1007/s00428-022-03431-3. PMID: 36414803Free PMC Article
Clinical outcomes of tumors and tumor-like lesions located in the clavicle.
Korkmaz İ, Ulucaköy C, Ayhan B, Büyükdemirci E, Semis HS, Atalay İB, Güngör BŞ
Jt Dis Relat Surg 2022;33(2):449-454. Epub 2022 Jul 6 doi: 10.52312/jdrs.2022.669. PMID: 35852207Free PMC Article
Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study.
Cavo M, Gay F, Beksac M, Pantani L, Petrucci MT, Dimopoulos MA, Dozza L, van der Holt B, Zweegman S, Oliva S, van der Velden VHJ, Zamagni E, Palumbo GA, Patriarca F, Montefusco V, Galli M, Maisnar V, Gamberi B, Hansson M, Belotti A, Pour L, Ypma P, Grasso M, Croockewit A, Ballanti S, Offidani M, Vincelli ID, Zambello R, Liberati AM, Andersen NF, Broijl A, Troia R, Pascarella A, Benevolo G, Levin MD, Bos G, Ludwig H, Aquino S, Morelli AM, Wu KL, Boersma R, Hajek R, Durian M, von dem Borne PA, Caravita di Toritto T, Zander T, Driessen C, Specchia G, Waage A, Gimsing P, Mellqvist UH, van Marwijk Kooy M, Minnema M, Mandigers C, Cafro AM, Palmas A, Carvalho S, Spencer A, Boccadoro M, Sonneveld P
Lancet Haematol 2020 Jun;7(6):e456-e468. Epub 2020 Apr 30 doi: 10.1016/S2352-3026(20)30099-5. PMID: 32359506
Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria.
Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, Hungria VTM, Sandes AF, Rizzatti EG, Nico MAC
Radiographics 2019 Jul-Aug;39(4):1077-1097. doi: 10.1148/rg.2019180096. PMID: 31283452
Primary malignant clavicular tumours: a clinicopathological analysis of six cases and evaluation of surgical management.
Rossi B, Fabbriciani C, Chalidis BE, Visci F, Maccauro G
Arch Orthop Trauma Surg 2011 Jul;131(7):935-9. Epub 2010 Dec 25 doi: 10.1007/s00402-010-1237-6. PMID: 21188396

Diagnosis

Plasma cell neoplasms and related entities-evolution in diagnosis and classification.
Fend F, Dogan A, Cook JR
Virchows Arch 2023 Jan;482(1):163-177. Epub 2022 Nov 21 doi: 10.1007/s00428-022-03431-3. PMID: 36414803Free PMC Article
Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study.
Cavo M, Gay F, Beksac M, Pantani L, Petrucci MT, Dimopoulos MA, Dozza L, van der Holt B, Zweegman S, Oliva S, van der Velden VHJ, Zamagni E, Palumbo GA, Patriarca F, Montefusco V, Galli M, Maisnar V, Gamberi B, Hansson M, Belotti A, Pour L, Ypma P, Grasso M, Croockewit A, Ballanti S, Offidani M, Vincelli ID, Zambello R, Liberati AM, Andersen NF, Broijl A, Troia R, Pascarella A, Benevolo G, Levin MD, Bos G, Ludwig H, Aquino S, Morelli AM, Wu KL, Boersma R, Hajek R, Durian M, von dem Borne PA, Caravita di Toritto T, Zander T, Driessen C, Specchia G, Waage A, Gimsing P, Mellqvist UH, van Marwijk Kooy M, Minnema M, Mandigers C, Cafro AM, Palmas A, Carvalho S, Spencer A, Boccadoro M, Sonneveld P
Lancet Haematol 2020 Jun;7(6):e456-e468. Epub 2020 Apr 30 doi: 10.1016/S2352-3026(20)30099-5. PMID: 32359506
Bone Pathology for Hematopathologists.
Peker D, Wei S, Siegal GP
Surg Pathol Clin 2019 Sep;12(3):831-847. Epub 2019 May 22 doi: 10.1016/j.path.2019.03.007. PMID: 31352990
Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria.
Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, Hungria VTM, Sandes AF, Rizzatti EG, Nico MAC
Radiographics 2019 Jul-Aug;39(4):1077-1097. doi: 10.1148/rg.2019180096. PMID: 31283452
Neuroimaging of spine tumors.
Pinter NK, Pfiffner TJ, Mechtler LL
Handb Clin Neurol 2016;136:689-706. doi: 10.1016/B978-0-444-53486-6.00033-8. PMID: 27430436

Therapy

Kyphoplasty in the Early Oncologic Diagnosis and Treatment of Vertebral Fractures: A Clinical Study.
Akyuva Y, Baysoy B, Savrunlu EC, Sezen GB, Boyali O, Can H, Civelek E, Kabatas S
Turk Neurosurg 2020;30(4):588-594. doi: 10.5137/1019-5149.JTN.29550-20.2. PMID: 32530483
Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study.
Cavo M, Gay F, Beksac M, Pantani L, Petrucci MT, Dimopoulos MA, Dozza L, van der Holt B, Zweegman S, Oliva S, van der Velden VHJ, Zamagni E, Palumbo GA, Patriarca F, Montefusco V, Galli M, Maisnar V, Gamberi B, Hansson M, Belotti A, Pour L, Ypma P, Grasso M, Croockewit A, Ballanti S, Offidani M, Vincelli ID, Zambello R, Liberati AM, Andersen NF, Broijl A, Troia R, Pascarella A, Benevolo G, Levin MD, Bos G, Ludwig H, Aquino S, Morelli AM, Wu KL, Boersma R, Hajek R, Durian M, von dem Borne PA, Caravita di Toritto T, Zander T, Driessen C, Specchia G, Waage A, Gimsing P, Mellqvist UH, van Marwijk Kooy M, Minnema M, Mandigers C, Cafro AM, Palmas A, Carvalho S, Spencer A, Boccadoro M, Sonneveld P
Lancet Haematol 2020 Jun;7(6):e456-e468. Epub 2020 Apr 30 doi: 10.1016/S2352-3026(20)30099-5. PMID: 32359506
Primary Plasmacytoma in the Cerebellum: A Case Report and Literature Review.
Yanagihara W, Beppu T, Ogasawara Y, Ito S, Sato Y, Sugai T, Ogasawara K
World Neurosurg 2020 Feb;134:10-13. Epub 2019 Oct 16 doi: 10.1016/j.wneu.2019.10.036. PMID: 31629133
Primary extramedullary plasmacytoma with diffuse lymph node involvement: a case report and review of the literature.
Naymagon L, Abdul-Hay M
J Med Case Rep 2019 May 22;13(1):153. doi: 10.1186/s13256-019-2087-7. PMID: 31113466Free PMC Article
Testicular plasmacytoma misdiagnosed as orchitis.
Schiavo C, Mann SA, Mer J, Suvannasankha A
BMJ Case Rep 2018 Jun 4;2018 doi: 10.1136/bcr-2017-222046. PMID: 29866662Free PMC Article

Prognosis

Plasma cell neoplasms and related entities-evolution in diagnosis and classification.
Fend F, Dogan A, Cook JR
Virchows Arch 2023 Jan;482(1):163-177. Epub 2022 Nov 21 doi: 10.1007/s00428-022-03431-3. PMID: 36414803Free PMC Article
Bone Pathology for Hematopathologists.
Peker D, Wei S, Siegal GP
Surg Pathol Clin 2019 Sep;12(3):831-847. Epub 2019 May 22 doi: 10.1016/j.path.2019.03.007. PMID: 31352990
Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria.
Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, Hungria VTM, Sandes AF, Rizzatti EG, Nico MAC
Radiographics 2019 Jul-Aug;39(4):1077-1097. doi: 10.1148/rg.2019180096. PMID: 31283452
Hematopoietic Tumors Primarily Presenting in Bone.
Cleven AHG, Hogendoorn PCW
Surg Pathol Clin 2017 Sep;10(3):675-691. Epub 2017 Jun 27 doi: 10.1016/j.path.2017.04.011. PMID: 28797508
Neuroimaging of spine tumors.
Pinter NK, Pfiffner TJ, Mechtler LL
Handb Clin Neurol 2016;136:689-706. doi: 10.1016/B978-0-444-53486-6.00033-8. PMID: 27430436

Clinical prediction guides

Clinical outcomes of tumors and tumor-like lesions located in the clavicle.
Korkmaz İ, Ulucaköy C, Ayhan B, Büyükdemirci E, Semis HS, Atalay İB, Güngör BŞ
Jt Dis Relat Surg 2022;33(2):449-454. Epub 2022 Jul 6 doi: 10.52312/jdrs.2022.669. PMID: 35852207Free PMC Article
Prediction of Solitary Plasmacytoma of Bone in Elderly Patients: A Nomogram and a Risk Classification System for Overall Survival.
Zhang X, Yang J, Tian Z, Khabir Y, Wang D
Biomed Res Int 2022;2022:7387416. Epub 2022 Jun 1 doi: 10.1155/2022/7387416. PMID: 35692586Free PMC Article
Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria.
Ormond Filho AG, Carneiro BC, Pastore D, Silva IP, Yamashita SR, Consolo FD, Hungria VTM, Sandes AF, Rizzatti EG, Nico MAC
Radiographics 2019 Jul-Aug;39(4):1077-1097. doi: 10.1148/rg.2019180096. PMID: 31283452
Unusual extramedullary hematopoietic neoplasms in lymph nodes.
Dayton VD, Williams SJ, McKenna RW, Linden MA
Hum Pathol 2017 Apr;62:13-22. Epub 2016 Dec 23 doi: 10.1016/j.humpath.2016.12.014. PMID: 28025076
Primary malignant clavicular tumours: a clinicopathological analysis of six cases and evaluation of surgical management.
Rossi B, Fabbriciani C, Chalidis BE, Visci F, Maccauro G
Arch Orthop Trauma Surg 2011 Jul;131(7):935-9. Epub 2010 Dec 25 doi: 10.1007/s00402-010-1237-6. PMID: 21188396

Recent systematic reviews

Clinical features, radiological profiles, and surgical outcomes of primary intracranial solitary plasmacytomas: a report of 17 cases and a pooled analysis of individual patient data.
Ma XJ, Li D, Wang L, Hao SY, Zhang LW, Zhang JT, Wu Z
J Neurooncol 2019 Apr;142(2):263-272. Epub 2019 Jan 7 doi: 10.1007/s11060-019-03089-z. PMID: 30617445
Plasma Cell Myeloma - 20-Year Comparative Survival and Mortality of Three Plasma Cell Myeloma ICD-O-3 Oncologic Phenotypes by Age, Sex, Race, Stage, Cohort Entry Time-Period and Disease Duration: A Systematic Review of 111,041 Cases for Diagnosis Years 1973-2014: (SEER*Stat 8.3.4).
Milano AF
J Insur Med 2018;47(4):203-211. Epub 2019 Jan 22 doi: 10.17849/insm-47-04-1-9.1. PMID: 30668210
¹⁸F-FDG PET/CT: a review of diagnostic and prognostic features in multiple myeloma and related disorders.
Dammacco F, Rubini G, Ferrari C, Vacca A, Racanelli V
Clin Exp Med 2015 Feb;15(1):1-18. Epub 2014 Sep 14 doi: 10.1007/s10238-014-0308-3. PMID: 25218739

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