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Pituitary hemorrhage

MedGen UID:
83340
•Concept ID:
C0342406
•
Pathologic Function
Synonym: Pituitary Hemorrhage
SNOMED CT: Pituitary hemorrhage (237702003)

Definition

Bleeding within the pituitary gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary hemorrhage

Professional guidelines

PubMed

Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Clinical versus subclinical pituitary apoplexy: presentation, surgical management, and outcome in 21 patients.
Onesti ST, Wisniewski T, Post KD
Neurosurgery 1990 Jun;26(6):980-6. PMID: 2362675

Recent clinical studies

Etiology

Pituitary tumor apoplexy in adolescents.
Jankowski PP, Crawford JR, Khanna P, Malicki DM, Ciacci JD, Levy ML
World Neurosurg 2015 Apr;83(4):644-51. Epub 2014 Dec 18 doi: 10.1016/j.wneu.2014.12.026. PMID: 25527883
The prevalence and natural history of pituitary hemorrhage in prolactinoma.
Sarwar KN, Huda MS, Van de Velde V, Hopkins L, Luck S, Preston R, McGowan BM, Carroll PV, Powrie JK
J Clin Endocrinol Metab 2013 Jun;98(6):2362-7. Epub 2013 Apr 12 doi: 10.1210/jc.2013-1249. PMID: 23585661
Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Predisposing factors of pituitary hemorrhage.
Liu ZH, Tu PH, Pai PC, Chen NY, Lee ST, Chuang CC
Eur J Neurol 2012 May;19(5):733-8. Epub 2011 Dec 19 doi: 10.1111/j.1468-1331.2011.03619.x. PMID: 22182406
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318

Diagnosis

Pituitary tumor apoplexy in adolescents.
Jankowski PP, Crawford JR, Khanna P, Malicki DM, Ciacci JD, Levy ML
World Neurosurg 2015 Apr;83(4):644-51. Epub 2014 Dec 18 doi: 10.1016/j.wneu.2014.12.026. PMID: 25527883
Cavernous sinus invasion might be a risk factor for apoplexy.
Cinar N, Tekinel Y, Dagdelen S, Oruckaptan H, Soylemezoglu F, Erbas T
Pituitary 2013 Dec;16(4):483-9. doi: 10.1007/s11102-012-0444-2. PMID: 23179962
Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Predisposing factors of pituitary hemorrhage.
Liu ZH, Tu PH, Pai PC, Chen NY, Lee ST, Chuang CC
Eur J Neurol 2012 May;19(5):733-8. Epub 2011 Dec 19 doi: 10.1111/j.1468-1331.2011.03619.x. PMID: 22182406
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318

Therapy

Pituitary Apoplexy After Initial Leuprolide Injection.
Fabiano AJ, George S
World Neurosurg 2016 Nov;95:616.e7-616.e9. Epub 2016 Aug 29 doi: 10.1016/j.wneu.2016.08.091. PMID: 27586180
Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423
Predisposing factors of pituitary hemorrhage.
Liu ZH, Tu PH, Pai PC, Chen NY, Lee ST, Chuang CC
Eur J Neurol 2012 May;19(5):733-8. Epub 2011 Dec 19 doi: 10.1111/j.1468-1331.2011.03619.x. PMID: 22182406
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318
Resolution of Cushing's disease followed by secondary adrenal insufficiency after anticoagulant-associated pituitary hemorrhage: report of a case and review of the literature.
Taylor HC, McLean S, Monheim K
Endocr Pract 2003 Mar-Apr;9(2):147-51. doi: 10.4158/EP.9.2.147. PMID: 12917078

Prognosis

Is a stable or decreasing prolactin level in a patient with prolactinoma a surrogate marker for lack of tumor growth?
Alkabbani AG, Mon SY, Hatipoglu B, Kennedy L, Faiman C, Weil RJ, Hamrahian AH
Pituitary 2014 Apr;17(2):97-102. doi: 10.1007/s11102-013-0473-5. PMID: 23468127
Clinical features and surgical outcome of clinical and subclinical pituitary apoplexy.
Liu ZH, Chang CN, Pai PC, Wei KC, Jung SM, Chen NY, Chuang CC
J Clin Neurosci 2010 Jun;17(6):694-9. Epub 2010 Apr 18 doi: 10.1016/j.jocn.2009.11.012. PMID: 20400318
Factors affecting the development of hypothalamus and pituitary lesions in fatal closed head injury: a prospective study.
Chaturvedi D, Suri A, Kasliwal MK, Mahapatra AK, Mehta VS, Shridhar V, Garg A, Sarkar C, Dogra TD, Singh R
J Trauma 2010 Aug;69(2):290-3. doi: 10.1097/TA.0b013e3181b403b5. PMID: 20016386
Changing patterns of the adult growth hormone deficiency diagnosis documented in a decade-long global surveillance database.
Webb SM, Strasburger CJ, Mo D, Hartman ML, Melmed S, Jung H, Blum WF, Attanasio AF; HypoCCS International Advisory Board
J Clin Endocrinol Metab 2009 Feb;94(2):392-9. Epub 2008 Nov 11 doi: 10.1210/jc.2008-0713. PMID: 19001512
A retrospective analysis of pituitary apoplexy.
Bills DC, Meyer FB, Laws ER Jr, Davis DH, Ebersold MJ, Scheithauer BW, Ilstrup DM, Abboud CF
Neurosurgery 1993 Oct;33(4):602-8; discussion 608-9. doi: 10.1227/00006123-199310000-00007. PMID: 8232799

Clinical prediction guides

Pituitary Microadenoma Treated with Individualized Homeopathic Medicine: A Case Report.
Mathur M
Homeopathy 2020 Nov;109(4):243-247. Epub 2020 Aug 30 doi: 10.1055/s-0040-1713383. PMID: 32862414
Pituitary tumor apoplexy in adolescents.
Jankowski PP, Crawford JR, Khanna P, Malicki DM, Ciacci JD, Levy ML
World Neurosurg 2015 Apr;83(4):644-51. Epub 2014 Dec 18 doi: 10.1016/j.wneu.2014.12.026. PMID: 25527883
Is a stable or decreasing prolactin level in a patient with prolactinoma a surrogate marker for lack of tumor growth?
Alkabbani AG, Mon SY, Hatipoglu B, Kennedy L, Faiman C, Weil RJ, Hamrahian AH
Pituitary 2014 Apr;17(2):97-102. doi: 10.1007/s11102-013-0473-5. PMID: 23468127
Central nervous system-related symptoms and findings are common in acute Puumala hantavirus infection.
Hautala T, Mähönen SM, Sironen T, Hautala N, Pääkkö E, Karttunen A, Salmela PI, Ilonen J, Vainio O, Glumoff V, Rytky S, Plyusnin A, Vaheri A, Vapalahti O, Kauma H
Ann Med 2010 Jul;42(5):344-51. doi: 10.3109/07853890.2010.480979. PMID: 20545485
Factors affecting the development of hypothalamus and pituitary lesions in fatal closed head injury: a prospective study.
Chaturvedi D, Suri A, Kasliwal MK, Mahapatra AK, Mehta VS, Shridhar V, Garg A, Sarkar C, Dogra TD, Singh R
J Trauma 2010 Aug;69(2):290-3. doi: 10.1097/TA.0b013e3181b403b5. PMID: 20016386

Recent systematic reviews

Frequency of pituitary tumor apoplexy during treatment of prolactinomas with dopamine agonists: a systematic review.
Carija R, Vucina D
CNS Neurol Disord Drug Targets 2012 Dec;11(8):1012-4. doi: 10.2174/1871527311211080011. PMID: 23244423

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