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Benign epithelial skin neoplasm

MedGen UID:
83395
Concept ID:
C0345981
Neoplastic Process
Synonyms: Benign epithelial neoplasm of skin; Benign Epithelial Skin Neoplasm; benign epithelial skin neoplasm; Benign Epithelial Skin Tumor; benign epithelial skin tumor; benign epithelial skin tumour; Benign Skin Epithelium Neoplasm; benign skin epithelium neoplasm; Benign Skin Epithelium Tumor; benign skin epithelium tumor; benign skin epithelium tumour; Benign tumor of surface epithelium; epithelial skin neoplasm, benign
SNOMED CT: Benign epithelial neoplasm of skin (254658001); Benign tumor of surface epithelium (254658001)
 
Monarch Initiative: MONDO:0024666

Definition

An epithelial neoplasm that arises from the skin and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign epithelial skin neoplasm

Professional guidelines

PubMed

Alam MS, Pal SS, Krishnakumar S
Indian J Ophthalmol 2022 Jun;70(6):1975-1981. doi: 10.4103/ijo.IJO_2724_21. PMID: 35647965Free PMC Article
Płachta I, Kleibert M, Czarnecka AM, Spałek M, Szumera-Ciećkiewicz A, Rutkowski P
Int J Mol Sci 2021 Apr 30;22(9) doi: 10.3390/ijms22094759. PMID: 33946233Free PMC Article
Eversole LR
Eur J Cancer B Oral Oncol 1993 Jul;29B(3):173-9. doi: 10.1016/0964-1955(93)90019-b. PMID: 8298420

Recent clinical studies

Etiology

Pešut E, Đukić A, Lulić L, Skelin J, Šimić I, Milutin Gašperov N, Tomaić V, Sabol I, Grce M
Viruses 2021 Nov 6;13(11) doi: 10.3390/v13112234. PMID: 34835040Free PMC Article
Kaliterna V, Barisic Z
Front Biosci (Landmark Ed) 2018 Mar 1;23(9):1587-1611. doi: 10.2741/4662. PMID: 29293452
Egawa N, Doorbar J
Virus Res 2017 Mar 2;231:119-127. Epub 2016 Dec 28 doi: 10.1016/j.virusres.2016.12.017. PMID: 28040475
Pe'er J
Indian J Ophthalmol 2016 Mar;64(3):177-90. doi: 10.4103/0301-4738.181752. PMID: 27146927Free PMC Article
Okamura JM, Barr RJ
Adv Dermatol 1997;12:277-94; discussion 295. PMID: 8973744

Diagnosis

Porumb-Andrese E, Costea CF, Macovei G, Dumitrescu GF, Blaj LA, Prutianu I, Cucu AI
Rom J Morphol Embryol 2023 Oct-Dec;64(4):467-473. doi: 10.47162/RJME.64.4.02. PMID: 38184826Free PMC Article
Khalil J, Kurban M, Abbas O
Int J Dermatol 2021 Feb;60(2):159-165. Epub 2020 Sep 2 doi: 10.1111/ijd.15165. PMID: 32880923
Kaliterna V, Barisic Z
Front Biosci (Landmark Ed) 2018 Mar 1;23(9):1587-1611. doi: 10.2741/4662. PMID: 29293452
Welzel J, Schuh S
J Dtsch Dermatol Ges 2017 Oct;15(10):999-1016. doi: 10.1111/ddg.13347. PMID: 28976087
Ohsie SJ, Sarantopoulos GP, Cochran AJ, Binder SW
J Cutan Pathol 2008 May;35(5):433-44. doi: 10.1111/j.1600-0560.2007.00891.x. PMID: 18399807

Therapy

Todorova K, Mandinova A
Adv Drug Deliv Rev 2020 Jan 1;153:18-27. Epub 2020 Jun 8 doi: 10.1016/j.addr.2020.06.004. PMID: 32526451
Kaliterna V, Barisic Z
Front Biosci (Landmark Ed) 2018 Mar 1;23(9):1587-1611. doi: 10.2741/4662. PMID: 29293452
Darbre PD
Morphologie 2016 Jun;100(329):65-74. Epub 2016 Mar 17 doi: 10.1016/j.morpho.2016.02.001. PMID: 26997127
Curry JL, Torres-Cabala CA, Kim KB, Tetzlaff MT, Duvic M, Tsai KY, Hong DS, Prieto VG
Int J Dermatol 2014 Mar;53(3):376-84. Epub 2013 Jul 24 doi: 10.1111/ijd.12205. PMID: 23879247
Androphy EJ
Ciba Found Symp 1986;120:221-34. doi: 10.1002/9780470513309.ch15. PMID: 2424679

Prognosis

Gelmi MC, Houtzagers LE, Strub T, Krossa I, Jager MJ
Int J Mol Sci 2022 May 26;23(11) doi: 10.3390/ijms23116001. PMID: 35682684Free PMC Article
Prigge ES, von Knebel Doeberitz M, Reuschenbach M
Mutat Res Rev Mutat Res 2017 Apr-Jun;772:51-66. Epub 2016 Jun 22 doi: 10.1016/j.mrrev.2016.06.005. PMID: 28528690
Ansai SI
J Dermatol 2017 Mar;44(3):315-326. doi: 10.1111/1346-8138.13555. PMID: 28256768
Brenn T
Adv Anat Pathol 2014 Mar;21(2):108-30. doi: 10.1097/PAP.0000000000000009. PMID: 24508694
Ohsie SJ, Sarantopoulos GP, Cochran AJ, Binder SW
J Cutan Pathol 2008 May;35(5):433-44. doi: 10.1111/j.1600-0560.2007.00891.x. PMID: 18399807

Clinical prediction guides

Kar A, Pattnaik K, Kar T, Biswal P, Mishra C, Guru L
Indian J Pathol Microbiol 2020 Apr-Jun;63(2):177-187. doi: 10.4103/IJPM.IJPM_791_19. PMID: 32317512
Carter CS, Patel RM
Mod Pathol 2020 Jan;33(Suppl 1):66-82. Epub 2019 Nov 4 doi: 10.1038/s41379-019-0387-5. PMID: 31685962
Welzel J, Schuh S
J Dtsch Dermatol Ges 2017 Oct;15(10):999-1016. doi: 10.1111/ddg.13347. PMID: 28976087
Abbas O, Bhawan J
Int J Dermatol 2016 Feb;55(2):142-8. Epub 2015 Oct 13 doi: 10.1111/ijd.13040. PMID: 26460811
Brenn T
Adv Anat Pathol 2014 Mar;21(2):108-30. doi: 10.1097/PAP.0000000000000009. PMID: 24508694

Recent systematic reviews

Panda SK, Sahoo PK, Agarwala SK, Houghton TT, Sankar KV, Mohanty P
J Cancer Res Ther 2023 Jul-Sep;19(5):1098-1102. doi: 10.4103/jcrt.jcrt_720_21. PMID: 37787269
Todorova K, Mandinova A
Adv Drug Deliv Rev 2020 Jan 1;153:18-27. Epub 2020 Jun 8 doi: 10.1016/j.addr.2020.06.004. PMID: 32526451

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