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Anal margin neoplasm

MedGen UID:
834125
•Concept ID:
C2064234
•
Neoplastic Process
HPO: HP:0030440

Definition

A tumor of the anal margin. [from HPO]

Professional guidelines

PubMed

Rectal cancer lexicon 2023 revised and updated consensus statement from the Society of Abdominal Radiology Colorectal and Anal Cancer Disease-Focused Panel.
Lee S, Kassam Z, Baheti AD, Hope TA, Chang KJ, Korngold EK, Taggart MW, Horvat N
Abdom Radiol (NY) 2023 Sep;48(9):2792-2806. Epub 2023 May 5 doi: 10.1007/s00261-023-03893-2. PMID: 37145311Free PMC Article
ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.
Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
Neoadjuvant radiotherapy for rectal cancer management.
Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, Kerin M
World J Gastroenterol 2019 Sep 7;25(33):4850-4869. doi: 10.3748/wjg.v25.i33.4850. PMID: 31543678Free PMC Article

Recent clinical studies

Etiology

Comparison of Laparoscopic Versus Robot-Assisted Surgery for Rectal Cancers: The COLRAR Randomized Controlled Trial.
Park JS, Lee SM, Choi GS, Park SY, Kim HJ, Song SH, Min BS, Kim NK, Kim SH, Lee KY
Ann Surg 2023 Jul 1;278(1):31-38. Epub 2023 Jan 3 doi: 10.1097/SLA.0000000000005788. PMID: 36594748
Robotic versus laparoscopic surgery for middle and low rectal cancer (REAL): short-term outcomes of a multicentre randomised controlled trial.
Feng Q, Yuan W, Li T, Tang B, Jia B, Zhou Y, Zhang W, Zhao R, Zhang C, Cheng L, Zhang X, Liang F, He G, Wei Y, Xu J; REAL Study Group
Lancet Gastroenterol Hepatol 2022 Nov;7(11):991-1004. Epub 2022 Sep 8 doi: 10.1016/S2468-1253(22)00248-5. PMID: 36087608
The importance of MRI for rectal cancer evaluation.
Fernandes MC, Gollub MJ, Brown G
Surg Oncol 2022 Aug;43:101739. Epub 2022 Mar 18 doi: 10.1016/j.suronc.2022.101739. PMID: 35339339Free PMC Article
Neoadjuvant radiotherapy for rectal cancer management.
Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, Kerin M
World J Gastroenterol 2019 Sep 7;25(33):4850-4869. doi: 10.3748/wjg.v25.i33.4850. PMID: 31543678Free PMC Article
Australasian Gastrointestinal Trials Group (AGITG) contouring atlas and planning guidelines for intensity-modulated radiotherapy in anal cancer.
Ng M, Leong T, Chander S, Chu J, Kneebone A, Carroll S, Wiltshire K, Ngan S, Kachnic L
Int J Radiat Oncol Biol Phys 2012 Aug 1;83(5):1455-62. Epub 2012 Mar 6 doi: 10.1016/j.ijrobp.2011.12.058. PMID: 22401917

Diagnosis

Rectal cancer lexicon 2023 revised and updated consensus statement from the Society of Abdominal Radiology Colorectal and Anal Cancer Disease-Focused Panel.
Lee S, Kassam Z, Baheti AD, Hope TA, Chang KJ, Korngold EK, Taggart MW, Horvat N
Abdom Radiol (NY) 2023 Sep;48(9):2792-2806. Epub 2023 May 5 doi: 10.1007/s00261-023-03893-2. PMID: 37145311Free PMC Article
Comparison of Laparoscopic Versus Robot-Assisted Surgery for Rectal Cancers: The COLRAR Randomized Controlled Trial.
Park JS, Lee SM, Choi GS, Park SY, Kim HJ, Song SH, Min BS, Kim NK, Kim SH, Lee KY
Ann Surg 2023 Jul 1;278(1):31-38. Epub 2023 Jan 3 doi: 10.1097/SLA.0000000000005788. PMID: 36594748
The differential diagnosis and interdisciplinary treatment of anal carcinoma.
Raptis D, Schneider I, Matzel KE, Ott O, Fietkau R, Hohenberger W
Dtsch Arztebl Int 2015 Apr 3;112(14):243-9. doi: 10.3238/arztebl.2015.0243. PMID: 25891807Free PMC Article
Cancers of the anal canal: diagnosis, treatment and future strategies.
Bown E, Shah V, Sridhar T, Boyle K, Hemingway D, Yeung JM
Future Oncol 2014 Jun;10(8):1427-41. doi: 10.2217/fon.14.23. PMID: 25052753
Anal neoplasms.
Moore HG, Guillem JG
Surg Clin North Am 2002 Dec;82(6):1233-51. doi: 10.1016/s0039-6109(02)00057-9. PMID: 12516851

Therapy

Comparison of Laparoscopic Versus Robot-Assisted Surgery for Rectal Cancers: The COLRAR Randomized Controlled Trial.
Park JS, Lee SM, Choi GS, Park SY, Kim HJ, Song SH, Min BS, Kim NK, Kim SH, Lee KY
Ann Surg 2023 Jul 1;278(1):31-38. Epub 2023 Jan 3 doi: 10.1097/SLA.0000000000005788. PMID: 36594748
Robotic versus laparoscopic surgery for middle and low rectal cancer (REAL): short-term outcomes of a multicentre randomised controlled trial.
Feng Q, Yuan W, Li T, Tang B, Jia B, Zhou Y, Zhang W, Zhao R, Zhang C, Cheng L, Zhang X, Liang F, He G, Wei Y, Xu J; REAL Study Group
Lancet Gastroenterol Hepatol 2022 Nov;7(11):991-1004. Epub 2022 Sep 8 doi: 10.1016/S2468-1253(22)00248-5. PMID: 36087608
ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.
Damico N, Meyer J, Das P, Murphy J, Miller E, Koontz B, Hall W, McBride M, Pereira G, Catalano P, Chakravarthy AB, O'Dwyer PJ, Dorth J
Pract Radiat Oncol 2022 Jul-Aug;12(4):335-347. doi: 10.1016/j.prro.2022.01.015. PMID: 35717050
Neoadjuvant radiotherapy for rectal cancer management.
Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, Kerin M
World J Gastroenterol 2019 Sep 7;25(33):4850-4869. doi: 10.3748/wjg.v25.i33.4850. PMID: 31543678Free PMC Article
Next generation probiotics in disease amelioration.
Chang CJ, Lin TL, Tsai YL, Wu TR, Lai WF, Lu CC, Lai HC
J Food Drug Anal 2019 Jul;27(3):615-622. Epub 2019 Feb 2 doi: 10.1016/j.jfda.2018.12.011. PMID: 31324278Free PMC Article

Prognosis

The importance of MRI for rectal cancer evaluation.
Fernandes MC, Gollub MJ, Brown G
Surg Oncol 2022 Aug;43:101739. Epub 2022 Mar 18 doi: 10.1016/j.suronc.2022.101739. PMID: 35339339Free PMC Article
Surgical management of anal cancer.
Gilshtein H, Khoury W
Minerva Chir 2015 Apr;70(2):141-5. Epub 2015 Feb 18 PMID: 25690347
Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial.
van Gijn W, Marijnen CA, Nagtegaal ID, Kranenbarg EM, Putter H, Wiggers T, Rutten HJ, Påhlman L, Glimelius B, van de Velde CJ; Dutch Colorectal Cancer Group
Lancet Oncol 2011 Jun;12(6):575-82. Epub 2011 May 17 doi: 10.1016/S1470-2045(11)70097-3. PMID: 21596621
Anal neoplasms.
Moore HG, Guillem JG
Surg Clin North Am 2002 Dec;82(6):1233-51. doi: 10.1016/s0039-6109(02)00057-9. PMID: 12516851
Anal carcinoma.
Leichman LP, Cummings BJ
Curr Probl Cancer 1990 May-Jun;14(3):117-59. doi: 10.1016/0147-0272(90)90014-h. PMID: 2202554

Clinical prediction guides

A nomogram based on collagen signature for predicting the immunoscore in colorectal cancer.
Jiang W, Yu X, Dong X, Long C, Chen D, Cheng J, Yan B, Xu S, Lin Z, Chen G, Zhuo S, Yan J
Front Immunol 2023;14:1269700. Epub 2023 Sep 14 doi: 10.3389/fimmu.2023.1269700. PMID: 37781377Free PMC Article
The importance of MRI for rectal cancer evaluation.
Fernandes MC, Gollub MJ, Brown G
Surg Oncol 2022 Aug;43:101739. Epub 2022 Mar 18 doi: 10.1016/j.suronc.2022.101739. PMID: 35339339Free PMC Article
Use of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: Initial Results From the Pembrolizumab Arm of a Phase 2 Randomized Clinical Trial.
Rahma OE, Yothers G, Hong TS, Russell MM, You YN, Parker W, Jacobs SA, Colangelo LH, Lucas PC, Gollub MJ, Hall WA, Kachnic LA, Vijayvergia N, O'Rourke MA, Faller BA, Valicenti RK, Schefter TE, George S, Kainthla R, Stella PJ, Sigurdson E, Wolmark N, George TJ
JAMA Oncol 2021 Aug 1;7(8):1225-1230. doi: 10.1001/jamaoncol.2021.1683. PMID: 34196693Free PMC Article
Local excision and chemoradiation for clinical node-negative anal adenocarcinoma.
Chatani PD, Dominguez DA, Aversa JG, Davis JL, Hernandez JM, Lai LL, Blakely AM
Surg Oncol 2021 Jun;37:101551. Epub 2021 Mar 31 doi: 10.1016/j.suronc.2021.101551. PMID: 33819849Free PMC Article
Prospective Validation of a Low Rectal Cancer Magnetic Resonance Imaging Staging System and Development of a Local Recurrence Risk Stratification Model: The MERCURY II Study.
Battersby NJ, How P, Moran B, Stelzner S, West NP, Branagan G, Strassburg J, Quirke P, Tekkis P, Pedersen BG, Gudgeon M, Heald B, Brown G; MERCURY II Study Group
Ann Surg 2016 Apr;263(4):751-60. doi: 10.1097/SLA.0000000000001193. PMID: 25822672

Recent systematic reviews

Radiotherapy in the management of rare gastrointestinal cancers: A systematic review.
Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390
Robot-assisted TAMIS: a systematic review of feasibility and outcomes.
Jakobsen PCH, Krarup PM, Jensen KK, Nordholm-Carstensen A
Surg Endosc 2023 May;37(5):3398-3409. Epub 2023 Jan 27 doi: 10.1007/s00464-022-09853-z. PMID: 36707419Free PMC Article
State of the art treatment for stage I to III anal squamous cell carcinoma: A systematic review and meta-analysis.
Werner RN, Gaskins M, Avila Valle G, Budach V, Koswig S, Mosthaf FA, Raab HR, Rödel C, Nast A, Siegel R, Aigner F
Radiother Oncol 2021 Apr;157:188-196. Epub 2021 Feb 4 doi: 10.1016/j.radonc.2021.01.031. PMID: 33549645
Outcome following local excision of T1 anal cancers-a systematic review.
Pedersen TB, Kildsig J, Serup-Hansen E, Gocht-Jensen P, Klein MF
Int J Colorectal Dis 2020 Sep;35(9):1663-1671. Epub 2020 Jul 15 doi: 10.1007/s00384-020-03687-8. PMID: 32671458
Single-incision laparoscopic versus conventional laparoscopic right colectomy: A systematic review and meta-analysis.
Dong B, Luo Z, Lu J, Yang Y, Song Y, Cao J, Li W
Int J Surg 2018 Jul;55:31-38. Epub 2018 May 16 doi: 10.1016/j.ijsu.2018.05.013. PMID: 29777881

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