U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Conjunctival nevus

MedGen UID:
83422
•Concept ID:
C0346363
•
Neoplastic Process
Synonyms: Conjunctival Nevus; conjunctival nevus; Nevus of conjunctiva; Nevus of Conjunctiva; Nevus of the Conjunctiva; Nevus of the conjunctiva
SNOMED CT: Nevus of conjunctiva (255006004)
 
Monarch Initiative: MONDO:0006172

Definition

A benign melanocytic nevus that arises from the conjunctiva. [from NCI]

Professional guidelines

PubMed

Current Management of Conjunctival Melanoma Part 1: Clinical Features, Diagnosis and Histopathology.
Koç İ, Kıratlı H
Turk J Ophthalmol 2020 Oct 30;50(5):293-303. doi: 10.4274/tjo.galenos.2020.38096. PMID: 33342197Free PMC Article
Pathophysiology, diagnosis, and management of glaucoma associated with Sturge-Weber syndrome.
Javaid U, Ali MH, Jamal S, Butt NH
Int Ophthalmol 2018 Feb;38(1):409-416. Epub 2017 Jan 7 doi: 10.1007/s10792-016-0412-3. PMID: 28064423
Management of Primary Acquired Melanosis, Nevus, and Conjunctival Melanoma.
Kao A, Afshar A, Bloomer M, Damato B
Cancer Control 2016 Apr;23(2):117-25. doi: 10.1177/107327481602300205. PMID: 27218788

Recent clinical studies

Etiology

Conjunctival Autografts for Ocular Surface Reconstruction after Conjunctival Nevus Excision.
Ucar F
Cornea 2023 Oct 1;42(10):1206-1210. Epub 2022 Sep 28 doi: 10.1097/ICO.0000000000003117. PMID: 36731062
Clinical and immunohistopathological study of conjunctival melanocytic lesions in pediatric and adolescent patients. A case series.
Bogdănici CM, Costea CF, Dumitrescu GF, Sava A, Ciobanu Apostol DG, Scripcariu DV, Nicoară SD, Tănase DM, Andriescu EC, Cărăuleanu A, Danciu M, Sălăvăstru SC, Schmitzer S, Cucu AI, Niagu IA
Rom J Morphol Embryol 2021 Oct-Dec;62(4):907-915. doi: 10.47162/RJME.62.4.03. PMID: 35673810Free PMC Article
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Inflammatory juvenile compound conjunctival nevi. A clinicopathological study and literature review.
Costea CF, Turliuc MD, Dimitriu G, Bogdănici CM, MoŢoc A, Chihaia MA, Dancă C, Cucu A, Cărăuleanu A, Dumitrescu N, Indrei L, Turliuc Ş
Rom J Morphol Embryol 2017;58(3):739-747. PMID: 29250649
Giant conjunctival nevus: clinical features and natural course in 32 cases.
Shields CL, Regillo AC, Mellen PL, Kaliki S, Lally SE, Shields JA
JAMA Ophthalmol 2013 Jul;131(7):857-63. doi: 10.1001/jamaophthalmol.2013.160. PMID: 23702735

Diagnosis

Giant conjunctival nevus.
Irvine JA, Hsu HY, Mahdavi Fard A
Can J Ophthalmol 2023 Dec;58(6):e244. Epub 2023 Jun 19 doi: 10.1016/j.jcjo.2023.05.013. PMID: 37348840
Progress of Bulbar Conjunctival Microcirculation Alterations in the Diagnosis of Ocular Diseases.
Sun Z, Li Y, Liu R, Ma B, Zhou Y, Duan H, Bian L, Li W, Qi H
Dis Markers 2022;2022:4046809. Epub 2022 Aug 28 doi: 10.1155/2022/4046809. PMID: 36072898Free PMC Article
Giant conjunctival nevus.
Achibane A, Taouti H, Elmansouri O, Bannouk Y, Messoudi R, Kreit M, Arrab A, Rais H
J Fr Ophtalmol 2021 Nov;44(9):1457-1459. Epub 2021 Sep 30 doi: 10.1016/j.jfo.2021.01.038. PMID: 34602303
Conjunctival nevi and melanoma: multiparametric immunohistochemical analysis, including p16, SOX10, HMB45, and Ki-67.
Milman T, Zhang Q, Ang S, Elder D, Ida CM, Salomao DR, Lally SE, Shields JA, Hamershock RA, Sioufi K, Shields CL, Eagle RC Jr
Hum Pathol 2020 Sep;103:107-119. Epub 2020 Jul 21 doi: 10.1016/j.humpath.2020.07.020. PMID: 32707054
Giant conjunctival nevus: clinical features and natural course in 32 cases.
Shields CL, Regillo AC, Mellen PL, Kaliki S, Lally SE, Shields JA
JAMA Ophthalmol 2013 Jul;131(7):857-63. doi: 10.1001/jamaophthalmol.2013.160. PMID: 23702735

Therapy

Adopting low-shot deep learning for the detection of conjunctival melanoma using ocular surface images.
Yoo TK, Choi JY, Kim HK, Ryu IH, Kim JK
Comput Methods Programs Biomed 2021 Jun;205:106086. Epub 2021 Apr 3 doi: 10.1016/j.cmpb.2021.106086. PMID: 33862570
Efficacy of Pattern Scan Laser photocoagulation for superficial conjunctival nevi ablation.
Park YM, Lee JE, Lee JS
Lasers Med Sci 2016 Jul;31(5):1037-9. Epub 2016 Feb 25 doi: 10.1007/s10103-016-1915-x. PMID: 26914686
Ocular morbidity among primary school children of Dhulikhel, Nepal.
Sherpa D, Panta CR, Joshi N
Nepal J Ophthalmol 2011 Jul-Dec;3(2):172-6. doi: 10.3126/nepjoph.v3i2.5272. PMID: 21876593
Reconstruction of the ocular surface by transplantation of a serum-free derived cultivated conjunctival epithelial equivalent.
Tan DT, Ang LP, Beuerman RW
Transplantation 2004 Jun 15;77(11):1729-34. doi: 10.1097/01.tp.0000127593.65888.a6. PMID: 15201674

Prognosis

Conjunctival Autografts for Ocular Surface Reconstruction after Conjunctival Nevus Excision.
Ucar F
Cornea 2023 Oct 1;42(10):1206-1210. Epub 2022 Sep 28 doi: 10.1097/ICO.0000000000003117. PMID: 36731062
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Conjunctival nevi and melanoma: multiparametric immunohistochemical analysis, including p16, SOX10, HMB45, and Ki-67.
Milman T, Zhang Q, Ang S, Elder D, Ida CM, Salomao DR, Lally SE, Shields JA, Hamershock RA, Sioufi K, Shields CL, Eagle RC Jr
Hum Pathol 2020 Sep;103:107-119. Epub 2020 Jul 21 doi: 10.1016/j.humpath.2020.07.020. PMID: 32707054
Conjunctival Melanoma in Asian Indians: A Study of 42 Patients.
Kaliki S, Vasanthapuram VH, Mishra DK
Semin Ophthalmol 2019;34(3):182-187. Epub 2019 May 28 doi: 10.1080/08820538.2019.1620793. PMID: 31135259
Giant conjunctival nevus: clinical features and natural course in 32 cases.
Shields CL, Regillo AC, Mellen PL, Kaliki S, Lally SE, Shields JA
JAMA Ophthalmol 2013 Jul;131(7):857-63. doi: 10.1001/jamaophthalmol.2013.160. PMID: 23702735

Clinical prediction guides

Progress of Bulbar Conjunctival Microcirculation Alterations in the Diagnosis of Ocular Diseases.
Sun Z, Li Y, Liu R, Ma B, Zhou Y, Duan H, Bian L, Li W, Qi H
Dis Markers 2022;2022:4046809. Epub 2022 Aug 28 doi: 10.1155/2022/4046809. PMID: 36072898Free PMC Article
Clinical and immunohistopathological study of conjunctival melanocytic lesions in pediatric and adolescent patients. A case series.
Bogdănici CM, Costea CF, Dumitrescu GF, Sava A, Ciobanu Apostol DG, Scripcariu DV, Nicoară SD, Tănase DM, Andriescu EC, Cărăuleanu A, Danciu M, Sălăvăstru SC, Schmitzer S, Cucu AI, Niagu IA
Rom J Morphol Embryol 2021 Oct-Dec;62(4):907-915. doi: 10.47162/RJME.62.4.03. PMID: 35673810Free PMC Article
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Conjunctival nevi and melanoma: multiparametric immunohistochemical analysis, including p16, SOX10, HMB45, and Ki-67.
Milman T, Zhang Q, Ang S, Elder D, Ida CM, Salomao DR, Lally SE, Shields JA, Hamershock RA, Sioufi K, Shields CL, Eagle RC Jr
Hum Pathol 2020 Sep;103:107-119. Epub 2020 Jul 21 doi: 10.1016/j.humpath.2020.07.020. PMID: 32707054
Giant conjunctival nevus: clinical features and natural course in 32 cases.
Shields CL, Regillo AC, Mellen PL, Kaliki S, Lally SE, Shields JA
JAMA Ophthalmol 2013 Jul;131(7):857-63. doi: 10.1001/jamaophthalmol.2013.160. PMID: 23702735

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...