U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Iris nevus

MedGen UID:
83423
Concept ID:
C0346376
Neoplastic Process
Synonyms: Benign melanoma of iris; Eye freckle; Iris Nevus; Nevus of iris; Nevus of Iris; Nevus of the Iris
SNOMED CT: Benign melanoma of iris (95711003); Nevus of iris (95711003); Iris nevus (95711003)
 
HPO: HP:0011525

Definition

A benign brown pigmented area over the iris representing proliferation of melanocyte cells in the stromal layer of the iris. An iris nevus can be flat or occasionally slightly elevated. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIris nevus

Professional guidelines

PubMed

Cherkas E, Kalafatis NE, Marous MR, Shields CL
Clin Dermatol 2024 Jan-Feb;42(1):62-70. Epub 2023 Oct 21 doi: 10.1016/j.clindermatol.2023.10.009. PMID: 37865279
Shields JA, Sanborn GE, Augsburger JJ
Ophthalmology 1983 Jun;90(6):716-20. doi: 10.1016/s0161-6420(83)34500-0. PMID: 6888862

Recent clinical studies

Etiology

Cherkas E, Kalafatis NE, Marous MR, Shields CL
Clin Dermatol 2024 Jan-Feb;42(1):62-70. Epub 2023 Oct 21 doi: 10.1016/j.clindermatol.2023.10.009. PMID: 37865279
Oyemade KA, Xu TT, Lopez Dominguez J, Dumbrava MG, Hodge DO, White LJ, Dalvin LA
Br J Ophthalmol 2023 Sep;107(9):1369-1376. Epub 2022 Apr 21 doi: 10.1136/bjophthalmol-2021-320682. PMID: 35450938Free PMC Article
Yenice EK, Petriçli İS, Kara C
Arq Bras Oftalmol 2022;87(1):0536. Epub 2022 Jul 18 doi: 10.5935/0004-2749.2021-0536. PMID: 35857993
Shields CL, Kels JG, Shields JA
Clin Dermatol 2015 Mar-Apr;33(2):183-96. Epub 2015 Jan 14 doi: 10.1016/j.clindermatol.2014.10.010. PMID: 25704938
Schwab C, Zalaudek I, Mayer C, Riedl R, Wackernagel W, Juch H, Aigner B, Brunasso AM, Langmann G, Richtig E
Br J Ophthalmol 2015 May;99(5):644-9. Epub 2014 Oct 30 doi: 10.1136/bjophthalmol-2014-305849. PMID: 25359901

Diagnosis

Cherkas E, Kalafatis NE, Marous MR, Shields CL
Clin Dermatol 2024 Jan-Feb;42(1):62-70. Epub 2023 Oct 21 doi: 10.1016/j.clindermatol.2023.10.009. PMID: 37865279
Oyemade KA, Xu TT, Lopez Dominguez J, Dumbrava MG, Hodge DO, White LJ, Dalvin LA
Br J Ophthalmol 2023 Sep;107(9):1369-1376. Epub 2022 Apr 21 doi: 10.1136/bjophthalmol-2021-320682. PMID: 35450938Free PMC Article
Xavier C, Hipolito-Fernandes D, Cardigos J, Magriço A
BMJ Case Rep 2020 Dec 13;13(12) doi: 10.1136/bcr-2020-237269. PMID: 33318246Free PMC Article
Saldaña-Garrido JD, Martínez-Hergueta MC, Martínez-Rubio MM
Arch Soc Esp Oftalmol 2017 Jul;92(7):347-350. Epub 2016 Jun 1 doi: 10.1016/j.oftal.2016.04.005. PMID: 27262610
Mahdavi Fard A, Pourafkari L, Nader ND
QJM 2016 Feb;109(2):137. Epub 2015 Oct 1 doi: 10.1093/qjmed/hcv169. PMID: 26428339

Therapy

Grimaldos Ruiz P
Int Ophthalmol 2021 Apr;41(4):1381-1393. Epub 2021 Jan 23 doi: 10.1007/s10792-021-01693-5. PMID: 33484383Free PMC Article
Harley MR, Rao R, Lally SE, Shields CL
J AAPOS 2017 Aug;21(4):340-342. Epub 2017 Jun 16 doi: 10.1016/j.jaapos.2017.06.007. PMID: 28630029
Schwab C, Zalaudek I, Mayer C, Riedl R, Wackernagel W, Juch H, Aigner B, Brunasso AM, Langmann G, Richtig E
Br J Ophthalmol 2015 May;99(5):644-9. Epub 2014 Oct 30 doi: 10.1136/bjophthalmol-2014-305849. PMID: 25359901
Ozdemir Y, Onder F, Coşar CB, Usubütün A, Kural G
Acta Ophthalmol Scand 1999 Apr;77(2):234-7. doi: 10.1034/j.1600-0420.1999.770226.x. PMID: 10321548

Prognosis

Cherkas E, Kalafatis NE, Marous MR, Shields CL
Clin Dermatol 2024 Jan-Feb;42(1):62-70. Epub 2023 Oct 21 doi: 10.1016/j.clindermatol.2023.10.009. PMID: 37865279
Oyemade KA, Xu TT, Lopez Dominguez J, Dumbrava MG, Hodge DO, White LJ, Dalvin LA
Br J Ophthalmol 2023 Sep;107(9):1369-1376. Epub 2022 Apr 21 doi: 10.1136/bjophthalmol-2021-320682. PMID: 35450938Free PMC Article
Grimaldos Ruiz P
Int Ophthalmol 2021 Apr;41(4):1381-1393. Epub 2021 Jan 23 doi: 10.1007/s10792-021-01693-5. PMID: 33484383Free PMC Article
Xavier C, Hipolito-Fernandes D, Cardigos J, Magriço A
BMJ Case Rep 2020 Dec 13;13(12) doi: 10.1136/bcr-2020-237269. PMID: 33318246Free PMC Article
Shields CL, Kels JG, Shields JA
Clin Dermatol 2015 Mar-Apr;33(2):183-96. Epub 2015 Jan 14 doi: 10.1016/j.clindermatol.2014.10.010. PMID: 25704938

Clinical prediction guides

Cherkas E, Kalafatis NE, Marous MR, Shields CL
Clin Dermatol 2024 Jan-Feb;42(1):62-70. Epub 2023 Oct 21 doi: 10.1016/j.clindermatol.2023.10.009. PMID: 37865279
Grimaldos Ruiz P
Int Ophthalmol 2021 Apr;41(4):1381-1393. Epub 2021 Jan 23 doi: 10.1007/s10792-021-01693-5. PMID: 33484383Free PMC Article
Shields JA, Shields CL
Asia Pac J Ophthalmol (Phila) 2017 Jan-Feb;6(1):64-69. doi: 10.22608/APO.201613. PMID: 28161919
Saldaña-Garrido JD, Martínez-Hergueta MC, Martínez-Rubio MM
Arch Soc Esp Oftalmol 2017 Jul;92(7):347-350. Epub 2016 Jun 1 doi: 10.1016/j.oftal.2016.04.005. PMID: 27262610
Schwab C, Zalaudek I, Mayer C, Riedl R, Wackernagel W, Juch H, Aigner B, Brunasso AM, Langmann G, Richtig E
Br J Ophthalmol 2015 May;99(5):644-9. Epub 2014 Oct 30 doi: 10.1136/bjophthalmol-2014-305849. PMID: 25359901

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...