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Choroidal hemangioma

MedGen UID:
83424
Concept ID:
C0346390
Neoplastic Process
Synonym: Choroidal hemangiomata
SNOMED CT: Choroidal hemangioma (255022003); Hemangioma of choroid (255022003)
 
HPO: HP:0007872
Monarch Initiative: MONDO:0021542

Definition

The presence of multiple hemangiomas in the choroid. These are generally reddish or orange or can have increased pigmentation maiking them difficult to distinguish from choroidal melanomas. [from HPO]

Term Hierarchy

Conditions with this feature

Sturge-Weber syndrome
MedGen UID:
21361
Concept ID:
C0038505
Disease or Syndrome
Sturge-Weber syndrome is characterized by an intracranial vascular anomaly, leptomeningeal angiomatosis, most often involving the occipital and posterior parietal lobes. The most common symptoms and signs are facial cutaneous vascular malformations (port-wine stains), seizures, and glaucoma. Stasis results in ischemia underlying the leptomeningeal angiomatosis, leading to calcification and laminar cortical necrosis. The clinical course is highly variable and some children experience intractable seizures, mental retardation, and recurrent stroke-like episodes (review by Thomas-Sohl et al., 2004).

Professional guidelines

PubMed

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
Kumar A, Shankar S, Singh A, Mishra S, Kumar P, Arora A
Photodiagnosis Photodyn Ther 2022 Sep;39:103000. Epub 2022 Jul 3 doi: 10.1016/j.pdpdt.2022.103000. PMID: 35793781
Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430Free PMC Article

Recent clinical studies

Etiology

Sobol EK, Francis JH, Abramson DH, Freund KB, Spaide RF, Barbazetto I
Retina 2020 Apr;40(4):758-764. doi: 10.1097/IAE.0000000000002438. PMID: 30633085
Francis JH, Milman T, Grossniklaus H, Albert D, Folberg R, Levitin G, Coupland S, Catalanotti F, Rabady D, Kandoth C, Busam K, Abramson D
Ophthalmology 2019 May;126(5):759-763. Epub 2018 Dec 8 doi: 10.1016/j.ophtha.2018.12.011. PMID: 30537484Free PMC Article
Campagnoli TR, Medina CA, Singh AD
Retin Cases Brief Rep 2016 Spring;10(2):175-82. doi: 10.1097/ICB.0000000000000220. PMID: 26448544
Shields CL, Manalac J, Das C, Ferguson K, Shields JA
Curr Opin Ophthalmol 2014 May;25(3):177-85. doi: 10.1097/ICU.0000000000000041. PMID: 24614143
Baselga E
Semin Cutan Med Surg 2004 Jun;23(2):87-98. doi: 10.1016/j.sder.2004.01.002. PMID: 15295918

Diagnosis

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430Free PMC Article
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200
Baselga E
Semin Cutan Med Surg 2004 Jun;23(2):87-98. doi: 10.1016/j.sder.2004.01.002. PMID: 15295918
Shields CL, Shields JA, Augsburger JJ
Surv Ophthalmol 1988 Jul-Aug;33(1):17-27. doi: 10.1016/0039-6257(88)90069-0. PMID: 3051466

Therapy

Kumar A, Shankar S, Singh A, Mishra S, Kumar P, Arora A
Photodiagnosis Photodyn Ther 2022 Sep;39:103000. Epub 2022 Jul 3 doi: 10.1016/j.pdpdt.2022.103000. PMID: 35793781
Durrani AF, Zhou Y, Musch DC, Demirci H
Ophthalmol Retina 2022 Jun;6(6):533-535. Epub 2022 Feb 1 doi: 10.1016/j.oret.2022.01.015. PMID: 35114415
Pellegrini M, Staurenghi G, Mambretti M, Preziosa C
Retina 2022 Apr 1;42(4):767-774. doi: 10.1097/IAE.0000000000003373. PMID: 34861659
Sen M, Honavar SG
Indian J Ophthalmol 2019 Dec;67(12):1965-1973. doi: 10.4103/ijo.IJO_2036_19. PMID: 31755430Free PMC Article
Battaglia Parodi M, La Spina C, Berchicci L, Petruzzi G, Bandello F
Dev Ophthalmol 2016;55:330-6. Epub 2015 Oct 26 doi: 10.1159/000434704. PMID: 26501167

Prognosis

García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
Ganz JC
Prog Brain Res 2022;268(1):315-327. Epub 2021 Dec 14 doi: 10.1016/bs.pbr.2021.10.039. PMID: 35074088
Shields CL, Manalac J, Das C, Ferguson K, Shields JA
Curr Opin Ophthalmol 2014 May;25(3):177-85. doi: 10.1097/ICU.0000000000000041. PMID: 24614143
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200
Shields CL, Shields JA, Augsburger JJ
Surv Ophthalmol 1988 Jul-Aug;33(1):17-27. doi: 10.1016/0039-6257(88)90069-0. PMID: 3051466

Clinical prediction guides

Franco JJ, Liu KX, Ioakeim-Ioannidou M, Davila JR, Chen YL, Kim IK, Gragoudas ES, Mukai S, MacDonald SM
Pediatr Blood Cancer 2022 Dec;69(12):e29925. Epub 2022 Aug 21 doi: 10.1002/pbc.29925. PMID: 35989464
Sobol EK, Francis JH, Abramson DH, Freund KB, Spaide RF, Barbazetto I
Retina 2020 Apr;40(4):758-764. doi: 10.1097/IAE.0000000000002438. PMID: 30633085
Campagnoli TR, Medina CA, Singh AD
Retin Cases Brief Rep 2016 Spring;10(2):175-82. doi: 10.1097/ICB.0000000000000220. PMID: 26448544
Shields CL, Manalac J, Das C, Saktanasate J, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):117-21. doi: 10.4103/0301-4738.154377. PMID: 25827541Free PMC Article
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933

Recent systematic reviews

Zamir A, Hussain I, Ur Rehman A, Ashraf W, Imran I, Saeed H, Majeed A, Alqahtani F, Rasool MF
Clin Pharmacokinet 2022 Aug;61(8):1095-1114. Epub 2022 Jun 28 doi: 10.1007/s40262-022-01145-y. PMID: 35764772

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