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Metastatic Malignant Neoplasm in the Vagina

MedGen UID:
83435
Concept ID:
C0346997
Neoplastic Process
Synonyms: Cancer metastatic to vagina; Metastasis to the Vagina; Metastasis to vagina; Metastasis to Vagina; Metastatic malignant neoplasm of vagina; Metastatic Malignant Neoplasm to the Vagina; Metastatic malignant neoplasm to vagina; Metastatic Neoplasm to the Vagina; Secondary malignant neoplasm of vagina; Secondary Tumor to the Vagina; Secondary tumor to vagina; Secondary Tumor to Vagina
SNOMED CT: Secondary tumor to vagina (94668004); Metastasis to vagina (94668004); Secondary malignant neoplasm of vagina (94668004); Metastatic malignant neoplasm to vagina (94668004); Cancer metastatic to vagina (94668004); Metastatic malignant neoplasm of vagina (94668004)

Definition

A malignant neoplasm that has spread to the vagina from another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Vagina

Professional guidelines

PubMed

Expert Panel on GYN and OB Imaging, Kilcoyne A, Gottumukkala RV, Kang SK, Akin EA, Hauck C, Hindman NM, Huang C, Khanna N, Paspulati R, Rauch GM, Said T, Shinagare AB, Stein EB, Venkatesan AM, Maturen KE
J Am Coll Radiol 2021 Nov;18(11S):S442-S455. doi: 10.1016/j.jacr.2021.08.011. PMID: 34794599
Lanciotti L, Cofini M, Leonardi A, Bertozzi M, Penta L, Esposito S
Int J Environ Res Public Health 2019 Apr 9;16(7) doi: 10.3390/ijerph16071268. PMID: 30970592Free PMC Article
Faubion SS, Larkin LC, Stuenkel CA, Bachmann GA, Chism LA, Kagan R, Kaunitz AM, Krychman ML, Parish SJ, Partridge AH, Pinkerton JV, Rowen TS, Shapiro M, Simon JA, Goldfarb SB, Kingsberg SA
Menopause 2018 Jun;25(6):596-608. doi: 10.1097/GME.0000000000001121. PMID: 29762200

Recent clinical studies

Etiology

Adams TS, Rogers LJ, Cuello MA
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):19-27. doi: 10.1002/ijgo.13867. PMID: 34669198Free PMC Article
Faubion SS, Larkin LC, Stuenkel CA, Bachmann GA, Chism LA, Kagan R, Kaunitz AM, Krychman ML, Parish SJ, Partridge AH, Pinkerton JV, Rowen TS, Shapiro M, Simon JA, Goldfarb SB, Kingsberg SA
Menopause 2018 Jun;25(6):596-608. doi: 10.1097/GME.0000000000001121. PMID: 29762200
Stanley M
Hum Vaccin Immunother 2014;10(7):2109-11. doi: 10.4161/hv.29137. PMID: 25424825Free PMC Article
Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC
Lancet 2013 Sep 7;382(9895):889-99. Epub 2013 Apr 23 doi: 10.1016/S0140-6736(13)60022-7. PMID: 23618600
Castellsagué X
Gynecol Oncol 2008 Sep;110(3 Suppl 2):S4-7. doi: 10.1016/j.ygyno.2008.07.045. PMID: 18760711

Diagnosis

Adams TS, Rogers LJ, Cuello MA
Int J Gynaecol Obstet 2021 Oct;155 Suppl 1(Suppl 1):19-27. doi: 10.1002/ijgo.13867. PMID: 34669198Free PMC Article
Adams TS, Cuello MA
Int J Gynaecol Obstet 2018 Oct;143 Suppl 2:14-21. doi: 10.1002/ijgo.12610. PMID: 30306589
Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC
Lancet 2013 Sep 7;382(9895):889-99. Epub 2013 Apr 23 doi: 10.1016/S0140-6736(13)60022-7. PMID: 23618600
Buys SS, Partridge E, Black A, Johnson CC, Lamerato L, Isaacs C, Reding DJ, Greenlee RT, Yokochi LA, Kessel B, Crawford ED, Church TR, Andriole GL, Weissfeld JL, Fouad MN, Chia D, O'Brien B, Ragard LR, Clapp JD, Rathmell JM, Riley TL, Hartge P, Pinsky PF, Zhu CS, Izmirlian G, Kramer BS, Miller AB, Xu JL, Prorok PC, Gohagan JK, Berg CD; PLCO Project Team
JAMA 2011 Jun 8;305(22):2295-303. doi: 10.1001/jama.2011.766. PMID: 21642681
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777

Therapy

Stanley M
Hum Vaccin Immunother 2014;10(7):2109-11. doi: 10.4161/hv.29137. PMID: 25424825Free PMC Article
Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC
Lancet 2013 Sep 7;382(9895):889-99. Epub 2013 Apr 23 doi: 10.1016/S0140-6736(13)60022-7. PMID: 23618600
Buys SS, Partridge E, Black A, Johnson CC, Lamerato L, Isaacs C, Reding DJ, Greenlee RT, Yokochi LA, Kessel B, Crawford ED, Church TR, Andriole GL, Weissfeld JL, Fouad MN, Chia D, O'Brien B, Ragard LR, Clapp JD, Rathmell JM, Riley TL, Hartge P, Pinsky PF, Zhu CS, Izmirlian G, Kramer BS, Miller AB, Xu JL, Prorok PC, Gohagan JK, Berg CD; PLCO Project Team
JAMA 2011 Jun 8;305(22):2295-303. doi: 10.1001/jama.2011.766. PMID: 21642681
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777
Mansfield MJ, Emans SJ
J Reprod Med 1984 Jun;29(6):399-410. PMID: 6379175

Prognosis

Kelly ME, Heriot AG
Dis Colon Rectum 2023 Mar 1;66(3):355-357. Epub 2023 Jan 4 doi: 10.1097/DCR.0000000000002706. PMID: 36728599
Rajaram S, Maheshwari A, Srivastava A
Best Pract Res Clin Obstet Gynaecol 2015 Aug;29(6):822-32. Epub 2015 Mar 4 doi: 10.1016/j.bpobgyn.2015.01.006. PMID: 25847318
Buys SS, Partridge E, Black A, Johnson CC, Lamerato L, Isaacs C, Reding DJ, Greenlee RT, Yokochi LA, Kessel B, Crawford ED, Church TR, Andriole GL, Weissfeld JL, Fouad MN, Chia D, O'Brien B, Ragard LR, Clapp JD, Rathmell JM, Riley TL, Hartge P, Pinsky PF, Zhu CS, Izmirlian G, Kramer BS, Miller AB, Xu JL, Prorok PC, Gohagan JK, Berg CD; PLCO Project Team
JAMA 2011 Jun 8;305(22):2295-303. doi: 10.1001/jama.2011.766. PMID: 21642681
Nout RA, Smit VT, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LC, van der Steen-Banasik EM, Mens JW, Slot A, Kroese MC, van Bunningen BN, Ansink AC, van Putten WL, Creutzberg CL; PORTEC Study Group
Lancet 2010 Mar 6;375(9717):816-23. doi: 10.1016/S0140-6736(09)62163-2. PMID: 20206777
Lurain JR
Semin Surg Oncol 1990;6(6):347-53. doi: 10.1002/ssu.2980060610. PMID: 2175931

Clinical prediction guides

Kelly ME, Heriot AG
Dis Colon Rectum 2023 Mar 1;66(3):355-357. Epub 2023 Jan 4 doi: 10.1097/DCR.0000000000002706. PMID: 36728599
Manolea MM, Istrate-Ofiţeru AM, Săndulescu MS, Camen IV, Piciu IA, Dijmărescu AL, Vrabie SC, Neamţu SD, Obleagă CV, Siminel MA
Rom J Morphol Embryol 2022 Jul-Sep;63(3):511-520. doi: 10.47162/RJME.63.3.05. PMID: 36588489Free PMC Article
Wohlmuth C, Wohlmuth-Wieser I, Laframboise S
J Low Genit Tract Dis 2021 Apr 1;25(2):146-151. doi: 10.1097/LGT.0000000000000583. PMID: 33252450Free PMC Article
Wohlmuth C, Wohlmuth-Wieser I, May T, Vicus D, Gien LT, Laframboise S
Am J Clin Dermatol 2020 Apr;21(2):285-295. doi: 10.1007/s40257-019-00487-x. PMID: 31784896Free PMC Article
Lurain JR
Semin Surg Oncol 1990;6(6):347-53. doi: 10.1002/ssu.2980060610. PMID: 2175931

Recent systematic reviews

Guitarte C, Alagkiozidis I, Mize B, Stevens E, Salame G, Lee YC
Gynecol Oncol 2014 May;133(2):186-91. Epub 2014 Feb 4 doi: 10.1016/j.ygyno.2014.01.048. PMID: 24503463
Thomas LK, Bermejo JL, Vinokurova S, Jensen K, Bierkens M, Steenbergen R, Bergmann M, von Knebel Doeberitz M, Reuschenbach M
Eur J Cancer 2014 Jan;50(1):85-98. Epub 2013 Sep 17 doi: 10.1016/j.ejca.2013.08.022. PMID: 24054023
Kong A, Johnson N, Kitchener HC, Lawrie TA
J Natl Cancer Inst 2012 Nov 7;104(21):1625-34. Epub 2012 Sep 6 doi: 10.1093/jnci/djs374. PMID: 22962693
Medeiros LR, Rosa DD, da Rosa MI, Bozzetti MC, Zanini RR
Int J Gynecol Cancer 2009 Oct;19(7):1166-76. doi: 10.1111/IGC.0b013e3181a3d100. PMID: 19823051
Matsuo K, Eno ML, Im DD, Rosenshein NB
Am J Perinatol 2009 Aug;26(7):507-18. Epub 2009 Mar 13 doi: 10.1055/s-0029-1215428. PMID: 19288396

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