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Adult Mixed Cellularity Classic Hodgkin Lymphoma

MedGen UID:
83521
Concept ID:
C0279542
Neoplastic Process
Synonyms: Adult MCHD; Adult Mixed Cellularity Classical Hodgkin Lymphoma; Adult Mixed Cellularity Hodgkin Lymphoma; Adult Mixed Cellularity Hodgkin's Disease; Adult Mixed Cellularity Hodgkin's Lymphoma

Definition

Mixed cellularity classic Hodgkin lymphoma occurring in adults. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Mixed Cellularity Classic Hodgkin Lymphoma

Professional guidelines

PubMed

Al-Juhaishi T, Ahmed S
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):500-509. doi: 10.1182/hematology.2023000511. PMID: 38066938Free PMC Article
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Lewis WD, Lilly S, Jones KL
Am Fam Physician 2020 Jan 1;101(1):34-41. PMID: 31894937

Recent clinical studies

Etiology

Gupta S, Craig JW
Semin Diagn Pathol 2023 Nov;40(6):379-391. Epub 2023 Jun 30 doi: 10.1053/j.semdp.2023.06.005. PMID: 37451943
Eichenauer DA, Engert A
Blood 2020 Dec 24;136(26):2987-2993. doi: 10.1182/blood.2019004044. PMID: 32877522
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Fan Z, Natkunam Y, Bair E, Tibshirani R, Warnke RA
Am J Surg Pathol 2003 Oct;27(10):1346-56. doi: 10.1097/00000478-200310000-00007. PMID: 14508396
Yung L, Linch D
Lancet 2003 Mar 15;361(9361):943-51. doi: 10.1016/S0140-6736(03)12777-8. PMID: 12648984

Diagnosis

Pina-Oviedo S
Adv Anat Pathol 2021 Sep 1;28(5):307-334. doi: 10.1097/PAP.0000000000000305. PMID: 34074861
Eichenauer DA, Engert A
Blood 2020 Dec 24;136(26):2987-2993. doi: 10.1182/blood.2019004044. PMID: 32877522
Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL
Nat Rev Dis Primers 2020 Jul 23;6(1):61. doi: 10.1038/s41572-020-0189-6. PMID: 32703953
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Fan Z, Natkunam Y, Bair E, Tibshirani R, Warnke RA
Am J Surg Pathol 2003 Oct;27(10):1346-56. doi: 10.1097/00000478-200310000-00007. PMID: 14508396

Therapy

Fornecker LM, Lazarovici J, Aurer I, Casasnovas RO, Gac AC, Bonnet C, Bouabdallah K, Feugier P, Specht L, Molina L, Touati M, Borel C, Stamatoullas A, Nicolas-Virelizier E, Pascal L, Lugtenburg P, Di Renzo N, Vander Borght T, Traverse-Glehen A, Dartigues P, Hutchings M, Versari A, Meignan M, Federico M, André M; LYSA-FIL-EORTC Intergroup
J Clin Oncol 2023 Jan 10;41(2):327-335. Epub 2022 Jul 22 doi: 10.1200/JCO.21.01281. PMID: 35867960
Llaurador G, Giulino-Roth L
Curr Hematol Malig Rep 2021 Feb;16(1):61-71. Epub 2021 Mar 16 doi: 10.1007/s11899-021-00607-7. PMID: 33728589
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Yung L, Linch D
Lancet 2003 Mar 15;361(9361):943-51. doi: 10.1016/S0140-6736(03)12777-8. PMID: 12648984
Desforges JF, Rutherford CJ, Piro A
N Engl J Med 1979 Nov 29;301(22):1212-22. doi: 10.1056/NEJM197911293012205. PMID: 388217

Prognosis

Advani RH, Moskowitz AJ, Bartlett NL, Vose JM, Ramchandren R, Feldman TA, LaCasce AS, Christian BA, Ansell SM, Moskowitz CH, Brown L, Zhang C, Taft D, Ansari S, Sacchi M, Ho L, Herrera AF
Blood 2021 Aug 12;138(6):427-438. doi: 10.1182/blood.2020009178. PMID: 33827139
Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL
Nat Rev Dis Primers 2020 Jul 23;6(1):61. doi: 10.1038/s41572-020-0189-6. PMID: 32703953
Longley J, Johnson PWM
Br J Haematol 2019 Jan;184(1):60-71. Epub 2018 Nov 8 doi: 10.1111/bjh.15622. PMID: 30408156
Moskowitz CH, Walewski J, Nademanee A, Masszi T, Agura E, Holowiecki J, Abidi MH, Chen AI, Stiff P, Viviani S, Bachanova V, Sureda A, McClendon T, Lee C, Lisano J, Sweetenham J
Blood 2018 Dec 20;132(25):2639-2642. Epub 2018 Sep 28 doi: 10.1182/blood-2018-07-861641. PMID: 30266774
Medeiros LJ, Greiner TC
Cancer 1995 Jan 1;75(1 Suppl):357-69. doi: 10.1002/1097-0142(19950101)75:1+<357::aid-cncr2820751318>3.0.co;2-a. PMID: 8001007

Clinical prediction guides

Llaurador G, Giulino-Roth L
Curr Hematol Malig Rep 2021 Feb;16(1):61-71. Epub 2021 Mar 16 doi: 10.1007/s11899-021-00607-7. PMID: 33728589
Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL
Nat Rev Dis Primers 2020 Jul 23;6(1):61. doi: 10.1038/s41572-020-0189-6. PMID: 32703953
Townsend W, Linch D
Lancet 2012 Sep 1;380(9844):836-47. Epub 2012 Jul 25 doi: 10.1016/S0140-6736(12)60035-X. PMID: 22835602
Fan Z, Natkunam Y, Bair E, Tibshirani R, Warnke RA
Am J Surg Pathol 2003 Oct;27(10):1346-56. doi: 10.1097/00000478-200310000-00007. PMID: 14508396
Goldsmith SJ, Macapinlac HA, O'Brien JP
Semin Nucl Med 1995 Jul;25(3):262-71. doi: 10.1016/s0001-2998(95)80015-8. PMID: 7570045

Recent systematic reviews

Yasuda H, Yasuda M, Komatsu N
Cancer Sci 2021 Jul;112(7):2607-2624. Epub 2021 Jun 11 doi: 10.1111/cas.14933. PMID: 33938097Free PMC Article
Hill HA, Qi X, Jain P, Nomie K, Wang Y, Zhou S, Wang ML
Blood Adv 2020 Jul 14;4(13):2927-2938. doi: 10.1182/bloodadvances.2019001350. PMID: 32598477Free PMC Article
Kerbauy MN, Moraes FY, Lok BH, Ma J, Kerbauy LN, Spratt DE, Santos FP, Perini GF, Berlin A, Chung C, Hamerschlak N, Yahalom J
Radiother Oncol 2017 Mar;122(3):352-361. Epub 2017 Jan 16 doi: 10.1016/j.radonc.2016.12.033. PMID: 28104300
Dada R, Zekri J, Al Saadi R
Expert Opin Biol Ther 2016 Jun;16(6):739-45. Epub 2016 May 3 doi: 10.1080/14712598.2016.1180362. PMID: 27096887
Wolach O, Ram R
Acta Haematol 2014;132(3-4):279-91. Epub 2014 Sep 10 doi: 10.1159/000360212. PMID: 25228553

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