U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Good Prognosis Metastatic Gestational Trophoblastic Tumor

MedGen UID:
83655
•Concept ID:
C0280479
•
Neoplastic Process

Definition

Metastatic gestational trophoblastic tumor in which risk factors are absent. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGood Prognosis Metastatic Gestational Trophoblastic Tumor

Professional guidelines

PubMed

Primary treatment of stage IV gestational trophoblastic neoplasia with floxuridine, dactinomycin, etoposide and vincristine (FAEV): A report based on our 10-year clinical experiences.
Yang J, Xiang Y, Wan X, Feng F, Ren T
Gynecol Oncol 2016 Oct;143(1):68-72. Epub 2016 Jul 15 doi: 10.1016/j.ygyno.2016.07.099. PMID: 27426306
Management of brain metastases in patients with high-risk gestational trophoblastic tumors.
Newlands ES, Holden L, Seckl MJ, McNeish I, Strickland S, Rustin GJ
J Reprod Med 2002 Jun;47(6):465-71. PMID: 12092015
Effects of multiagent chemotherapy and independent risk factors in the treatment of high-risk GTT--25 years experiences of KRI-TRD.
Kim SJ, Bae SN, Kim JH, Kim CT, Han KT, Lee JM, Jung JK
Int J Gynaecol Obstet 1998 Apr;60 Suppl 1:S85-96. PMID: 9833620

Recent clinical studies

Etiology

Association between gestational trophoblastic disease (GTD) history and clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles.
Cai X, Zhang M, Huang C, Jiang Y, Zhou J, Xu M, Yan G, Sun H, Kong N
Reprod Biol Endocrinol 2022 Feb 4;20(1):27. doi: 10.1186/s12958-022-00898-2. PMID: 35120557Free PMC Article
Placental site trophoblastic tumor (PSTT) with multiple metastases and extremely poor prognosis.
Ohmaru T, Yamakawa H, Netsu S, Nokubi M, Konno R
Int J Clin Oncol 2009 Oct;14(5):452-6. Epub 2009 Oct 25 doi: 10.1007/s10147-008-0860-5. PMID: 19856056
Placental site trophoblastic tumour.
Kim SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):969-84. doi: 10.1016/s1521-6934(03)00095-6. PMID: 14614893
Recurrent gestational trophoblastic disease. Experience of the Southeastern Regional Trophoblastic Disease Center.
Mutch DG, Soper JT, Babcock CJ, Clarke-Pearson DL, Hammond CB
Cancer 1990 Sep 1;66(5):978-82. doi: 10.1002/1097-0142(19900901)66:5<978::aid-cncr2820660529>3.0.co;2-3. PMID: 2167150
Intensive inpatient therapy and survival in gestational trophoblastic disease.
Weed JC Jr, Jelovsek FR, Tyrey L, Hammond CB
Gynecol Oncol 1983 Jun;15(3):363-9. doi: 10.1016/0090-8258(83)90054-9. PMID: 6305783

Diagnosis

Association between gestational trophoblastic disease (GTD) history and clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles.
Cai X, Zhang M, Huang C, Jiang Y, Zhou J, Xu M, Yan G, Sun H, Kong N
Reprod Biol Endocrinol 2022 Feb 4;20(1):27. doi: 10.1186/s12958-022-00898-2. PMID: 35120557Free PMC Article
Placental Site Trophoblastic Tumor: A Distinct Entity of Gestational Trophoblastic Disease Experience from a Tertiary Referral Center in Hong Kong.
Chu MMY, Tse KY, Chan KKL, Cheung ANY, Ngan HYS
J Reprod Med 2016 Aug;61(7-8):351-356. PMID: 30408381
Placental site trophoblastic tumour.
Kim SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):969-84. doi: 10.1016/s1521-6934(03)00095-6. PMID: 14614893
Guidelines for the stratification of patients recruited to trials of therapy for low-risk gestational trophoblastic tumor.
Nevin J, Silcocks P, Hancock B, Coleman R, Nakielny R, Lorigan P
Gynecol Oncol 2000 Aug;78(2):92-6. doi: 10.1006/gyno.2000.5835. PMID: 10926786
Recurrent gestational trophoblastic disease. Experience of the Southeastern Regional Trophoblastic Disease Center.
Mutch DG, Soper JT, Babcock CJ, Clarke-Pearson DL, Hammond CB
Cancer 1990 Sep 1;66(5):978-82. doi: 10.1002/1097-0142(19900901)66:5<978::aid-cncr2820660529>3.0.co;2-3. PMID: 2167150

Therapy

Placental site trophoblastic tumor (PSTT) with multiple metastases and extremely poor prognosis.
Ohmaru T, Yamakawa H, Netsu S, Nokubi M, Konno R
Int J Clin Oncol 2009 Oct;14(5):452-6. Epub 2009 Oct 25 doi: 10.1007/s10147-008-0860-5. PMID: 19856056
Placental site trophoblastic tumour.
Kim SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):969-84. doi: 10.1016/s1521-6934(03)00095-6. PMID: 14614893
Guidelines for the stratification of patients recruited to trials of therapy for low-risk gestational trophoblastic tumor.
Nevin J, Silcocks P, Hancock B, Coleman R, Nakielny R, Lorigan P
Gynecol Oncol 2000 Aug;78(2):92-6. doi: 10.1006/gyno.2000.5835. PMID: 10926786
The role of operation in the current therapy of gestational trophoblastic disease.
Hammond CB, Weed JC Jr, Currie JL
Am J Obstet Gynecol 1980 Apr 1;136(7):844-58. doi: 10.1016/0002-9378(80)91041-8. PMID: 7361833
Treatment of metastatic trophoblastic disease: good and poor prognosis.
Hammond CB, Borchert LG, Tyrey L, Creasman WT, Parker RT
Am J Obstet Gynecol 1973 Feb 15;115(4):451-7. doi: 10.1016/0002-9378(73)90389-x. PMID: 4346614

Prognosis

Association between gestational trophoblastic disease (GTD) history and clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles.
Cai X, Zhang M, Huang C, Jiang Y, Zhou J, Xu M, Yan G, Sun H, Kong N
Reprod Biol Endocrinol 2022 Feb 4;20(1):27. doi: 10.1186/s12958-022-00898-2. PMID: 35120557Free PMC Article
Placental Site Trophoblastic Tumor: A Distinct Entity of Gestational Trophoblastic Disease Experience from a Tertiary Referral Center in Hong Kong.
Chu MMY, Tse KY, Chan KKL, Cheung ANY, Ngan HYS
J Reprod Med 2016 Aug;61(7-8):351-356. PMID: 30408381
Placental site trophoblastic tumor (PSTT) with multiple metastases and extremely poor prognosis.
Ohmaru T, Yamakawa H, Netsu S, Nokubi M, Konno R
Int J Clin Oncol 2009 Oct;14(5):452-6. Epub 2009 Oct 25 doi: 10.1007/s10147-008-0860-5. PMID: 19856056
Placental site trophoblastic tumour.
Kim SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):969-84. doi: 10.1016/s1521-6934(03)00095-6. PMID: 14614893
Recurrent gestational trophoblastic disease. Experience of the Southeastern Regional Trophoblastic Disease Center.
Mutch DG, Soper JT, Babcock CJ, Clarke-Pearson DL, Hammond CB
Cancer 1990 Sep 1;66(5):978-82. doi: 10.1002/1097-0142(19900901)66:5<978::aid-cncr2820660529>3.0.co;2-3. PMID: 2167150

Clinical prediction guides

Placental Site Trophoblastic Tumor: A Distinct Entity of Gestational Trophoblastic Disease Experience from a Tertiary Referral Center in Hong Kong.
Chu MMY, Tse KY, Chan KKL, Cheung ANY, Ngan HYS
J Reprod Med 2016 Aug;61(7-8):351-356. PMID: 30408381
Placental site trophoblastic tumour.
Kim SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):969-84. doi: 10.1016/s1521-6934(03)00095-6. PMID: 14614893
Clinical characteristics of gestational trophoblastic disease at a single institute.
Alici S, Eralp Y, Saip P, Argon A, Basaran M, Topuz E, Aydiner A
Tohoku J Exp Med 2002 Jun;197(2):95-100. doi: 10.1620/tjem.197.95. PMID: 12233789
Guidelines for the stratification of patients recruited to trials of therapy for low-risk gestational trophoblastic tumor.
Nevin J, Silcocks P, Hancock B, Coleman R, Nakielny R, Lorigan P
Gynecol Oncol 2000 Aug;78(2):92-6. doi: 10.1006/gyno.2000.5835. PMID: 10926786
Recurrent gestational trophoblastic disease. Experience of the Southeastern Regional Trophoblastic Disease Center.
Mutch DG, Soper JT, Babcock CJ, Clarke-Pearson DL, Hammond CB
Cancer 1990 Sep 1;66(5):978-82. doi: 10.1002/1097-0142(19900901)66:5<978::aid-cncr2820660529>3.0.co;2-3. PMID: 2167150

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...