U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pineal gland astrocytoma

MedGen UID:
83711
•Concept ID:
C0280795
•
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of pineal body; Astrocytoma of Pineal Gland; astrocytoma of pineal gland; Astrocytoma of the Pineal Gland; astrocytoma of the pineal gland; pineal astrocytic tumor; pineal astrocytic tumour; Pineal Astrocytoma; pineal astrocytoma; pineal body astrocytoma; pineal body astrocytoma (excluding glioblastoma); Pineal Gland Astrocytoma; pineal gland astrocytoma
 
Monarch Initiative: MONDO:0003171

Definition

A astrocytoma that involves the pineal body. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineal gland astrocytoma

Professional guidelines

PubMed

Results of the treatment of pineal tumors in children: the Lyon experience.
Szathmari A, Beuriat PA, Vasiljevic A, Leblond P, Faure-Conter C, Claude L, Di Rocco F, Mottolese C
Childs Nerv Syst 2023 Sep;39(9):2317-2327. Epub 2022 Oct 15 doi: 10.1007/s00381-022-05649-7. PMID: 36242638
Pineal Region Glioblastomas: Clinical Characteristics, Treatment, and Survival Outcome.
Niu X, Wang C, Zhou X, Yang Y, Liu Y, Zhang Y, Mao Q
World Neurosurg 2021 Feb;146:e799-e810. Epub 2020 Nov 10 doi: 10.1016/j.wneu.2020.11.016. PMID: 33186787
Management and outcome of low-grade astrocytomas of the midline in children: a retrospective review.
Hoffman HJ, Soloniuk DS, Humphreys RP, Drake JM, Becker LE, De Lima BO, Piatt JH Jr
Neurosurgery 1993 Dec;33(6):964-71. doi: 10.1227/00006123-199312000-00002. PMID: 8134009

Recent clinical studies

Etiology

Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Pathology of pineal parenchymal tumors.
Han SJ, Clark AJ, Ivan ME, Parsa AT, Perry A
Neurosurg Clin N Am 2011 Jul;22(3):335-40, vii. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.006. PMID: 21801981
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal tumors.
Dahiya S, Perry A
Adv Anat Pathol 2010 Nov;17(6):419-27. doi: 10.1097/PAP.0b013e3181f895a4. PMID: 20966647

Diagnosis

Imagery of pineal tumors.
Deiana G, Mottolese C, Hermier M, Louis-Tisserand G, Berthezene Y
Neurochirurgie 2015 Apr-Jun;61(2-3):113-22. Epub 2015 Feb 9 doi: 10.1016/j.neuchi.2014.10.111. PMID: 25676911
Pathology of pineal parenchymal tumors.
Han SJ, Clark AJ, Ivan ME, Parsa AT, Perry A
Neurosurg Clin N Am 2011 Jul;22(3):335-40, vii. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.006. PMID: 21801981
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal tumors.
Dahiya S, Perry A
Adv Anat Pathol 2010 Nov;17(6):419-27. doi: 10.1097/PAP.0b013e3181f895a4. PMID: 20966647
Pineal tumors.
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580

Therapy

Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Pediatric intracranial primary anaplastic ganglioglioma.
Lüdemann W, Banan R, Hartmann C, Bertalanffy H, Di Rocco C
Childs Nerv Syst 2017 Feb;33(2):227-231. Epub 2016 Dec 5 doi: 10.1007/s00381-016-3302-0. PMID: 27921213
Pineal calcification is associated with pediatric primary brain tumor.
Tuntapakul S, Kitkhuandee A, Kanpittaya J, Johns J, Johns NP
Asia Pac J Clin Oncol 2016 Dec;12(4):e405-e410. Epub 2016 Jul 27 doi: 10.1111/ajco.12519. PMID: 27461152
Radiosurgery/stereotactic external beam radiotherapy for malignant brain tumours: the Royal Marsden Hospital experience.
Brada M, Laing R
Recent Results Cancer Res 1994;135:91-104. doi: 10.1007/978-3-642-85039-4_10. PMID: 7519356
Management and outcome of low-grade astrocytomas of the midline in children: a retrospective review.
Hoffman HJ, Soloniuk DS, Humphreys RP, Drake JM, Becker LE, De Lima BO, Piatt JH Jr
Neurosurgery 1993 Dec;33(6):964-71. doi: 10.1227/00006123-199312000-00002. PMID: 8134009

Prognosis

Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Pineal Region Glioblastomas: Clinical Characteristics, Treatment, and Survival Outcome.
Niu X, Wang C, Zhou X, Yang Y, Liu Y, Zhang Y, Mao Q
World Neurosurg 2021 Feb;146:e799-e810. Epub 2020 Nov 10 doi: 10.1016/j.wneu.2020.11.016. PMID: 33186787
Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477
Pineal tumors.
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580

Clinical prediction guides

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Signaling the Unfolded Protein Response in primary brain cancers.
Le Reste PJ, Avril T, Quillien V, Morandi X, Chevet E
Brain Res 2016 Jul 1;1642:59-69. Epub 2016 Mar 23 doi: 10.1016/j.brainres.2016.03.015. PMID: 27016056
Pathology of pineal region tumors.
Hirato J, Nakazato Y
J Neurooncol 2001 Sep;54(3):239-49. doi: 10.1023/a:1012721723387. PMID: 11767290
Non-neoplastic pineal cysts.
Fetell MR, Bruce JN, Burke AM, Cross DT, Torres RA, Powers JM, Stein BM
Neurology 1991 Jul;41(7):1034-40. doi: 10.1212/wnl.41.7.1034. PMID: 2067630

Recent systematic reviews

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...