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Musculoskeletal Deformity

MedGen UID:
84298
•Concept ID:
C0281914
•
Anatomical Abnormality

Definition

Congenital or acquired deformity of the musculoskeletal system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMusculoskeletal Deformity

Professional guidelines

PubMed

Continuous postural management and the prevention of deformity in children with cerebral palsy: an appraisal.
Gough M
Dev Med Child Neurol 2009 Feb;51(2):105-10. doi: 10.1111/j.1469-8749.2008.03160.x. PMID: 19191843

Recent clinical studies

Etiology

Combined Bentall and Modified Ravitch Procedures: A Case Report and Systematic Review of the Evidence.
Taghizadeh Waghefi A, Petrov A, Wilbring M, Fajfrova Z, Fitze G, Matschke K, Kappert U
Medicina (Kaunas) 2022 Nov 30;58(12) doi: 10.3390/medicina58121774. PMID: 36556976Free PMC Article
Acquisition and loss of best walking skills in children and young people with bilateral cerebral palsy.
Baird G, Chandler S, Shortland A, Will E, Simonoff E, Scrutton D, Fairhurst C
Dev Med Child Neurol 2022 Feb;64(2):235-242. Epub 2021 Aug 19 doi: 10.1111/dmcn.15015. PMID: 34410016
Musculoskeletal deformities after thoracic surgery in children: An observational long-term follow-up study.
Safa N, Wei S, Saran N, Guadagno E, Laberge JM, Emil S
J Pediatr Surg 2021 Jan;56(1):136-141. Epub 2020 Oct 6 doi: 10.1016/j.jpedsurg.2020.09.024. PMID: 33168178
Progression to musculoskeletal deformity in childhood dystonia.
Lumsden DE, Gimeno H, Elze M, Tustin K, Kaminska M, Lin JP
Eur J Paediatr Neurol 2016 May;20(3):339-45. Epub 2016 Feb 19 doi: 10.1016/j.ejpn.2016.02.006. PMID: 26943984
Arthrodesis of the Charcot foot and ankle.
Baravarian B, Van Gils CC
Clin Podiatr Med Surg 2004 Apr;21(2):271-89. doi: 10.1016/j.cpm.2004.01.007. PMID: 15063884

Diagnosis

Bethlem Myopathy (Collagen VI-Related Dystrophies): A Retrospective Cohort Study on Musculoskeletal Pathologies and Clinical Course.
Silverstein RS, Wang DD, Haruno LS, Lotze TE, Scott AC, Rosenfeld SB
J Pediatr Orthop 2023 Feb 1;43(2):e163-e167. Epub 2022 Oct 26 doi: 10.1097/BPO.0000000000002283. PMID: 36607927
Acquisition and loss of best walking skills in children and young people with bilateral cerebral palsy.
Baird G, Chandler S, Shortland A, Will E, Simonoff E, Scrutton D, Fairhurst C
Dev Med Child Neurol 2022 Feb;64(2):235-242. Epub 2021 Aug 19 doi: 10.1111/dmcn.15015. PMID: 34410016
Growth profile assessment of young adults with tethered cord syndrome: a retrospective cohort analysis of Korean conscription data.
Lee SH, Shin HI, Nam TK, Park YS, Kim DK, Kwon JT
Childs Nerv Syst 2021 Jun;37(6):1973-1981. Epub 2021 Jan 3 doi: 10.1007/s00381-020-05026-2. PMID: 33392650
Progression to musculoskeletal deformity in childhood dystonia.
Lumsden DE, Gimeno H, Elze M, Tustin K, Kaminska M, Lin JP
Eur J Paediatr Neurol 2016 May;20(3):339-45. Epub 2016 Feb 19 doi: 10.1016/j.ejpn.2016.02.006. PMID: 26943984
Considerations and intervention in congenital muscular torticollis.
Suhr MC, Oledzka M
Curr Opin Pediatr 2015 Feb;27(1):75-81. doi: 10.1097/MOP.0000000000000175. PMID: 25565573

Therapy

Growth profile assessment of young adults with tethered cord syndrome: a retrospective cohort analysis of Korean conscription data.
Lee SH, Shin HI, Nam TK, Park YS, Kim DK, Kwon JT
Childs Nerv Syst 2021 Jun;37(6):1973-1981. Epub 2021 Jan 3 doi: 10.1007/s00381-020-05026-2. PMID: 33392650
Musculoskeletal deformities after thoracic surgery in children: An observational long-term follow-up study.
Safa N, Wei S, Saran N, Guadagno E, Laberge JM, Emil S
J Pediatr Surg 2021 Jan;56(1):136-141. Epub 2020 Oct 6 doi: 10.1016/j.jpedsurg.2020.09.024. PMID: 33168178
Musculoskeletal deformities following neonatal thoracotomy: long-term follow-up of an esophageal atresia cohort.
Wei S, Saran N, Emil S
J Pediatr Surg 2017 Dec;52(12):1898-1903. Epub 2017 Sep 5 doi: 10.1016/j.jpedsurg.2017.08.062. PMID: 28958717
Treatment of Blepharospasm in Schwartz-Jampel Syndrome: Botulinum Toxin A Injection or Surgery.
Kashkouli MB, Shahrzad S, Jazayeri AA, Abtahi MB
Ophthalmic Plast Reconstr Surg 2017 May/Jun;33(3S Suppl 1):S47-S49. doi: 10.1097/IOP.0000000000000503. PMID: 26020714
Proportion of life lived with dystonia inversely correlates with response to pallidal deep brain stimulation in both primary and secondary childhood dystonia.
Lumsden DE, Kaminska M, Gimeno H, Tustin K, Baker L, Perides S, Ashkan K, Selway R, Lin JP
Dev Med Child Neurol 2013 Jun;55(6):567-74. Epub 2013 Mar 1 doi: 10.1111/dmcn.12117. PMID: 23452222

Prognosis

Bethlem Myopathy (Collagen VI-Related Dystrophies): A Retrospective Cohort Study on Musculoskeletal Pathologies and Clinical Course.
Silverstein RS, Wang DD, Haruno LS, Lotze TE, Scott AC, Rosenfeld SB
J Pediatr Orthop 2023 Feb 1;43(2):e163-e167. Epub 2022 Oct 26 doi: 10.1097/BPO.0000000000002283. PMID: 36607927
Acquisition and loss of best walking skills in children and young people with bilateral cerebral palsy.
Baird G, Chandler S, Shortland A, Will E, Simonoff E, Scrutton D, Fairhurst C
Dev Med Child Neurol 2022 Feb;64(2):235-242. Epub 2021 Aug 19 doi: 10.1111/dmcn.15015. PMID: 34410016
Musculoskeletal deformities after thoracic surgery in children: An observational long-term follow-up study.
Safa N, Wei S, Saran N, Guadagno E, Laberge JM, Emil S
J Pediatr Surg 2021 Jan;56(1):136-141. Epub 2020 Oct 6 doi: 10.1016/j.jpedsurg.2020.09.024. PMID: 33168178
Genetics in orthopaedic practice.
Aicale R, Tarantino D, Maccauro G, Peretti GM, Maffulli N
J Biol Regul Homeost Agents 2019 Mar-Apr;33(2 Suppl. 1):103-117. XIX Congresso Nazionale S.I.C.O.O.P. Societa' Italiana Chirurghi Ortopedici Dell'ospedalita' Privata Accreditata. PMID: 31169010
Considerations and intervention in congenital muscular torticollis.
Suhr MC, Oledzka M
Curr Opin Pediatr 2015 Feb;27(1):75-81. doi: 10.1097/MOP.0000000000000175. PMID: 25565573

Clinical prediction guides

Acquisition and loss of best walking skills in children and young people with bilateral cerebral palsy.
Baird G, Chandler S, Shortland A, Will E, Simonoff E, Scrutton D, Fairhurst C
Dev Med Child Neurol 2022 Feb;64(2):235-242. Epub 2021 Aug 19 doi: 10.1111/dmcn.15015. PMID: 34410016
Increased Collagen Crosslinking in Stiff Clubfoot Tissue: Implications for the Improvement of Therapeutic Strategies.
Knitlova J, Doubkova M, Eckhardt A, Ostadal M, Musilkova J, Bacakova L, Novotny T
Int J Mol Sci 2021 Nov 2;22(21) doi: 10.3390/ijms222111903. PMID: 34769331Free PMC Article
Genetics in orthopaedic practice.
Aicale R, Tarantino D, Maccauro G, Peretti GM, Maffulli N
J Biol Regul Homeost Agents 2019 Mar-Apr;33(2 Suppl. 1):103-117. XIX Congresso Nazionale S.I.C.O.O.P. Societa' Italiana Chirurghi Ortopedici Dell'ospedalita' Privata Accreditata. PMID: 31169010
Foot and ankle characteristics in systemic lupus erythematosus: A systematic review and meta-analysis.
Stewart S, Brenton-Rule A, Dalbeth N, Aiyer A, Frampton C, Rome K
Semin Arthritis Rheum 2019 Apr;48(5):847-859. Epub 2018 Aug 6 doi: 10.1016/j.semarthrit.2018.07.002. PMID: 30093237
Considerations and intervention in congenital muscular torticollis.
Suhr MC, Oledzka M
Curr Opin Pediatr 2015 Feb;27(1):75-81. doi: 10.1097/MOP.0000000000000175. PMID: 25565573

Recent systematic reviews

Combined Bentall and Modified Ravitch Procedures: A Case Report and Systematic Review of the Evidence.
Taghizadeh Waghefi A, Petrov A, Wilbring M, Fajfrova Z, Fitze G, Matschke K, Kappert U
Medicina (Kaunas) 2022 Nov 30;58(12) doi: 10.3390/medicina58121774. PMID: 36556976Free PMC Article
Foot and ankle characteristics in systemic lupus erythematosus: A systematic review and meta-analysis.
Stewart S, Brenton-Rule A, Dalbeth N, Aiyer A, Frampton C, Rome K
Semin Arthritis Rheum 2019 Apr;48(5):847-859. Epub 2018 Aug 6 doi: 10.1016/j.semarthrit.2018.07.002. PMID: 30093237

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