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Complex renal cyst

MedGen UID:
852741
•Concept ID:
C0748283
•
Disease or Syndrome
Synonym: Complex Cyst of Kidney
SNOMED CT: Complex renal cyst (735471001)
 
HPO: HP:0032963

Definition

A renal cyst characterized by epithelium lined space (squamous/columnar) with septations. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComplex renal cyst

Professional guidelines

PubMed

Characterization and management of various renal cystic lesions by sonographic features.
Tay SY, Tiu CM, Hu B, Wang HK, Chiou HJ, Lin YH, Lai YC, Chan WP, Chou YH
J Chin Med Assoc 2018 Dec;81(12):1017-1026. Epub 2018 Jul 13 doi: 10.1016/j.jcma.2018.04.008. PMID: 30017809
Risk assessment of incidentally detected complex renal cysts in children: potential role for a modification of the Bosniak classification.
Wallis MC, Lorenzo AJ, Farhat WA, Bägli DJ, Khoury AE, Pippi Salle JL
J Urol 2008 Jul;180(1):317-21. Epub 2008 May 21 doi: 10.1016/j.juro.2008.03.063. PMID: 18499167

Recent clinical studies

Etiology

Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience.
Herms E, Weirich G, Maurer T, Wagenpfeil S, Preuss S, Sauter A, Heck M, Gärtner A, Hauner K, Autenrieth M, Kübler HP, Holzapfel K, Schwarz-Boeger U, Heemann U, Slotta-Huspenina J, Stock KF
World J Urol 2023 Mar;41(3):679-685. Epub 2022 Aug 20 doi: 10.1007/s00345-022-04094-0. PMID: 35986781Free PMC Article
Natural History of Complex Renal Cysts: Clinical Evidence Supporting Active Surveillance.
Chandrasekar T, Ahmad AE, Fadaak K, Jhaveri K, Bhatt JR, Jewett MAS, Finelli A
J Urol 2018 Mar;199(3):633-640. Epub 2017 Sep 20 doi: 10.1016/j.juro.2017.09.078. PMID: 28941915
Renal cyst formation in patients treated with crizotinib for non-small cell lung cancer-Incidence, radiological features and clinical characteristics.
Halpenny DF, McEvoy S, Li A, Hayan S, Capanu M, Zheng J, Riely G, Ginsberg MS
Lung Cancer 2017 Apr;106:33-36. Epub 2017 Jan 22 doi: 10.1016/j.lungcan.2017.01.010. PMID: 28285691Free PMC Article
Cystic renal masses.
Hindman NM
Abdom Radiol (NY) 2016 Jun;41(6):1020-34. doi: 10.1007/s00261-016-0761-4. PMID: 27154722
Renal imaging with ultrasound contrast: current status.
Robbin ML, Lockhart ME, Barr RG
Radiol Clin North Am 2003 Sep;41(5):963-78. doi: 10.1016/s0033-8389(03)00070-8. PMID: 14521204

Diagnosis

Fumarate hydratase-deficient renal cell carcinoma: a case report and review of the literature.
Lv Y, Song L, Hu M
J Med Case Rep 2023 Apr 20;17(1):182. doi: 10.1186/s13256-023-03841-0. PMID: 37076922Free PMC Article
Ultrasound-based "CEUS-Bosniak"classification for cystic renal lesions: an 8-year clinical experience.
Herms E, Weirich G, Maurer T, Wagenpfeil S, Preuss S, Sauter A, Heck M, Gärtner A, Hauner K, Autenrieth M, Kübler HP, Holzapfel K, Schwarz-Boeger U, Heemann U, Slotta-Huspenina J, Stock KF
World J Urol 2023 Mar;41(3):679-685. Epub 2022 Aug 20 doi: 10.1007/s00345-022-04094-0. PMID: 35986781Free PMC Article
Characterization and management of various renal cystic lesions by sonographic features.
Tay SY, Tiu CM, Hu B, Wang HK, Chiou HJ, Lin YH, Lai YC, Chan WP, Chou YH
J Chin Med Assoc 2018 Dec;81(12):1017-1026. Epub 2018 Jul 13 doi: 10.1016/j.jcma.2018.04.008. PMID: 30017809
Natural History of Complex Renal Cysts: Clinical Evidence Supporting Active Surveillance.
Chandrasekar T, Ahmad AE, Fadaak K, Jhaveri K, Bhatt JR, Jewett MAS, Finelli A
J Urol 2018 Mar;199(3):633-640. Epub 2017 Sep 20 doi: 10.1016/j.juro.2017.09.078. PMID: 28941915
Renal imaging with ultrasound contrast: current status.
Robbin ML, Lockhart ME, Barr RG
Radiol Clin North Am 2003 Sep;41(5):963-78. doi: 10.1016/s0033-8389(03)00070-8. PMID: 14521204

Therapy

Crizotinib-associated Renal Cyst Formation in a Pediatric Patient With ALK+ Epithelioid Inflammatory Myofibroblastic Sarcoma.
Kopelevich A, Holzman SA, La J, Lai HA, Torno L, Stephany HA
Urology 2021 Mar;149:222-224. Epub 2020 Sep 1 doi: 10.1016/j.urology.2020.08.032. PMID: 32882306
Development of complex renal cysts: A complication associated with Crizotinib therapy.
Chen F, Patel NJ, Legout JD, Caserta MP
Clin Imaging 2020 Sep;65:15-17. Epub 2020 Mar 31 doi: 10.1016/j.clinimag.2020.03.011. PMID: 32353713
A Complex Renal Cyst in a Patient on Crizotinib: Case Report.
Liaw CW, Palese M, Fabrizio LD
Urology 2019 Sep;131:21-23. Epub 2019 May 9 doi: 10.1016/j.urology.2019.04.035. PMID: 31078629
Renal cyst formation in patients treated with crizotinib for non-small cell lung cancer-Incidence, radiological features and clinical characteristics.
Halpenny DF, McEvoy S, Li A, Hayan S, Capanu M, Zheng J, Riely G, Ginsberg MS
Lung Cancer 2017 Apr;106:33-36. Epub 2017 Jan 22 doi: 10.1016/j.lungcan.2017.01.010. PMID: 28285691Free PMC Article
RETAINED GAUZE PIECE RESULTING IN RIGHT RENAL COMPLEX CYST DIAGNOSED AFTER 4 YEARS OF PYELOLITHOTOMY.
Arshad A, Zehra N, Malik H
J Ayub Med Coll Abbottabad 2015 Jan-Mar;27(1):243-4. PMID: 26182789

Prognosis

The Histopathologic Correlation of Bosniak 3 Cyst Subclassification.
Sefik E, Bozkurt IH, Adibelli ZH, Aydin ME, Celik S, Oguzdogan GY, Basmaci I, Gorgel SN, Vardar E, Gunlusoy B, Degirmenci T
Urology 2019 Jul;129:126-131. Epub 2019 Apr 19 doi: 10.1016/j.urology.2019.04.016. PMID: 31009744
Long-term oncological outcomes of cystic renal cell carcinoma according to the Bosniak classification.
Boissier R, Ouzaid I, Nouhaud FX, Khene Z, Dariane C, Chkir S, Chelly S, Giwerc A, Allenet C, Lefrancq JB, Gimel P, Bodin T, Rioux-Leclercq N, Correas JM, Albiges L, Hetet JF, Bigot P, Bernhard JC, Long JA, Mejean A, Bensalah K; AFU Committee of Urological Oncology
Int Urol Nephrol 2019 Jun;51(6):951-958. Epub 2019 Apr 12 doi: 10.1007/s11255-019-02085-6. PMID: 30977021
Natural History of Complex Renal Cysts: Clinical Evidence Supporting Active Surveillance.
Chandrasekar T, Ahmad AE, Fadaak K, Jhaveri K, Bhatt JR, Jewett MAS, Finelli A
J Urol 2018 Mar;199(3):633-640. Epub 2017 Sep 20 doi: 10.1016/j.juro.2017.09.078. PMID: 28941915
Renal cyst formation in patients treated with crizotinib for non-small cell lung cancer-Incidence, radiological features and clinical characteristics.
Halpenny DF, McEvoy S, Li A, Hayan S, Capanu M, Zheng J, Riely G, Ginsberg MS
Lung Cancer 2017 Apr;106:33-36. Epub 2017 Jan 22 doi: 10.1016/j.lungcan.2017.01.010. PMID: 28285691Free PMC Article
Renal imaging with ultrasound contrast: current status.
Robbin ML, Lockhart ME, Barr RG
Radiol Clin North Am 2003 Sep;41(5):963-78. doi: 10.1016/s0033-8389(03)00070-8. PMID: 14521204

Clinical prediction guides

The Modified Bosniak Classification for Intermediate-Risk Renal Cysts in Children.
Frumer M, Konen O, Shapira Rootman M, Soudack M, Ben-Shlush A, Ben-Meir D
Urology 2021 Mar;149:206-210. Epub 2020 Oct 28 doi: 10.1016/j.urology.2020.10.022. PMID: 33129869
Long-term oncological outcomes of cystic renal cell carcinoma according to the Bosniak classification.
Boissier R, Ouzaid I, Nouhaud FX, Khene Z, Dariane C, Chkir S, Chelly S, Giwerc A, Allenet C, Lefrancq JB, Gimel P, Bodin T, Rioux-Leclercq N, Correas JM, Albiges L, Hetet JF, Bigot P, Bernhard JC, Long JA, Mejean A, Bensalah K; AFU Committee of Urological Oncology
Int Urol Nephrol 2019 Jun;51(6):951-958. Epub 2019 Apr 12 doi: 10.1007/s11255-019-02085-6. PMID: 30977021
Risk assessment of incidentally detected complex renal cysts in children: potential role for a modification of the Bosniak classification.
Wallis MC, Lorenzo AJ, Farhat WA, Bägli DJ, Khoury AE, Pippi Salle JL
J Urol 2008 Jul;180(1):317-21. Epub 2008 May 21 doi: 10.1016/j.juro.2008.03.063. PMID: 18499167
Robotic-assisted laparoscopic partial nephrectomy: technique and initial clinical experience with DaVinci robotic system.
Gettman MT, Blute ML, Chow GK, Neururer R, Bartsch G, Peschel R
Urology 2004 Nov;64(5):914-8. doi: 10.1016/j.urology.2004.06.049. PMID: 15533477
Interplay of pregnancy, lactation, and hyperthyroidism leading to severe osteoporosis in a young woman.
Sekhar RV, Vassilopoulou-Sellin R
Endocr Pract 2001 Jul-Aug;7(4):262-6. doi: 10.4158/EP.7.4.262. PMID: 11497477

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