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Female Virilization

MedGen UID:
852908
•Concept ID:
C0865181
•
Disease or Syndrome

Definition

The development of male secondary sexual characteristics (such as hirsutism, deepening of the voice, or clitoral enlargement) in girls or adult females. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFemale Virilization

Professional guidelines

PubMed

Management of Growth Disorders in Puberty: GH, GnRHa, and Aromatase Inhibitors: A Clinical Review.
Mauras N, Ross J, Mericq V
Endocr Rev 2023 Jan 12;44(1):1-13. doi: 10.1210/endrev/bnac014. PMID: 35639981
Hirsutism in Polycystic Ovary Syndrome: Pathophysiology and Management.
Spritzer PM, Barone CR, Oliveira FB
Curr Pharm Des 2016;22(36):5603-5613. doi: 10.2174/1381612822666160720151243. PMID: 27510481
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME--PART 1.
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855

Recent clinical studies

Etiology

Prenatal treatment in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: up-date 88 of the French multicentric study.
Forest MG, Bétuel H, David M
Endocr Res 1989;15(1-2):277-301. doi: 10.1080/07435808909039101. PMID: 2667968

Diagnosis

A Dozen Testosterone Samples From One Patient, on One Day?
Foley KF
Lab Med 2021 Jan 4;52(1):e5-e7. doi: 10.1093/labmed/lmaa032. PMID: 32539123
Prenatal treatment in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: up-date 88 of the French multicentric study.
Forest MG, Bétuel H, David M
Endocr Res 1989;15(1-2):277-301. doi: 10.1080/07435808909039101. PMID: 2667968

Therapy

Prenatal treatment in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: up-date 88 of the French multicentric study.
Forest MG, Bétuel H, David M
Endocr Res 1989;15(1-2):277-301. doi: 10.1080/07435808909039101. PMID: 2667968

Clinical prediction guides

Binding of methyltrienolone to androgen receptors in human skin fibroblasts is enhanced by insulin.
Chang YT, Ghirri P, Migeon CJ, Brown TR
J Androl 1992 May-Jun;13(3):242-8. PMID: 1601743

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