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Gasping Syndrome

MedGen UID:
853789
•Concept ID:
C2609173
•
Sign or Symptom
Synonym: Neonatal Gasping Syndrome

Definition

A syndrome in preterm neonates exposed to benzyl alcohol preservative in intravascular solutions that is characterized by unremitting gasping respirations and may include anion gap metabolic acidosis, neurologic deterioration, renal failure, convulsions, intraventricular hemorrhage, and cardiovascular collapse. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGasping Syndrome

Professional guidelines

PubMed

A simple diagnostic scale based on the analysis and screening of clinical parameters in paediatric obstructive sleep apnoea hypopnea syndrome.
Wu D, Li X, Guo X, Qin J, Li S
J Laryngol Otol 2017 Apr;131(4):363-367. doi: 10.1017/S0022215117000238. PMID: 28244843
Continuous positive airway pressure for the treatment of obstructive sleep apnea.
Nurwidya F, Susanto AD, Juzar DA, Kobayashi I, Yunus F
Pneumologia 2016 Apr-Jun;65(2):72-5. PMID: 29539254

Recent clinical studies

Therapy

The gasping syndrome and benzyl alcohol poisoning.
Gershanik J, Boecler B, Ensley H, McCloskey S, George W
N Engl J Med 1982 Nov 25;307(22):1384-8. doi: 10.1056/NEJM198211253072206. PMID: 7133084

Clinical prediction guides

Developmental toxicity triggered by benzyl alcohol in the early stage of zebrafish embryos: Cardiovascular defects with inhibited liver formation and degenerated neurogenesis.
Manjunatha B, Sreevidya B, Lee SJ
Sci Total Environ 2021 Jan 15;752:141631. Epub 2020 Aug 15 doi: 10.1016/j.scitotenv.2020.141631. PMID: 32889257

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