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Memory dysfunction

MedGen UID:: 854406
•Concept ID:: C3887551
•: Mental or Behavioral Dysfunction

Synonym:	Memory Dysfunction
SNOMED CT:	Memory dysfunction (386807006)

Definition

Interference or disruption of memory processes. Memory dysfunction refers to the inability to store and retrieve information. This term encompasses a large number of problems and issues associated with intellectual functioning. 2005 [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMemory dysfunction

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Mental disorder
      - Memory dysfunction
        Memory impairment
        Long term memory impairment
        Anterograde amnesia
        Retrograde amnesia
        Progressive forgetfulness
        Short term memory impairment
        Deficit in phonologic short-term memory
        Transient global amnesia

Professional guidelines

PubMed

Pathophysiology and Treatment of Memory Dysfunction After Traumatic Brain Injury.

Paterno R, Folweiler KA, Cohen AS
Curr Neurol Neurosci Rep 2017 Jul;17(7):52. doi: 10.1007/s11910-017-0762-x. PMID: 28500417 Free PMC Article

Erythropoietin: a candidate treatment for mood symptoms and memory dysfunction in depression.

Miskowiak KW, Vinberg M, Harmer CJ, Ehrenreich H, Kessing LV
Psychopharmacology (Berl) 2012 Feb;219(3):687-98. Epub 2011 Sep 23 doi: 10.1007/s00213-011-2511-1. PMID: 21947319

The Korsakoff syndrome: clinical aspects, psychology and treatment.

Kopelman MD, Thomson AD, Guerrini I, Marshall EJ
Alcohol Alcohol 2009 Mar-Apr;44(2):148-54. Epub 2009 Jan 16 doi: 10.1093/alcalc/agn118. PMID: 19151162

See all (34)

Recent clinical studies

Etiology

The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease.

Barone E, Di Domenico F, Perluigi M, Butterfield DA
Free Radic Biol Med 2021 Nov 20;176:16-33. Epub 2021 Sep 14 doi: 10.1016/j.freeradbiomed.2021.09.006. PMID: 34530075 Free PMC Article

Post-Stroke Working Memory Dysfunction: A Meta-Analysis and Systematic Review.

Lugtmeijer S, Lammers NA, de Haan EHF, de Leeuw FE, Kessels RPC
Neuropsychol Rev 2021 Mar;31(1):202-219. Epub 2020 Nov 24 doi: 10.1007/s11065-020-09462-4. PMID: 33230717 Free PMC Article

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Investigation of rosemary herbal extracts (Rosmarinus officinalis) and their potential effects on immunity.

Ahmed HM, Babakir-Mina M
Phytother Res 2020 Aug;34(8):1829-1837. Epub 2020 Feb 22 doi: 10.1002/ptr.6648. PMID: 32086980

The psychosis spectrum in Parkinson disease.

Ffytche DH, Creese B, Politis M, Chaudhuri KR, Weintraub D, Ballard C, Aarsland D
Nat Rev Neurol 2017 Feb;13(2):81-95. Epub 2017 Jan 20 doi: 10.1038/nrneurol.2016.200. PMID: 28106066 Free PMC Article

See all (462)

Diagnosis

Memory Dysfunction.

Fernandez-Romero R, Spica DM
Continuum (Minneap Minn) 2021 Dec 1;27(6):1562-1585. doi: 10.1212/CON.0000000000001020. PMID: 34881726

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Memory Dysfunction.

Gliebus GP
Continuum (Minneap Minn) 2018 Jun;24(3, BEHAVIORAL NEUROLOGY AND PSYCHIATRY):727-744. doi: 10.1212/CON.0000000000000619. PMID: 29851875

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.

Ossenkoppele R, Pijnenburg YA, Perry DC, Cohn-Sheehy BI, Scheltens NM, Vogel JW, Kramer JH, van der Vlies AE, La Joie R, Rosen HJ, van der Flier WM, Grinberg LT, Rozemuller AJ, Huang EJ, van Berckel BN, Miller BL, Barkhof F, Jagust WJ, Scheltens P, Seeley WW, Rabinovici GD
Brain 2015 Sep;138(Pt 9):2732-49. Epub 2015 Jul 2 doi: 10.1093/brain/awv191. PMID: 26141491 Free PMC Article

Memory dysfunction.

Matthews BR
Continuum (Minneap Minn) 2015 Jun;21(3 Behavioral Neurology and Neuropsychiatry):613-26. doi: 10.1212/01.CON.0000466656.59413.29. PMID: 26039844 Free PMC Article

See all (355)

Therapy

Polygala tenuifolia: a source for anti-Alzheimer's disease drugs.

Deng X, Zhao S, Liu X, Han L, Wang R, Hao H, Jiao Y, Han S, Bai C
Pharm Biol 2020 Dec;58(1):410-416. doi: 10.1080/13880209.2020.1758732. PMID: 32429787 Free PMC Article

Investigation of rosemary herbal extracts (Rosmarinus officinalis) and their potential effects on immunity.

Ahmed HM, Babakir-Mina M
Phytother Res 2020 Aug;34(8):1829-1837. Epub 2020 Feb 22 doi: 10.1002/ptr.6648. PMID: 32086980

Baicalin mitigates cognitive impairment and protects neurons from microglia-mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF-κB signaling pathway.

Jin X, Liu MY, Zhang DF, Zhong X, Du K, Qian P, Yao WF, Gao H, Wei MJ
CNS Neurosci Ther 2019 May;25(5):575-590. Epub 2019 Jan 24 doi: 10.1111/cns.13086. PMID: 30676698 Free PMC Article

Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease.

Koch G, Bonnì S, Pellicciari MC, Casula EP, Mancini M, Esposito R, Ponzo V, Picazio S, Di Lorenzo F, Serra L, Motta C, Maiella M, Marra C, Cercignani M, Martorana A, Caltagirone C, Bozzali M
Neuroimage 2018 Apr 1;169:302-311. Epub 2017 Dec 19 doi: 10.1016/j.neuroimage.2017.12.048. PMID: 29277405

Sleep and epilepsy.

Bazil CW
Semin Neurol 2002 Sep;22(3):321-7. doi: 10.1055/s-2002-36651. PMID: 12528057

See all (223)

Prognosis

Mechanisms of cognitive impairment in temporal lobe epilepsy: A systematic review of resting-state functional connectivity studies.

Ives-Deliperi V, Butler JT
Epilepsy Behav 2021 Feb;115:107686. Epub 2020 Dec 24 doi: 10.1016/j.yebeh.2020.107686. PMID: 33360743

Memory Impairments and Psychosis Prediction: A Scoping Review and Theoretical Overview.

Seabury RD, Cannon TD
Neuropsychol Rev 2020 Dec;30(4):521-545. Epub 2020 Nov 23 doi: 10.1007/s11065-020-09464-2. PMID: 33226539

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs.

Niculescu AB, Le-Niculescu H, Roseberry K, Wang S, Hart J, Kaur A, Robertson H, Jones T, Strasburger A, Williams A, Kurian SM, Lamb B, Shekhar A, Lahiri DK, Saykin AJ
Mol Psychiatry 2020 Aug;25(8):1651-1672. Epub 2019 Dec 2 doi: 10.1038/s41380-019-0602-2. PMID: 31792364 Free PMC Article

Pharmacology of antidepressants.

Richelson E
Psychopathology 1987;20 Suppl 1:1-12. doi: 10.1159/000284517. PMID: 2892225

See all (217)

Clinical prediction guides

Mechanisms of cognitive impairment in temporal lobe epilepsy: A systematic review of resting-state functional connectivity studies.

Ives-Deliperi V, Butler JT
Epilepsy Behav 2021 Feb;115:107686. Epub 2020 Dec 24 doi: 10.1016/j.yebeh.2020.107686. PMID: 33360743

Neural oscillations and brain stimulation in Alzheimer's disease.

Jafari Z, Kolb BE, Mohajerani MH
Prog Neurobiol 2020 Nov;194:101878. Epub 2020 Jun 29 doi: 10.1016/j.pneurobio.2020.101878. PMID: 32615147

Development of the clinical assessment scale in autoimmune encephalitis.

Lim JA, Lee ST, Moon J, Jun JS, Kim TJ, Shin YW, Abdullah S, Byun JI, Sunwoo JS, Kim KT, Yang TW, Lee WJ, Moon HJ, Kim DW, Lim BC, Cho YW, Yang TH, Kim HJ, Kim YS, Koo YS, Park B, Jung KH, Kim M, Park KI, Jung KY, Chu K, Lee SK
Ann Neurol 2019 Mar;85(3):352-358. Epub 2019 Feb 10 doi: 10.1002/ana.25421. PMID: 30675918

Transcranial magnetic stimulation of the precuneus enhances memory and neural activity in prodromal Alzheimer's disease.

The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features.

See all (403)

Recent systematic reviews

An investigation of working memory deficits in depression using the n-back task: A systematic review and meta-analysis.

Nikolin S, Tan YY, Schwaab A, Moffa A, Loo CK, Martin D
J Affect Disord 2021 Apr 1;284:1-8. Epub 2021 Feb 5 doi: 10.1016/j.jad.2021.01.084. PMID: 33581489

Mechanisms of cognitive impairment in temporal lobe epilepsy: A systematic review of resting-state functional connectivity studies.

Ives-Deliperi V, Butler JT
Epilepsy Behav 2021 Feb;115:107686. Epub 2020 Dec 24 doi: 10.1016/j.yebeh.2020.107686. PMID: 33360743

Post-Stroke Working Memory Dysfunction: A Meta-Analysis and Systematic Review.

Lugtmeijer S, Lammers NA, de Haan EHF, de Leeuw FE, Kessels RPC
Neuropsychol Rev 2021 Mar;31(1):202-219. Epub 2020 Nov 24 doi: 10.1007/s11065-020-09462-4. PMID: 33230717 Free PMC Article

Episodic memory dysfunction in individuals at high-risk of psychosis: a systematic review of neuropsychological and neurofunctional studies.

Valli I, Tognin S, Fusar-Poli P, Mechelli A
Curr Pharm Des 2012;18(4):443-58. doi: 10.2174/138161212799316271. PMID: 22239575

Poststroke memory function in nondemented patients: a systematic review on frequency and neuroimaging correlates.

Snaphaan L, de Leeuw FE
Stroke 2007 Jan;38(1):198-203. Epub 2006 Dec 7 doi: 10.1161/01.STR.0000251842.34322.8f. PMID: 17158333

See all (10)

MedGen

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Memory dysfunction

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

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