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Autoimmune gastritis

MedGen UID:
854482
•Concept ID:
C3887639
•
Disease or Syndrome
Synonyms: Autoimmune Gastritis; autoimmune gastritis; autoimmune gastritis (disease)
SNOMED CT: Autoimmune gastritis (84568007)
 
Monarch Initiative: MONDO:0031014

Definition

Inflammation of the body fundic mucosa of the stomach. It results from the development of autoantibodies against the parietal and chief cells. It is associated with the presence of intestinal metaplasia and an increased risk of developing gastric carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAutoimmune gastritis

Professional guidelines

PubMed

AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Management of gastric and duodenal neuroendocrine tumors.
Sato Y, Hashimoto S, Mizuno K, Takeuchi M, Terai S
World J Gastroenterol 2016 Aug 14;22(30):6817-28. doi: 10.3748/wjg.v22.i30.6817. PMID: 27570419Free PMC Article
Autoimmune atrophic gastritis--pathogenesis, pathology and management.
Neumann WL, Coss E, Rugge M, Genta RM
Nat Rev Gastroenterol Hepatol 2013 Sep;10(9):529-41. Epub 2013 Jun 18 doi: 10.1038/nrgastro.2013.101. PMID: 23774773

Recent clinical studies

Etiology

Endoscopic features and clinical importance of autoimmune gastritis.
Kamada T, Maruyama Y, Monobe Y, Haruma K
Dig Endosc 2022 May;34(4):700-713. Epub 2021 Nov 10 doi: 10.1111/den.14175. PMID: 34674318
AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Gastritis, Gastric Polyps and Gastric Cancer.
Waldum H, Fossmark R
Int J Mol Sci 2021 Jun 18;22(12) doi: 10.3390/ijms22126548. PMID: 34207192Free PMC Article
Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis.
Hu S, Rayman MP
Thyroid 2017 May;27(5):597-610. Epub 2017 Apr 6 doi: 10.1089/thy.2016.0635. PMID: 28290237
Autoimmune atrophic gastritis--pathogenesis, pathology and management.
Neumann WL, Coss E, Rugge M, Genta RM
Nat Rev Gastroenterol Hepatol 2013 Sep;10(9):529-41. Epub 2013 Jun 18 doi: 10.1038/nrgastro.2013.101. PMID: 23774773

Diagnosis

Endoscopic features and clinical importance of autoimmune gastritis.
Kamada T, Maruyama Y, Monobe Y, Haruma K
Dig Endosc 2022 May;34(4):700-713. Epub 2021 Nov 10 doi: 10.1111/den.14175. PMID: 34674318
AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Autoimmune gastritis.
Lenti MV, Rugge M, Lahner E, Miceli E, Toh BH, Genta RM, De Block C, Hershko C, Di Sabatino A
Nat Rev Dis Primers 2020 Jul 9;6(1):56. doi: 10.1038/s41572-020-0187-8. PMID: 32647173
Autoimmune Gastritis.
Hall SN, Appelman HD
Arch Pathol Lab Med 2019 Nov;143(11):1327-1331. doi: 10.5858/arpa.2019-0345-RA. PMID: 31661309
Autoimmune atrophic gastritis--pathogenesis, pathology and management.
Neumann WL, Coss E, Rugge M, Genta RM
Nat Rev Gastroenterol Hepatol 2013 Sep;10(9):529-41. Epub 2013 Jun 18 doi: 10.1038/nrgastro.2013.101. PMID: 23774773

Therapy

Management of upper gastrointestinal symptoms in patients with autoimmune gastritis.
Gomez Cifuentes JD, Sparkman J, Graham DY
Curr Opin Gastroenterol 2022 Nov 1;38(6):600-606. Epub 2022 Sep 9 doi: 10.1097/MOG.0000000000000878. PMID: 36165039Free PMC Article
Claudin-18.
Wong MT, Singhi AD, Larson BK, Huynh CAT, Balzer BL, Burch M, Dhall D, Gangi A, Gong J, Guindi M, Hendifar AE, Kim SA, de Peralta-Venturina M, Waters KM
Arch Pathol Lab Med 2022 May 1;147(5):559-567. doi: 10.5858/arpa.2021-0428-OA. PMID: 35976638
Functional Dyspepsia in the Elderly.
Walker MM, Talley NJ
Curr Gastroenterol Rep 2019 Nov 13;21(10):54. doi: 10.1007/s11894-019-0722-5. PMID: 31720909
Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease.
Rayman MP
Proc Nutr Soc 2019 Feb;78(1):34-44. Epub 2018 Sep 13 doi: 10.1017/S0029665118001192. PMID: 30208979
Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis.
Hu S, Rayman MP
Thyroid 2017 May;27(5):597-610. Epub 2017 Apr 6 doi: 10.1089/thy.2016.0635. PMID: 28290237

Prognosis

Research status and hotspots of autoimmune gastritis: A bibliometric analysis.
Yu YF, Tong KK, Shangguan XL, Yang XY, Wu JY, Hu G, Yu R, Tan CC
World J Gastroenterol 2023 Nov 14;29(42):5781-5799. doi: 10.3748/wjg.v29.i42.5781. PMID: 38075850Free PMC Article
Autoimmune gastritis: long-term natural history in naïve Helicobacter pylori-negative patients.
Rugge M, Bricca L, Guzzinati S, Sacchi D, Pizzi M, Savarino E, Farinati F, Zorzi M, Fassan M, Dei Tos AP, Malfertheiner P, Genta RM, Graham DY
Gut 2023 Jan;72(1):30-38. Epub 2022 Jun 30 doi: 10.1136/gutjnl-2022-327827. PMID: 35772926
AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Gastritis: The clinico-pathological spectrum.
Rugge M, Savarino E, Sbaraglia M, Bricca L, Malfertheiner P
Dig Liver Dis 2021 Oct;53(10):1237-1246. Epub 2021 Mar 28 doi: 10.1016/j.dld.2021.03.007. PMID: 33785282
Gastric Carcinoids.
Grozinsky-Glasberg S, Alexandraki KI, Angelousi A, Chatzellis E, Sougioultzis S, Kaltsas G
Endocrinol Metab Clin North Am 2018 Sep;47(3):645-660. Epub 2018 Jul 11 doi: 10.1016/j.ecl.2018.04.013. PMID: 30098721

Clinical prediction guides

Autoimmune gastritis: long-term natural history in naïve Helicobacter pylori-negative patients.
Rugge M, Bricca L, Guzzinati S, Sacchi D, Pizzi M, Savarino E, Farinati F, Zorzi M, Fassan M, Dei Tos AP, Malfertheiner P, Genta RM, Graham DY
Gut 2023 Jan;72(1):30-38. Epub 2022 Jun 30 doi: 10.1136/gutjnl-2022-327827. PMID: 35772926
AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.
Shah SC, Piazuelo MB, Kuipers EJ, Li D
Gastroenterology 2021 Oct;161(4):1325-1332.e7. Epub 2021 Aug 26 doi: 10.1053/j.gastro.2021.06.078. PMID: 34454714Free PMC Article
Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease.
Rayman MP
Proc Nutr Soc 2019 Feb;78(1):34-44. Epub 2018 Sep 13 doi: 10.1017/S0029665118001192. PMID: 30208979
Multiple Nutritional Factors and the Risk of Hashimoto's Thyroiditis.
Hu S, Rayman MP
Thyroid 2017 May;27(5):597-610. Epub 2017 Apr 6 doi: 10.1089/thy.2016.0635. PMID: 28290237
Autoimmune gastritis: Pathologist's viewpoint.
Coati I, Fassan M, Farinati F, Graham DY, Genta RM, Rugge M
World J Gastroenterol 2015 Nov 14;21(42):12179-89. doi: 10.3748/wjg.v21.i42.12179. PMID: 26576102Free PMC Article

Recent systematic reviews

A Systematic Review of Symptoms of Pernicious Anemia.
Seage CH, Bennett A, Ward N, Semedo L, Plattel CHM, Suijker KIM, Vis JY, James DH
Food Nutr Bull 2024 Jun;45(1_suppl):S34-S39. doi: 10.1177/03795721241227016. PMID: 38987871
Helicobacter pylori-negative Chronic Gastritis in Children: A Systematic Review.
Assa A, Borrelli O, Broekaert I, Saccomani MD, Dolinsek J, Martin-de-Carpi J, Mas E, Miele E, Sila S, Thomson M, Tzivinikos C, Benninga MA; Gastrointestinal Committee of ESPGHAN
J Pediatr Gastroenterol Nutr 2022 May 1;74(5):956-967. Epub 2022 Feb 16 doi: 10.1097/MPG.0000000000003414. PMID: 35175996
Prevalence of latent and overt polyautoimmunity in autoimmune thyroid disease: A systematic review and meta-analysis.
Botello A, Herrán M, Salcedo V, Rodríguez Y, Anaya JM, Rojas M
Clin Endocrinol (Oxf) 2020 Oct;93(4):375-389. Epub 2020 Aug 13 doi: 10.1111/cen.14304. PMID: 32738825
Autoimmune Diseases and Gastric Cancer Risk: A Systematic Review and Meta-Analysis.
Song M, Latorre G, Ivanovic-Zuvic D, Camargo MC, Rabkin CS
Cancer Res Treat 2019 Jul;51(3):841-850. Epub 2019 May 3 doi: 10.4143/crt.2019.151. PMID: 31048663Free PMC Article
Incidence of cancer (other than gastric cancer) in pernicious anaemia: A systematic review with meta-analysis.
Lahner E, Capasso M, Carabotti M, Annibale B
Dig Liver Dis 2018 Aug;50(8):780-786. Epub 2018 May 24 doi: 10.1016/j.dld.2018.05.012. PMID: 29887343

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