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Cataract 32(CTRCT32)

MedGen UID:
854634
Concept ID:
C3887926
Disease or Syndrome
Synonyms: Anterior polar cataracts 1; CATARACT 32, MULTIPLE TYPES; Cataract anterior polar dominant; CATARACT, ANTERIOR POLAR, 1; Cataract, posterior polar, 5; CTRCT32
 
Monarch Initiative: MONDO:0007278
OMIM®: 115650

Definition

A cataract that has material basis in mutation in the region 14q22-q23. [from MONDO]

Clinical features

From HPO
Early-onset anterior polar cataract
MedGen UID:
340806
Concept ID:
C1855179
Congenital Abnormality
A polar cataract that affects the anterior pole of the lens.

Professional guidelines

PubMed

Mistr SK, Trivedi RH, Wilson ME
J AAPOS 2008 Feb;12(1):58-61. Epub 2007 Oct 29 doi: 10.1016/j.jaapos.2007.08.003. PMID: 18029213
Dunn AS, Turpie AG
Arch Intern Med 2003 Apr 28;163(8):901-8. doi: 10.1001/archinte.163.8.901. PMID: 12719198

Recent clinical studies

Etiology

Zhang S, Chen J, Yang F, Xu B, Tang Y, Lu Y
Br J Ophthalmol 2023 May;107(5):683-689. Epub 2022 Jan 27 doi: 10.1136/bjophthalmol-2021-319991. PMID: 35086805
Vergroesen JE, Thee EF, Ahmadizar F, van Duijn CM, Stricker BH, Kavousi M, Klaver CCW, Ramdas WD
JAMA Ophthalmol 2022 Jul 1;140(7):674-681. doi: 10.1001/jamaophthalmol.2022.1435. PMID: 35587864Free PMC Article
Xia Y
J Perioper Pract 2022 Dec;32(12):361-367. Epub 2022 Apr 21 doi: 10.1177/17504589221091063. PMID: 35445624
Ahmed IIK, De Francesco T, Rhee D, McCabe C, Flowers B, Gazzard G, Samuelson TW, Singh K; HORIZON Investigators
Ophthalmology 2022 Jul;129(7):742-751. Epub 2022 Feb 23 doi: 10.1016/j.ophtha.2022.02.021. PMID: 35218867
Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW
Invest Ophthalmol Vis Sci 2020 Apr 9;61(4):49. doi: 10.1167/iovs.61.4.49. PMID: 32347918Free PMC Article

Diagnosis

Gazzard G, Konstantakopoulou E, Garway-Heath D, Adeleke M, Vickerstaff V, Ambler G, Hunter R, Bunce C, Nathwani N, Barton K; LiGHT Trial Study Group
Ophthalmology 2023 Feb;130(2):139-151. Epub 2022 Sep 17 doi: 10.1016/j.ophtha.2022.09.009. PMID: 36122660
Arriola-Villalobos P, Moll-Udina A, Carrasco-López-Brea M, Sacristan C, Capella MJ, Peiteado D, Garrote-Llordén A, Albert Fort M, Jódar Márquez M, Jacobo Gonzalez Guijarro J, Demetrio-Pablo R, Luis Sánchez Sevilla J, Carreño E, González-López J, Miguel-Escuder L, Cuadros C, Díaz-Valle D, Adan A; Contributors: VKH Spanish Study Group, Benítez Del Castillo JM, Fonollosa A, Cordero M, Martínez Costa L, Blanco-Alonso R
Eur J Ophthalmol 2022 May;32(3):1547-1554. Epub 2021 Jul 16 doi: 10.1177/11206721211033477. PMID: 34269103
Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW
Invest Ophthalmol Vis Sci 2020 Apr 9;61(4):49. doi: 10.1167/iovs.61.4.49. PMID: 32347918Free PMC Article
Clemmensen K, Enghild JJ, Ivarsen A, Riise R, Vorum H, Heegaard S
Graefes Arch Clin Exp Ophthalmol 2017 Jan;255(1):119-125. Epub 2016 Nov 5 doi: 10.1007/s00417-016-3539-z. PMID: 27817115
Davenport KM, Patel AA
Pediatr Rev 2011 Feb;32(2):82-3. doi: 10.1542/pir.32-2-82. PMID: 21285306

Therapy

Bénard A, Sitta R, Brezin AP, Cochener B, Monnet D, Denis P, Pisella PJ, Hayes N, Schweitzer C; FEMCAT Study Group
JAMA Ophthalmol 2023 Jul 1;141(7):625-629. doi: 10.1001/jamaophthalmol.2023.1716. PMID: 37200037Free PMC Article
Gazzard G, Konstantakopoulou E, Garway-Heath D, Adeleke M, Vickerstaff V, Ambler G, Hunter R, Bunce C, Nathwani N, Barton K; LiGHT Trial Study Group
Ophthalmology 2023 Feb;130(2):139-151. Epub 2022 Sep 17 doi: 10.1016/j.ophtha.2022.09.009. PMID: 36122660
Zhang S, Chen J, Yang F, Xu B, Tang Y, Lu Y
Br J Ophthalmol 2023 May;107(5):683-689. Epub 2022 Jan 27 doi: 10.1136/bjophthalmol-2021-319991. PMID: 35086805
Ahmed IIK, De Francesco T, Rhee D, McCabe C, Flowers B, Gazzard G, Samuelson TW, Singh K; HORIZON Investigators
Ophthalmology 2022 Jul;129(7):742-751. Epub 2022 Feb 23 doi: 10.1016/j.ophtha.2022.02.021. PMID: 35218867
Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW
Invest Ophthalmol Vis Sci 2020 Apr 9;61(4):49. doi: 10.1167/iovs.61.4.49. PMID: 32347918Free PMC Article

Prognosis

Wang Q, Zhang S, Wang Y, Zhao D, Zhou C
JMIR Public Health Surveill 2022 Nov 14;8(11):e39314. doi: 10.2196/39314. PMID: 36374533Free PMC Article
Liu PK, Chang YC, Wang NK, Ryu J, Tsai RK, Hsu SL, Hung JY, Hsu CY, Tai MH, Tsai MJ
J Clin Sleep Med 2022 Mar 1;18(3):769-777. doi: 10.5664/jcsm.9714. PMID: 34633283Free PMC Article
Arriola-Villalobos P, Moll-Udina A, Carrasco-López-Brea M, Sacristan C, Capella MJ, Peiteado D, Garrote-Llordén A, Albert Fort M, Jódar Márquez M, Jacobo Gonzalez Guijarro J, Demetrio-Pablo R, Luis Sánchez Sevilla J, Carreño E, González-López J, Miguel-Escuder L, Cuadros C, Díaz-Valle D, Adan A; Contributors: VKH Spanish Study Group, Benítez Del Castillo JM, Fonollosa A, Cordero M, Martínez Costa L, Blanco-Alonso R
Eur J Ophthalmol 2022 May;32(3):1547-1554. Epub 2021 Jul 16 doi: 10.1177/11206721211033477. PMID: 34269103
Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW
Invest Ophthalmol Vis Sci 2020 Apr 9;61(4):49. doi: 10.1167/iovs.61.4.49. PMID: 32347918Free PMC Article
Sheeladevi S, Lawrenson JG, Fielder AR, Suttle CM
Eye (Lond) 2016 Sep;30(9):1160-9. Epub 2016 Aug 12 doi: 10.1038/eye.2016.156. PMID: 27518543Free PMC Article

Clinical prediction guides

Gazzard G, Konstantakopoulou E, Garway-Heath D, Adeleke M, Vickerstaff V, Ambler G, Hunter R, Bunce C, Nathwani N, Barton K; LiGHT Trial Study Group
Ophthalmology 2023 Feb;130(2):139-151. Epub 2022 Sep 17 doi: 10.1016/j.ophtha.2022.09.009. PMID: 36122660
Wang Q, Zhang S, Wang Y, Zhao D, Zhou C
JMIR Public Health Surveill 2022 Nov 14;8(11):e39314. doi: 10.2196/39314. PMID: 36374533Free PMC Article
Kovaleva EV, Eremkina AK, Elfimova AR, Krupinova JA, Bibik EE, Maganeva IS, Gorbacheva AM, Dobreva EA, Melnichenko GA, Mokrysheva NG
Front Endocrinol (Lausanne) 2022;13:800119. Epub 2022 Feb 16 doi: 10.3389/fendo.2022.800119. PMID: 35250859Free PMC Article
GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e130-e143. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30425-3. PMID: 33275950Free PMC Article
GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e144-e160. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30489-7. PMID: 33275949Free PMC Article

Recent systematic reviews

GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e130-e143. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30425-3. PMID: 33275950Free PMC Article
GBD 2019 Blindness and Vision Impairment Collaborators; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2021 Feb;9(2):e144-e160. Epub 2020 Dec 1 doi: 10.1016/S2214-109X(20)30489-7. PMID: 33275949Free PMC Article
Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW
Invest Ophthalmol Vis Sci 2020 Apr 9;61(4):49. doi: 10.1167/iovs.61.4.49. PMID: 32347918Free PMC Article
Rice JB, White AG, Scarpati LM, Wan G, Nelson WW
Clin Ther 2017 Nov;39(11):2216-2229. Epub 2017 Oct 19 doi: 10.1016/j.clinthera.2017.09.011. PMID: 29055500
Flaxman SR, Bourne RRA, Resnikoff S, Ackland P, Braithwaite T, Cicinelli MV, Das A, Jonas JB, Keeffe J, Kempen JH, Leasher J, Limburg H, Naidoo K, Pesudovs K, Silvester A, Stevens GA, Tahhan N, Wong TY, Taylor HR; Vision Loss Expert Group of the Global Burden of Disease Study
Lancet Glob Health 2017 Dec;5(12):e1221-e1234. Epub 2017 Oct 11 doi: 10.1016/S2214-109X(17)30393-5. PMID: 29032195

Supplemental Content

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