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Effusion

MedGen UID:
8557
Concept ID:
C0013687
Pathologic Function
Synonym: Free fluid
SNOMED CT: Effusion (41699000); Free fluid (41699000)

Definition

A collection of fluid in a body cavity, which may be the result of a non-neoplastic disorder (e.g. heart failure) or a tumor (e.g. carcinoma of the lung). [from NCI]

Professional guidelines

PubMed

Gayen S
Am J Med 2022 Oct;135(10):1188-1192. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.017. PMID: 35576996
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article
Harmes KM, Blackwood RA, Burrows HL, Cooke JM, Harrison RV, Passamani PP
Am Fam Physician 2013 Oct 1;88(7):435-40. PMID: 24134083

Recent clinical studies

Etiology

Sorino C, Mondoni M, Lococo F, Marchetti G, Feller-Kopman D
Respir Med 2022 Jan;191:106706. Epub 2021 Nov 26 doi: 10.1016/j.rmed.2021.106706. PMID: 34896966
Vakamudi S, Ho N, Cremer PC
Prog Cardiovasc Dis 2017 Jan-Feb;59(4):380-388. Epub 2017 Jan 4 doi: 10.1016/j.pcad.2016.12.009. PMID: 28062268
Ferreiro L, San José ME, Valdés L
Arch Bronconeumol 2015 Dec;51(12):637-46. Epub 2015 Mar 26 doi: 10.1016/j.arbres.2015.01.009. PMID: 25820035
Refaat MM, Katz WE
Clin Cardiol 2011 Oct;34(10):593-8. Epub 2011 Sep 16 doi: 10.1002/clc.20936. PMID: 21928406Free PMC Article
Huggins JT, Doelken P
Clin Chest Med 2006 Jun;27(2):229-40. doi: 10.1016/j.ccm.2005.12.007. PMID: 16716815

Diagnosis

Shao RJ, Du MJ, Xie JT
Eur Rev Med Pharmacol Sci 2022 Dec;26(23):8771-8776. doi: 10.26355/eurrev_202212_30548. PMID: 36524495
Gayen S
Am J Med 2022 Oct;135(10):1188-1192. Epub 2022 May 14 doi: 10.1016/j.amjmed.2022.04.017. PMID: 35576996
Ferreiro L, Suárez-Antelo J, Álvarez-Dobaño JM, Toubes ME, Riveiro V, Valdés L
Can Respir J 2020;2020:2950751. Epub 2020 Sep 23 doi: 10.1155/2020/2950751. PMID: 33273991Free PMC Article
Jany B, Welte T
Dtsch Arztebl Int 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377. PMID: 31315808Free PMC Article
McGrath EE, Anderson PB
Am J Crit Care 2011 Mar;20(2):119-27; quiz 128. doi: 10.4037/ajcc2011685. PMID: 21362716

Therapy

Hoberman A, Preciado D, Paradise JL, Chi DH, Haralam M, Block SL, Kearney DH, Bhatnagar S, Muñiz Pujalt GB, Shope TR, Martin JM, Felten DE, Kurs-Lasky M, Liu H, Yahner K, Jeong JH, Cohen NL, Czervionke B, Nagg JP, Dohar JE, Shaikh N
N Engl J Med 2021 May 13;384(19):1789-1799. doi: 10.1056/NEJMoa2027278. PMID: 33979487Free PMC Article
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503
Imazio M, Gaita F, LeWinter M
JAMA 2015 Oct 13;314(14):1498-506. doi: 10.1001/jama.2015.12763. PMID: 26461998
Llewellyn A, Norman G, Harden M, Coatesworth A, Kimberling D, Schilder A, McDaid C
Health Technol Assess 2014 Jul;18(46):1-180, v-vi. doi: 10.3310/hta18460. PMID: 25029951Free PMC Article
McGrath EE, Anderson PB
Am J Crit Care 2011 Mar;20(2):119-27; quiz 128. doi: 10.4037/ajcc2011685. PMID: 21362716

Prognosis

Wang X, Lu Z, Luo Y, Cai J, Wei J, Liu A, Zeng Z
Medicine (Baltimore) 2022 Feb 11;101(6):e28785. doi: 10.1097/MD.0000000000028785. PMID: 35147108Free PMC Article
Simard T, Jung RG, Lehenbauer K, Piayda K, Pracoń R, Jackson GG, Flores-Umanzor E, Faroux L, Korsholm K, Chun JKR, Chen S, Maarse M, Montrella K, Chaker Z, Spoon JN, Pastormerlo LE, Meincke F, Sawant AC, Moldovan CM, Qintar M, Aktas MK, Branca L, Radinovic A, Ram P, El-Zein RS, Flautt T, Ding WY, Sayegh B, Benito-González T, Lee OH, Badejoko SO, Paitazoglou C, Karim N, Zaghloul AM, Agrawal H, Kaplan RM, Alli O, Ahmed A, Suradi HS, Knight BP, Alla VM, Panaich SS, Wong T, Bergmann MW, Chothia R, Kim JS, Pérez de Prado A, Bazaz R, Gupta D, Valderrabano M, Sanchez CE, El Chami MF, Mazzone P, Adamo M, Ling F, Wang DD, O'Neill W, Wojakowski W, Pershad A, Berti S, Spoon D, Kawsara A, Jabbour G, Boersma LVA, Schmidt B, Nielsen-Kudsk JE, Rodés-Cabau J, Freixa X, Ellis CR, Fauchier L, Demkow M, Sievert H, Main ML, Hibbert B, Holmes DR Jr, Alkhouli M
J Am Coll Cardiol 2021 Jul 27;78(4):297-313. doi: 10.1016/j.jacc.2021.04.098. PMID: 34294267
Grønberg BH, Killingberg KT, Fløtten Ø, Brustugun OT, Hornslien K, Madebo T, Langer SW, Schytte T, Nyman J, Risum S, Tsakonas G, Engleson J, Halvorsen TO
Lancet Oncol 2021 Mar;22(3):321-331. doi: 10.1016/S1470-2045(20)30742-7. PMID: 33662285
El-Battrawy I, Roterberg G, Liebe V, Ansari U, Lang S, Zhou X, Borggrefe M, Akin I
Clin Cardiol 2019 Oct;42(10):958-965. Epub 2019 Aug 22 doi: 10.1002/clc.23247. PMID: 31441080Free PMC Article
Dedhia K, Graham E, Park A
Clin Perinatol 2018 Dec;45(4):629-643. Epub 2018 Sep 24 doi: 10.1016/j.clp.2018.07.004. PMID: 30396409

Clinical prediction guides

Spencer KT, Flachskampf FA
JACC Cardiovasc Imaging 2019 Jul;12(7 Pt 1):1243-1253. doi: 10.1016/j.jcmg.2018.12.036. PMID: 31272607
Picano E, Scali MC, Ciampi Q, Lichtenstein D
JACC Cardiovasc Imaging 2018 Nov;11(11):1692-1705. doi: 10.1016/j.jcmg.2018.06.023. PMID: 30409330
Refaat MM, Katz WE
Clin Cardiol 2011 Oct;34(10):593-8. Epub 2011 Sep 16 doi: 10.1002/clc.20936. PMID: 21928406Free PMC Article
Onusko E
Am Fam Physician 2004 Nov 1;70(9):1713-20. PMID: 15554489
Peterfy CG, Guermazi A, Zaim S, Tirman PF, Miaux Y, White D, Kothari M, Lu Y, Fye K, Zhao S, Genant HK
Osteoarthritis Cartilage 2004 Mar;12(3):177-90. doi: 10.1016/j.joca.2003.11.003. PMID: 14972335

Recent systematic reviews

Dainese P, Wyngaert KV, De Mits S, Wittoek R, Van Ginckel A, Calders P
Osteoarthritis Cartilage 2022 Apr;30(4):516-534. Epub 2021 Dec 27 doi: 10.1016/j.joca.2021.12.003. PMID: 34968719
Tsheten T, Clements ACA, Gray DJ, Adhikary RK, Furuya-Kanamori L, Wangdi K
Infect Dis Poverty 2021 Oct 9;10(1):123. doi: 10.1186/s40249-021-00908-2. PMID: 34627388Free PMC Article
Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA
Am J Respir Crit Care Med 2018 Oct 1;198(7):839-849. doi: 10.1164/rccm.201807-1415ST. PMID: 30272503
Imazio M, Gaita F, LeWinter M
JAMA 2015 Oct 13;314(14):1498-506. doi: 10.1001/jama.2015.12763. PMID: 26461998
McGrath EE, Anderson PB
Am J Crit Care 2011 Mar;20(2):119-27; quiz 128. doi: 10.4037/ajcc2011685. PMID: 21362716

Supplemental Content

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