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Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis

MedGen UID:
855737
Concept ID:
C3890733
Disease or Syndrome
Synonyms: Juvenile idiopathic rheumatoid factor-positive polyarthritis; juvenile idiopathic rheumatoid factor-positive polyarthritis; Juvenile polyarthritis with rheumatoid factor; polyarthritis with rheumatoid factor; Polyarticular JIA, RF+; polyarticular JIA, RF+; Polyarticular Juvenile Idiopathic Arthritis, RF+; polyarticular juvenile idiopathic arthritis, RF+; Polyarticular Juvenile Idiopathic Arthritis, Rheumatoid Factor Positive; polyarticular juvenile idiopathic arthritis, rheumatoid Factor Positive; Rheumatoid factor-positive polyarticular JIA; rheumatoid factor-positive polyarticular JIA; rheumatoid factor-positive polyarticular juvenile idiopathic arthritis
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
Concept ID:
CN307042
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
 
Monarch Initiative: MONDO:0019435
Orphanet: ORPHA85435

Definition

A rare form of juvenile idiopathic arthritis characterized by distal and symmetrical polyarthritis (more than 5 joints) with presence of rheumatoid factor and possible evolution towards the appearance of erosions and joint destruction. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRheumatoid factor-positive polyarticular juvenile idiopathic arthritis

Professional guidelines

PubMed

Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:192-197. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.055. PMID: 33845021Free PMC Article
Brunner HI, Wong R, Nys M, Kou TD, Dominique A, Martini A, Lovell DJ, Ruperto N; Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)
Paediatr Drugs 2020 Dec;22(6):653-672. Epub 2020 Oct 8 doi: 10.1007/s40272-020-00422-2. PMID: 33029724
Martini A, Ravelli A, Avcin T, Beresford MW, Burgos-Vargas R, Cuttica R, Ilowite NT, Khubchandani R, Laxer RM, Lovell DJ, Petty RE, Wallace CA, Wulffraat NM, Pistorio A, Ruperto N; Pediatric Rheumatology International Trials Organization (PRINTO)
J Rheumatol 2019 Feb;46(2):190-197. Epub 2018 Oct 1 doi: 10.3899/jrheum.180168. PMID: 30275259

Recent clinical studies

Etiology

Hinks A, Marion MC, Cobb J, Comeau ME, Sudman M, Ainsworth HC, Bowes J; Juvenile Idiopathic Arthritis Consortium for Immunochip, Becker ML, Bohnsack JF, Haas JP, Lovell DJ, Mellins ED, Nelson JL, Nordal E, Punaro M, Reed AM, Rose CD, Rosenberg AM, Rygg M, Smith SL, Stevens AM, Videm V, Wallace CA, Wedderburn LR, Yarwood A, Yeung RSM, Langefeld CD, Thompson SD, Thomson W, Prahalad S
Arthritis Rheumatol 2018 Jun;70(6):957-962. Epub 2018 Apr 21 doi: 10.1002/art.40443. PMID: 29426059Free PMC Article

Diagnosis

Akça ÜK, Sökmen O, Bölek EÇ, Demir S, Kılıç L, Çevik IÜ, Bilginer Y
Turk J Pediatr 2021;63(3):522-526. doi: 10.24953/turkjped.2021.03.022. PMID: 34254500
Clarke SLN, Robertson L, Rice GI, Seabra L, Hilliard TN, Crow YJ, Ramanan AV
Pediatr Rheumatol Online J 2020 May 12;18(1):37. doi: 10.1186/s12969-020-00425-w. PMID: 32398023Free PMC Article
Shi L, Hu F, Xu C, Zhu H, Qie D, Yuan C, Tao Y, Liu H
Int J Rheum Dis 2018 May;21(5):1142-1145. Epub 2017 Mar 22 doi: 10.1111/1756-185X.13064. PMID: 28328098

Therapy

Clarke SLN, Robertson L, Rice GI, Seabra L, Hilliard TN, Crow YJ, Ramanan AV
Pediatr Rheumatol Online J 2020 May 12;18(1):37. doi: 10.1186/s12969-020-00425-w. PMID: 32398023Free PMC Article
Shi L, Hu F, Xu C, Zhu H, Qie D, Yuan C, Tao Y, Liu H
Int J Rheum Dis 2018 May;21(5):1142-1145. Epub 2017 Mar 22 doi: 10.1111/1756-185X.13064. PMID: 28328098
Nerome Y, Imanaka H, Nonaka Y, Takei S
Mod Rheumatol 2007;17(6):526-8. Epub 2007 Dec 20 doi: 10.1007/s10165-007-0634-3. PMID: 18084710

Prognosis

Hinks A, Marion MC, Cobb J, Comeau ME, Sudman M, Ainsworth HC, Bowes J; Juvenile Idiopathic Arthritis Consortium for Immunochip, Becker ML, Bohnsack JF, Haas JP, Lovell DJ, Mellins ED, Nelson JL, Nordal E, Punaro M, Reed AM, Rose CD, Rosenberg AM, Rygg M, Smith SL, Stevens AM, Videm V, Wallace CA, Wedderburn LR, Yarwood A, Yeung RSM, Langefeld CD, Thompson SD, Thomson W, Prahalad S
Arthritis Rheumatol 2018 Jun;70(6):957-962. Epub 2018 Apr 21 doi: 10.1002/art.40443. PMID: 29426059Free PMC Article

Clinical prediction guides

Hinks A, Marion MC, Cobb J, Comeau ME, Sudman M, Ainsworth HC, Bowes J; Juvenile Idiopathic Arthritis Consortium for Immunochip, Becker ML, Bohnsack JF, Haas JP, Lovell DJ, Mellins ED, Nelson JL, Nordal E, Punaro M, Reed AM, Rose CD, Rosenberg AM, Rygg M, Smith SL, Stevens AM, Videm V, Wallace CA, Wedderburn LR, Yarwood A, Yeung RSM, Langefeld CD, Thompson SD, Thomson W, Prahalad S
Arthritis Rheumatol 2018 Jun;70(6):957-962. Epub 2018 Apr 21 doi: 10.1002/art.40443. PMID: 29426059Free PMC Article

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