U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Juvenile Primary Fibromyalgia Syndrome

MedGen UID:
856247
•Concept ID:
C3896653
•
Disease or Syndrome

Definition

Chronic, diffuse, non-inflammatory musculoskeletal pain disorder associated with fatigue and sleep disturbance that can occur in childhood and adolescence. Tender points are not necessary to make the diagnosis, but if present may be less numerous than found in adults. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJuvenile Primary Fibromyalgia Syndrome

Professional guidelines

PubMed

Juvenile primary fibromyalgia syndrome: A Review- Treatment and Prognosis.
Coles ML, Uziel Y
Pediatr Rheumatol Online J 2021 May 18;19(1):74. doi: 10.1186/s12969-021-00529-x. PMID: 34006290Free PMC Article
Pediatric pain syndromes and management of pain in children and adolescents with rheumatic disease.
Anthony KK, Schanberg LE
Pediatr Clin North Am 2005 Apr;52(2):611-39, vii. doi: 10.1016/j.pcl.2005.01.003. PMID: 15820381
A review of biobehavioral research in juvenile primary fibromyalgia syndrome.
Kashikar-Zuck S, Graham TB, Huenefeld MD, Powers SW
Arthritis Care Res 2000 Dec;13(6):388-97. doi: 10.1002/1529-0131(200012)13:6<388::aid-art9>3.0.co;2-p. PMID: 14635315

Recent clinical studies

Etiology

Pain, functional disability, and their Association in Juvenile Fibromyalgia Compared to other pediatric rheumatic diseases.
Connelly M, Weiss JE; for the CARRA Registry Investigators
Pediatr Rheumatol Online J 2019 Nov 6;17(1):72. doi: 10.1186/s12969-019-0375-9. PMID: 31694655Free PMC Article
Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
Weiss JE, Schikler KN, Boneparth AD, Connelly M; CARRA Registry Investigators
Pediatr Rheumatol Online J 2019 Jul 26;17(1):51. doi: 10.1186/s12969-019-0356-z. PMID: 31349785Free PMC Article
Juvenile primary fibromyalgia syndrome in an inpatient adolescent psychiatric population.
Lommel K, Kapoor S, Bamford J, Melguizo MS, Martin C, Crofford L
Int J Adolesc Med Health 2009 Oct-Dec;21(4):571-9. doi: 10.1515/ijamh.2009.21.4.571. PMID: 20306769
Anxiety, mood, and behavioral disorders among pediatric patients with juvenile fibromyalgia syndrome.
Kashikar-Zuck S, Parkins IS, Graham TB, Lynch AM, Passo M, Johnston M, Schikler KN, Hashkes PJ, Banez G, Richards MM
Clin J Pain 2008 Sep;24(7):620-6. doi: 10.1097/AJP.0b013e31816d7d23. PMID: 18716501Free PMC Article
Juvenile primary fibromyalgia syndrome.
Anthony KK, Schanberg LE
Curr Rheumatol Rep 2001 Apr;3(2):165-71. doi: 10.1007/s11926-001-0012-7. PMID: 11286673

Diagnosis

Juvenile primary fibromyalgia syndrome: A Review- Treatment and Prognosis.
Coles ML, Uziel Y
Pediatr Rheumatol Online J 2021 May 18;19(1):74. doi: 10.1186/s12969-021-00529-x. PMID: 34006290Free PMC Article
Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis.
Coles ML, Weissmann R, Uziel Y
Pediatr Rheumatol Online J 2021 Mar 1;19(1):22. doi: 10.1186/s12969-021-00493-6. PMID: 33648522Free PMC Article
Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
Weiss JE, Schikler KN, Boneparth AD, Connelly M; CARRA Registry Investigators
Pediatr Rheumatol Online J 2019 Jul 26;17(1):51. doi: 10.1186/s12969-019-0356-z. PMID: 31349785Free PMC Article
Juvenile Fibromyalgia: Different from the Adult Chronic Pain Syndrome?
Kashikar-Zuck S, King C, Ting TV, Arnold LM
Curr Rheumatol Rep 2016 Apr;18(4):19. doi: 10.1007/s11926-016-0569-9. PMID: 26984803
Anxiety, mood, and behavioral disorders among pediatric patients with juvenile fibromyalgia syndrome.
Kashikar-Zuck S, Parkins IS, Graham TB, Lynch AM, Passo M, Johnston M, Schikler KN, Hashkes PJ, Banez G, Richards MM
Clin J Pain 2008 Sep;24(7):620-6. doi: 10.1097/AJP.0b013e31816d7d23. PMID: 18716501Free PMC Article

Therapy

Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
Weiss JE, Schikler KN, Boneparth AD, Connelly M; CARRA Registry Investigators
Pediatr Rheumatol Online J 2019 Jul 26;17(1):51. doi: 10.1186/s12969-019-0356-z. PMID: 31349785Free PMC Article
Efficacy of cognitive-behavioral intervention for juvenile primary fibromyalgia syndrome.
Kashikar-Zuck S, Swain NF, Jones BA, Graham TB
J Rheumatol 2005 Aug;32(8):1594-602. PMID: 16078340
Pediatric pain syndromes and management of pain in children and adolescents with rheumatic disease.
Anthony KK, Schanberg LE
Pediatr Clin North Am 2005 Apr;52(2):611-39, vii. doi: 10.1016/j.pcl.2005.01.003. PMID: 15820381
A review of biobehavioral research in juvenile primary fibromyalgia syndrome.
Kashikar-Zuck S, Graham TB, Huenefeld MD, Powers SW
Arthritis Care Res 2000 Dec;13(6):388-97. doi: 10.1002/1529-0131(200012)13:6<388::aid-art9>3.0.co;2-p. PMID: 14635315
Fibromyalgia in children; diagnosis and treatment.
Romano TJ
W V Med J 1991 Mar;87(3):112-4. PMID: 2031345

Prognosis

Juvenile primary fibromyalgia syndrome: A Review- Treatment and Prognosis.
Coles ML, Uziel Y
Pediatr Rheumatol Online J 2021 May 18;19(1):74. doi: 10.1186/s12969-021-00529-x. PMID: 34006290Free PMC Article
Juvenile primary Fibromyalgia Syndrome: epidemiology, etiology, pathogenesis, clinical manifestations and diagnosis.
Coles ML, Weissmann R, Uziel Y
Pediatr Rheumatol Online J 2021 Mar 1;19(1):22. doi: 10.1186/s12969-021-00493-6. PMID: 33648522Free PMC Article
Juvenile Fibromyalgia: Different from the Adult Chronic Pain Syndrome?
Kashikar-Zuck S, King C, Ting TV, Arnold LM
Curr Rheumatol Rep 2016 Apr;18(4):19. doi: 10.1007/s11926-016-0569-9. PMID: 26984803
Anxiety, mood, and behavioral disorders among pediatric patients with juvenile fibromyalgia syndrome.
Kashikar-Zuck S, Parkins IS, Graham TB, Lynch AM, Passo M, Johnston M, Schikler KN, Hashkes PJ, Banez G, Richards MM
Clin J Pain 2008 Sep;24(7):620-6. doi: 10.1097/AJP.0b013e31816d7d23. PMID: 18716501Free PMC Article
Juvenile primary fibromyalgia syndrome.
Anthony KK, Schanberg LE
Curr Rheumatol Rep 2001 Apr;3(2):165-71. doi: 10.1007/s11926-001-0012-7. PMID: 11286673

Clinical prediction guides

Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
Weiss JE, Schikler KN, Boneparth AD, Connelly M; CARRA Registry Investigators
Pediatr Rheumatol Online J 2019 Jul 26;17(1):51. doi: 10.1186/s12969-019-0356-z. PMID: 31349785Free PMC Article
Juvenile Fibromyalgia: Different from the Adult Chronic Pain Syndrome?
Kashikar-Zuck S, King C, Ting TV, Arnold LM
Curr Rheumatol Rep 2016 Apr;18(4):19. doi: 10.1007/s11926-016-0569-9. PMID: 26984803
Relationship between sleep and pain in adolescents with juvenile primary fibromyalgia syndrome.
Olsen MN, Sherry DD, Boyne K, McCue R, Gallagher PR, Brooks LJ
Sleep 2013 Apr 1;36(4):509-16. doi: 10.5665/sleep.2534. PMID: 23564998Free PMC Article
Juvenile primary fibromyalgia syndrome in an inpatient adolescent psychiatric population.
Lommel K, Kapoor S, Bamford J, Melguizo MS, Martin C, Crofford L
Int J Adolesc Med Health 2009 Oct-Dec;21(4):571-9. doi: 10.1515/ijamh.2009.21.4.571. PMID: 20306769
Juvenile primary fibromyalgia syndrome.
Anthony KK, Schanberg LE
Curr Rheumatol Rep 2001 Apr;3(2):165-71. doi: 10.1007/s11926-001-0012-7. PMID: 11286673

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...