Stage IIIC includes: For squamous cell carcinoma: (T4a, N1-2, M0, Any G, Tumor location: Any); (T4b, Any N, M0, Any G, Tumor location: Any); (Any T, N3, M0, Any G, Tumor location: Any). T4a: Resectable tumor invading pleura, pericardium, or diaphragm. T4b: Unresectable tumor invading other adjacent structures, such as aorta, vertebral body, trachea, etc. N1: Metastasis in 1-2 regional lymph nodes. N2: Metastasis in 3-6 regional lymph nodes. N3: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis. Tumor location: Location of the primary cancer site is defined by the position of the upper (proximal) edge of the tumor in the esophagus. For adenocarcinoma: (T4a, N1-2, M0, Any G); (T4b, Any N, M0, Any G); (Any T, N3, M0, Any G). T4a: Resectable tumor invading pleura, pericardium, or diaphragm. T4b: Unresectable tumor invading other adjacent structures, such as aorta, vertebral body, trachea, etc. N1: Metastasis in 1-2 regional lymph nodes. N2: Metastasis in 3-6 regional lymph nodes. N3: Metastasis in seven or more regional lymph nodes. M0: No distant metastasis. (AJCC 7th ed.) [from NCI]