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Malunion of Bone

MedGen UID:
858065
•Concept ID:
C3898471
•
Finding
Synonym: Malunion

Definition

Faulty healing of bone, resulting in improper anatomical alignment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalunion of Bone

Professional guidelines

PubMed

Distal radius fractures: an evidence-based approach to assessment and management.
Vaghela KR, Velazquez-Pimentel D, Ahluwalia AK, Choraria A, Hunter A
Br J Hosp Med (Lond) 2020 Jun 2;81(6):1-8. Epub 2020 Jun 12 doi: 10.12968/hmed.2020.0006. PMID: 32589543
Management of Distal Femur Fractures in Adults: An Overview of Options.
Gangavalli AK, Nwachuku CO
Orthop Clin North Am 2016 Jan;47(1):85-96. doi: 10.1016/j.ocl.2015.08.011. PMID: 26614924
Treatment of clavicle fractures: current concepts review.
van der Meijden OA, Gaskill TR, Millett PJ
J Shoulder Elbow Surg 2012 Mar;21(3):423-9. Epub 2011 Nov 6 doi: 10.1016/j.jse.2011.08.053. PMID: 22063756

Recent clinical studies

Etiology

Incidence, Costs and Predictors of Non-Union, Delayed Union and Mal-Union Following Long Bone Fracture.
Ekegren CL, Edwards ER, de Steiger R, Gabbe BJ
Int J Environ Res Public Health 2018 Dec 13;15(12) doi: 10.3390/ijerph15122845. PMID: 30551632Free PMC Article
The scaphoid.
Sendher R, Ladd AL
Orthop Clin North Am 2013 Jan;44(1):107-20. doi: 10.1016/j.ocl.2012.09.003. PMID: 23174330
Diabetic calcaneal fractures.
Sagray BA, Stapleton JJ, Zgonis T
Clin Podiatr Med Surg 2013 Jan;30(1):111-8. Epub 2012 Oct 11 doi: 10.1016/j.cpm.2012.09.001. PMID: 23164444
Examination under anesthetic for occult pelvic ring instability.
Sagi HC, Coniglione FM, Stanford JH
J Orthop Trauma 2011 Sep;25(9):529-36. doi: 10.1097/BOT.0b013e31822b02ae. PMID: 21857421
Nonoperative treatment compared with plate fixation of displaced midshaft clavicular fractures. A multicenter, randomized clinical trial.
Canadian Orthopaedic Trauma Society
J Bone Joint Surg Am 2007 Jan;89(1):1-10. doi: 10.2106/JBJS.F.00020. PMID: 17200303

Diagnosis

Pediatric Forearm Malunions.
Ray S, Manske MC
Hand Clin 2024 Feb;40(1):35-48. Epub 2023 Sep 11 doi: 10.1016/j.hcl.2023.08.016. PMID: 37979989
Malunion of the Tibia: A Systematic Review.
Patel I, Young J, Washington A, Vaidya R
Medicina (Kaunas) 2022 Mar 5;58(3) doi: 10.3390/medicina58030389. PMID: 35334565Free PMC Article
Incidence, Costs and Predictors of Non-Union, Delayed Union and Mal-Union Following Long Bone Fracture.
Ekegren CL, Edwards ER, de Steiger R, Gabbe BJ
Int J Environ Res Public Health 2018 Dec 13;15(12) doi: 10.3390/ijerph15122845. PMID: 30551632Free PMC Article
The scaphoid.
Sendher R, Ladd AL
Orthop Clin North Am 2013 Jan;44(1):107-20. doi: 10.1016/j.ocl.2012.09.003. PMID: 23174330
Examination under anesthetic for occult pelvic ring instability.
Sagi HC, Coniglione FM, Stanford JH
J Orthop Trauma 2011 Sep;25(9):529-36. doi: 10.1097/BOT.0b013e31822b02ae. PMID: 21857421

Therapy

Revision of the Malaligned Ankle Arthrodesis.
Reeves CL, Shane AM, Sahli H, Togher C
Clin Podiatr Med Surg 2020 Jul;37(3):475-487. Epub 2020 May 11 doi: 10.1016/j.cpm.2020.03.003. PMID: 32471613
Bone Graft Options in Upper-Extremity Surgery.
Klifto CS, Gandi SD, Sapienza A
J Hand Surg Am 2018 Aug;43(8):755-761.e2. Epub 2018 Jul 3 doi: 10.1016/j.jhsa.2018.03.055. PMID: 29980395
Nonunions and malunions of the pelvis.
Tripathy SK, Goyal T, Sen RK
Eur J Trauma Emerg Surg 2015 Aug;41(4):335-42. Epub 2014 Nov 4 doi: 10.1007/s00068-014-0461-0. PMID: 26037993
The scaphoid.
Sendher R, Ladd AL
Orthop Clin North Am 2013 Jan;44(1):107-20. doi: 10.1016/j.ocl.2012.09.003. PMID: 23174330
Nonoperative treatment compared with plate fixation of displaced midshaft clavicular fractures. A multicenter, randomized clinical trial.
Canadian Orthopaedic Trauma Society
J Bone Joint Surg Am 2007 Jan;89(1):1-10. doi: 10.2106/JBJS.F.00020. PMID: 17200303

Prognosis

Distal Radius Malunion.
Katt B, Seigerman D, Lutsky K, Beredjiklian P
J Hand Surg Am 2020 May;45(5):433-442. Epub 2020 Mar 24 doi: 10.1016/j.jhsa.2020.02.008. PMID: 32220492
Incidence, Costs and Predictors of Non-Union, Delayed Union and Mal-Union Following Long Bone Fracture.
Ekegren CL, Edwards ER, de Steiger R, Gabbe BJ
Int J Environ Res Public Health 2018 Dec 13;15(12) doi: 10.3390/ijerph15122845. PMID: 30551632Free PMC Article
Nonunions and malunions of the pelvis.
Tripathy SK, Goyal T, Sen RK
Eur J Trauma Emerg Surg 2015 Aug;41(4):335-42. Epub 2014 Nov 4 doi: 10.1007/s00068-014-0461-0. PMID: 26037993
Treatment of clavicle fractures: current concepts review.
van der Meijden OA, Gaskill TR, Millett PJ
J Shoulder Elbow Surg 2012 Mar;21(3):423-9. Epub 2011 Nov 6 doi: 10.1016/j.jse.2011.08.053. PMID: 22063756
Tibiocalcaneal arthrodesis.
Mann RA, Chou LB
Foot Ankle Int 1995 Jul;16(7):401-5. doi: 10.1177/107110079501600704. PMID: 7550952

Clinical prediction guides

Double-level fixator-assisted nailing (DL-FAN).
Chaudhary MM, Lakhani PH
Bone Joint J 2019 Feb;101-B(2):178-188. doi: 10.1302/0301-620X.101B2.BJJ-2018-0622.R1. PMID: 30700124
Incidence, Costs and Predictors of Non-Union, Delayed Union and Mal-Union Following Long Bone Fracture.
Ekegren CL, Edwards ER, de Steiger R, Gabbe BJ
Int J Environ Res Public Health 2018 Dec 13;15(12) doi: 10.3390/ijerph15122845. PMID: 30551632Free PMC Article
Fractures of the clavicle.
Khan LA, Bradnock TJ, Scott C, Robinson CM
J Bone Joint Surg Am 2009 Feb;91(2):447-60. doi: 10.2106/JBJS.H.00034. PMID: 19181992
Nonoperative treatment compared with plate fixation of displaced midshaft clavicular fractures. A multicenter, randomized clinical trial.
Canadian Orthopaedic Trauma Society
J Bone Joint Surg Am 2007 Jan;89(1):1-10. doi: 10.2106/JBJS.F.00020. PMID: 17200303
Triple arthrodesis.
Fortin PT, Walling AK
Clin Orthop Relat Res 1999 Aug;(365):91-9. doi: 10.1097/00003086-199908000-00012. PMID: 10627691

Recent systematic reviews

Pelvic Malunion: A Systematic Review, Dichotomy of Definitions and Treatment.
Stine S, Washington A, Sen RK, Nasr K, Vaidya R
Medicina (Kaunas) 2022 Aug 14;58(8) doi: 10.3390/medicina58081098. PMID: 36013565Free PMC Article
Malunion of the Tibia: A Systematic Review.
Patel I, Young J, Washington A, Vaidya R
Medicina (Kaunas) 2022 Mar 5;58(3) doi: 10.3390/medicina58030389. PMID: 35334565Free PMC Article
Malunited calcaneal fracture: the role and technique of osteotomy-a systematic review.
Guan X, Xiang D, Hu Y, Jiang G, Yu B, Wang B
Int Orthop 2021 Oct;45(10):2663-2678. Epub 2021 Jul 9 doi: 10.1007/s00264-021-05130-1. PMID: 34240235
Paediatric lateral condyle fractures: a systematic review.
Tan SHS, Dartnell J, Lim AKS, Hui JH
Arch Orthop Trauma Surg 2018 Jun;138(6):809-817. Epub 2018 Mar 24 doi: 10.1007/s00402-018-2920-2. PMID: 29574555
Nonunions and malunions of the pelvis.
Tripathy SK, Goyal T, Sen RK
Eur J Trauma Emerg Surg 2015 Aug;41(4):335-42. Epub 2014 Nov 4 doi: 10.1007/s00068-014-0461-0. PMID: 26037993

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