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Insufficient Breast Milk Syndrome

MedGen UID:
858342
•Concept ID:
C3898748
•
Disease or Syndrome

Definition

Failure to thrive due to poor intake by the infant, inadequate feeding schedule or insufficient maternal production of breast milk. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInsufficient Breast Milk Syndrome

Professional guidelines

PubMed

Nutritional management of cow's milk allergy in children: An update.
Dupont C, Chouraqui JP, Linglart A, Bocquet A, Darmaun D, Feillet F, Frelut ML, Girardet JP, Hankard R, Rozé JC, Simeoni U, Briend A; Committee on Nutrition of the French Society of Pediatrics
Arch Pediatr 2018 Apr;25(3):236-243. Epub 2018 Mar 22 doi: 10.1016/j.arcped.2018.01.007. PMID: 29576253
Probiotics and prebiotics in prevention and treatment of diseases in infants and children.
Vandenplas Y, Veereman-Wauters G, De Greef E, Peeters S, Casteels A, Mahler T, Devreker T, Hauser B
J Pediatr (Rio J) 2011 Jul-Aug;87(4):292-300. Epub 2011 Jul 8 doi: 10.2223/JPED.2103. PMID: 21769417
Medical management of short gut syndrome.
Bhatia J, Gates A, Parish A
J Perinatol 2010 Oct;30 Suppl:S2-5. doi: 10.1038/jp.2010.100. PMID: 20877403

Recent clinical studies

Etiology

Is There an Association Between Breast Hypoplasia and Breastfeeding Outcomes? A Systematic Review.
Kam RL, Amir LH, Cullinane M
Breastfeed Med 2021 Aug;16(8):594-602. Epub 2021 Apr 23 doi: 10.1089/bfm.2021.0032. PMID: 33891493
Infant milk-feeding practices and cardiovascular disease outcomes in offspring: a systematic review.
Güngör D, Nadaud P, LaPergola CC, Dreibelbis C, Wong YP, Terry N, Abrams SA, Beker L, Jacobovits T, Järvinen KM, Nommsen-Rivers LA, O'Brien KO, Oken E, Pérez-Escamilla R, Ziegler EE, Spahn JM
Am J Clin Nutr 2019 Mar 1;109(Suppl_7):800S-816S. doi: 10.1093/ajcn/nqy332. PMID: 30982872Free PMC Article
Sudden infant death syndrome and abnormal metabolism of thiamin.
Lonsdale D
Med Hypotheses 2015 Dec;85(6):922-6. Epub 2015 Sep 14 doi: 10.1016/j.mehy.2015.09.009. PMID: 26455416
Use of domperidone as a galactagogue drug: a systematic review of the benefit-risk ratio.
Paul C, Zénut M, Dorut A, Coudoré MA, Vein J, Cardot JM, Balayssac D
J Hum Lact 2015 Feb;31(1):57-63. Epub 2014 Dec 4 doi: 10.1177/0890334414561265. PMID: 25475074
Down syndrome and breastfeeding.
Pisacane A, Toscano E, Pirri I, Continisio P, Andria G, Zoli B, Strisciuglio P, Concolino D, Piccione M, Lo Giudice C, Vicari S
Acta Paediatr 2003 Dec;92(12):1479-81. doi: 10.1080/08035250310007024. PMID: 14971802

Diagnosis

Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review.
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC
Ultrasound Obstet Gynecol 2020 Jul;56(1):15-27. doi: 10.1002/uog.22088. PMID: 32430957Free PMC Article
Domperidone for increasing breast milk volume in mothers expressing breast milk for their preterm infants: a systematic review and meta-analysis.
Grzeskowiak LE, Smithers LG, Amir LH, Grivell RM
BJOG 2018 Oct;125(11):1371-1378. Epub 2018 Mar 27 doi: 10.1111/1471-0528.15177. PMID: 29469929
Down syndrome and breastfeeding.
Pisacane A, Toscano E, Pirri I, Continisio P, Andria G, Zoli B, Strisciuglio P, Concolino D, Piccione M, Lo Giudice C, Vicari S
Acta Paediatr 2003 Dec;92(12):1479-81. doi: 10.1080/08035250310007024. PMID: 14971802
Cholesterol and development: the RSH ("Smith-Lemli-Opitz") syndrome and related conditions.
Opitz JM, Gilbert-Barness E, Ackerman J, Lowichik A
Pediatr Pathol Mol Med 2002 Mar-Apr;21(2):153-81. doi: 10.1080/15227950252852078. PMID: 11942534
Breastfeeding and breast milk jaundice.
Leung AK, Sauve RS
J R Soc Health 1989 Dec;109(6):213-7. doi: 10.1177/146642408910900615. PMID: 2513410

Therapy

Neurotoxic effects of combined exposures to aluminum and mercury in early life (infancy).
Dórea JG
Environ Res 2020 Sep;188:109734. Epub 2020 Jun 8 doi: 10.1016/j.envres.2020.109734. PMID: 32544722
Domperidone for increasing breast milk volume in mothers expressing breast milk for their preterm infants: a systematic review and meta-analysis.
Grzeskowiak LE, Smithers LG, Amir LH, Grivell RM
BJOG 2018 Oct;125(11):1371-1378. Epub 2018 Mar 27 doi: 10.1111/1471-0528.15177. PMID: 29469929
Use of domperidone as a galactagogue drug: a systematic review of the benefit-risk ratio.
Paul C, Zénut M, Dorut A, Coudoré MA, Vein J, Cardot JM, Balayssac D
J Hum Lact 2015 Feb;31(1):57-63. Epub 2014 Dec 4 doi: 10.1177/0890334414561265. PMID: 25475074
Probiotics and prebiotics in prevention and treatment of diseases in infants and children.
Vandenplas Y, Veereman-Wauters G, De Greef E, Peeters S, Casteels A, Mahler T, Devreker T, Hauser B
J Pediatr (Rio J) 2011 Jul-Aug;87(4):292-300. Epub 2011 Jul 8 doi: 10.2223/JPED.2103. PMID: 21769417
Vitamin K in parenteral nutrition.
Shearer MJ
Gastroenterology 2009 Nov;137(5 Suppl):S105-18. doi: 10.1053/j.gastro.2009.08.046. PMID: 19874942

Prognosis

Measures of Maternal Metabolic Health as Predictors of Severely Low Milk Production.
Nommsen-Rivers LA, Wagner EA, Roznowski DM, Riddle SW, Ward LP, Thompson A
Breastfeed Med 2022 Jul;17(7):566-576. Epub 2022 Apr 26 doi: 10.1089/bfm.2021.0292. PMID: 35475660Free PMC Article
Neurotoxic effects of combined exposures to aluminum and mercury in early life (infancy).
Dórea JG
Environ Res 2020 Sep;188:109734. Epub 2020 Jun 8 doi: 10.1016/j.envres.2020.109734. PMID: 32544722
Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review.
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC
Ultrasound Obstet Gynecol 2020 Jul;56(1):15-27. doi: 10.1002/uog.22088. PMID: 32430957Free PMC Article
Effect of the method of breast feeding on breast engorgement, mastitis and infantile colic.
Evans K, Evans R, Simmer K
Acta Paediatr 1995 Aug;84(8):849-52. doi: 10.1111/j.1651-2227.1995.tb13777.x. PMID: 7488804
Potential indicators of insufficient milk supply syndrome.
Hill PD, Aldag J
Res Nurs Health 1991 Feb;14(1):11-9. doi: 10.1002/nur.4770140104. PMID: 2017578

Clinical prediction guides

Measures of Maternal Metabolic Health as Predictors of Severely Low Milk Production.
Nommsen-Rivers LA, Wagner EA, Roznowski DM, Riddle SW, Ward LP, Thompson A
Breastfeed Med 2022 Jul;17(7):566-576. Epub 2022 Apr 26 doi: 10.1089/bfm.2021.0292. PMID: 35475660Free PMC Article
Neurotoxic effects of combined exposures to aluminum and mercury in early life (infancy).
Dórea JG
Environ Res 2020 Sep;188:109734. Epub 2020 Jun 8 doi: 10.1016/j.envres.2020.109734. PMID: 32544722
Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review.
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC
Ultrasound Obstet Gynecol 2020 Jul;56(1):15-27. doi: 10.1002/uog.22088. PMID: 32430957Free PMC Article
Use of domperidone as a galactagogue drug: a systematic review of the benefit-risk ratio.
Paul C, Zénut M, Dorut A, Coudoré MA, Vein J, Cardot JM, Balayssac D
J Hum Lact 2015 Feb;31(1):57-63. Epub 2014 Dec 4 doi: 10.1177/0890334414561265. PMID: 25475074
Potential indicators of insufficient milk supply syndrome.
Hill PD, Aldag J
Res Nurs Health 1991 Feb;14(1):11-9. doi: 10.1002/nur.4770140104. PMID: 2017578

Recent systematic reviews

Is There an Association Between Breast Hypoplasia and Breastfeeding Outcomes? A Systematic Review.
Kam RL, Amir LH, Cullinane M
Breastfeed Med 2021 Aug;16(8):594-602. Epub 2021 Apr 23 doi: 10.1089/bfm.2021.0032. PMID: 33891493
Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review.
Juan J, Gil MM, Rong Z, Zhang Y, Yang H, Poon LC
Ultrasound Obstet Gynecol 2020 Jul;56(1):15-27. doi: 10.1002/uog.22088. PMID: 32430957Free PMC Article
Infant milk-feeding practices and cardiovascular disease outcomes in offspring: a systematic review.
Güngör D, Nadaud P, LaPergola CC, Dreibelbis C, Wong YP, Terry N, Abrams SA, Beker L, Jacobovits T, Järvinen KM, Nommsen-Rivers LA, O'Brien KO, Oken E, Pérez-Escamilla R, Ziegler EE, Spahn JM
Am J Clin Nutr 2019 Mar 1;109(Suppl_7):800S-816S. doi: 10.1093/ajcn/nqy332. PMID: 30982872Free PMC Article
Domperidone for increasing breast milk volume in mothers expressing breast milk for their preterm infants: a systematic review and meta-analysis.
Grzeskowiak LE, Smithers LG, Amir LH, Grivell RM
BJOG 2018 Oct;125(11):1371-1378. Epub 2018 Mar 27 doi: 10.1111/1471-0528.15177. PMID: 29469929
Use of domperidone as a galactagogue drug: a systematic review of the benefit-risk ratio.
Paul C, Zénut M, Dorut A, Coudoré MA, Vein J, Cardot JM, Balayssac D
J Hum Lact 2015 Feb;31(1):57-63. Epub 2014 Dec 4 doi: 10.1177/0890334414561265. PMID: 25475074

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