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Decreased Best Corrected Visual Acuity

MedGen UID:
858998
•Concept ID:
C3899404
•
Finding
Synonym: Decreased best corrected visual acuity

Definition

Diminished clarity of vision despite optimal optical correction (glasses and/or contacts). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased Best Corrected Visual Acuity

Professional guidelines

PubMed

Long-Term Outcomes of High-Dose Conbercept Treatment for Myopic Choroidal Neovascularization and Idiopathic Choroidal Neovascularization.
Zhu W, Hao Y, Yuan Z, Huang C, Liu J, Ma Y
Ophthalmic Res 2023;66(1):636-644. Epub 2023 Feb 6 doi: 10.1159/000529342. PMID: 36746135
Anisometropic amblyopia: A review of functional and structural changes and treatment.
Meng C, Zhang Y, Wang S
Eur J Ophthalmol 2023 Jul;33(4):1529-1535. Epub 2022 Nov 29 doi: 10.1177/11206721221143164. PMID: 36448184
COMPARISON OF RESOLUTION OF VITREOMACULAR TRACTION AFTER OCRIPLASMIN TREATMENT OR VITRECTOMY.
Scholz P, Sitnilska V, Hess J, Becker M, Michels S, Fauser S
Retina 2019 Jan;39(1):180-185. doi: 10.1097/IAE.0000000000001926. PMID: 29135889

Recent clinical studies

Etiology

X-Linked Retinoschisis: Deep Phenotyping and Genetic Characterization.
Georgiou M, Finocchio L, Fujinami K, Fujinami-Yokokawa Y, Virgili G, Mahroo OA, Webster AR, Michaelides M
Ophthalmology 2022 May;129(5):542-551. Epub 2021 Nov 23 doi: 10.1016/j.ophtha.2021.11.019. PMID: 34822951
Expanding the clinical phenotype in patients with disease causing variants associated with atypical Usher syndrome.
Igelman AD, Ku C, da Palma MM, Georgiou M, Schiff ER, Lam BL, Sankila EM, Ahn J, Pyers L, Vincent A, Ferraz Sallum JM, Zein WM, Oh JK, Maldonado RS, Ryu J, Tsang SH, Gorin MB, Webster AR, Michaelides M, Yang P, Pennesi ME
Ophthalmic Genet 2021 Dec;42(6):664-673. Epub 2021 Jul 5 doi: 10.1080/13816810.2021.1946704. PMID: 34223797Free PMC Article
Deep Phenotyping of PDE6C-Associated Achromatopsia.
Georgiou M, Robson AG, Singh N, Pontikos N, Kane T, Hirji N, Ripamonti C, Rotsos T, Dubra A, Kalitzeos A, Webster AR, Carroll J, Michaelides M
Invest Ophthalmol Vis Sci 2019 Dec 2;60(15):5112-5123. doi: 10.1167/iovs.19-27761. PMID: 31826238Free PMC Article
CORRELATION BETWEEN OUTER RETINAL THICKENING AND RETINAL FUNCTION IMPAIRMENT IN PATIENTS WITH IDIOPATHIC EPIRETINAL MEMBRANES.
Cacciamani A, Cosimi P, Di Nicola M, Di Martino G, Ripandelli G, Scarinci F
Retina 2019 Feb;39(2):331-338. doi: 10.1097/IAE.0000000000001971. PMID: 29190229
Early clinical and subclinical visual evoked potential and Humphrey's visual field defects in cryptococcal meningitis.
Moodley A, Rae W, Bhigjee A, Connolly C, Devparsad N, Michowicz A, Harrison T, Loyse A
PLoS One 2012;7(12):e52895. Epub 2012 Dec 21 doi: 10.1371/journal.pone.0052895. PMID: 23285220Free PMC Article

Diagnosis

Long-Term Outcomes of High-Dose Conbercept Treatment for Myopic Choroidal Neovascularization and Idiopathic Choroidal Neovascularization.
Zhu W, Hao Y, Yuan Z, Huang C, Liu J, Ma Y
Ophthalmic Res 2023;66(1):636-644. Epub 2023 Feb 6 doi: 10.1159/000529342. PMID: 36746135
X-Linked Retinoschisis: Deep Phenotyping and Genetic Characterization.
Georgiou M, Finocchio L, Fujinami K, Fujinami-Yokokawa Y, Virgili G, Mahroo OA, Webster AR, Michaelides M
Ophthalmology 2022 May;129(5):542-551. Epub 2021 Nov 23 doi: 10.1016/j.ophtha.2021.11.019. PMID: 34822951
Pinhole does not increase screening accuracy of detecting decreased best corrected visual acuity in schoolchildren.
Chen W, Fu J, Sun A, Li L, Sun Y, Meng Z
BMC Ophthalmol 2021 Dec 2;21(1):416. doi: 10.1186/s12886-021-02150-8. PMID: 34856946Free PMC Article
Expanding the clinical phenotype in patients with disease causing variants associated with atypical Usher syndrome.
Igelman AD, Ku C, da Palma MM, Georgiou M, Schiff ER, Lam BL, Sankila EM, Ahn J, Pyers L, Vincent A, Ferraz Sallum JM, Zein WM, Oh JK, Maldonado RS, Ryu J, Tsang SH, Gorin MB, Webster AR, Michaelides M, Yang P, Pennesi ME
Ophthalmic Genet 2021 Dec;42(6):664-673. Epub 2021 Jul 5 doi: 10.1080/13816810.2021.1946704. PMID: 34223797Free PMC Article
Deep Phenotyping of PDE6C-Associated Achromatopsia.
Georgiou M, Robson AG, Singh N, Pontikos N, Kane T, Hirji N, Ripamonti C, Rotsos T, Dubra A, Kalitzeos A, Webster AR, Carroll J, Michaelides M
Invest Ophthalmol Vis Sci 2019 Dec 2;60(15):5112-5123. doi: 10.1167/iovs.19-27761. PMID: 31826238Free PMC Article

Therapy

Long-Term Outcomes of High-Dose Conbercept Treatment for Myopic Choroidal Neovascularization and Idiopathic Choroidal Neovascularization.
Zhu W, Hao Y, Yuan Z, Huang C, Liu J, Ma Y
Ophthalmic Res 2023;66(1):636-644. Epub 2023 Feb 6 doi: 10.1159/000529342. PMID: 36746135
Pinhole does not increase screening accuracy of detecting decreased best corrected visual acuity in schoolchildren.
Chen W, Fu J, Sun A, Li L, Sun Y, Meng Z
BMC Ophthalmol 2021 Dec 2;21(1):416. doi: 10.1186/s12886-021-02150-8. PMID: 34856946Free PMC Article
In Vivo Confocal Microscopy Demonstrates Increased Immune Cell Densities in Corneal Graft Rejection Correlating With Signs and Symptoms.
Chirapapaisan C, Abbouda A, Jamali A, Müller RT, Cavalcanti BM, Colon C, Witkin D, Sahin A, Dana R, Cruzat A, Hamrah P
Am J Ophthalmol 2019 Jul;203:26-36. Epub 2019 Feb 18 doi: 10.1016/j.ajo.2019.02.013. PMID: 30790547
Simultaneous Implantation of an Ahmed and Baerveldt Glaucoma Drainage Device for Uncontrolled Intraocular Pressure in Advanced Glaucoma.
Rao VS, Christenbury J, Lee P, Allingham R, Herndon L, Challa P
J Glaucoma 2017 Feb;26(2):101-106. doi: 10.1097/IJG.0000000000000531. PMID: 27599171
Opacification of piggyback IOLs associated with an amorphous material attached to interlenticular surfaces.
Werner L, Shugar JK, Apple DJ, Pandey SK, Escobar-Gomez M, Visessook N, Evans BB
J Cataract Refract Surg 2000 Nov;26(11):1612-9. doi: 10.1016/s0886-3350(00)00485-5. PMID: 11084268

Prognosis

X-Linked Retinoschisis: Deep Phenotyping and Genetic Characterization.
Georgiou M, Finocchio L, Fujinami K, Fujinami-Yokokawa Y, Virgili G, Mahroo OA, Webster AR, Michaelides M
Ophthalmology 2022 May;129(5):542-551. Epub 2021 Nov 23 doi: 10.1016/j.ophtha.2021.11.019. PMID: 34822951
PDE6C: Novel Mutations, Atypical Phenotype, and Differences Among Children and Adults.
Daich Varela M, Ullah E, Yousaf S, Brooks BP, Hufnagel RB, Huryn LA
Invest Ophthalmol Vis Sci 2020 Oct 1;61(12):1. doi: 10.1167/iovs.61.12.1. PMID: 33001157Free PMC Article
Deep Phenotyping of PDE6C-Associated Achromatopsia.
Georgiou M, Robson AG, Singh N, Pontikos N, Kane T, Hirji N, Ripamonti C, Rotsos T, Dubra A, Kalitzeos A, Webster AR, Carroll J, Michaelides M
Invest Ophthalmol Vis Sci 2019 Dec 2;60(15):5112-5123. doi: 10.1167/iovs.19-27761. PMID: 31826238Free PMC Article
In Vivo Confocal Microscopy Demonstrates Increased Immune Cell Densities in Corneal Graft Rejection Correlating With Signs and Symptoms.
Chirapapaisan C, Abbouda A, Jamali A, Müller RT, Cavalcanti BM, Colon C, Witkin D, Sahin A, Dana R, Cruzat A, Hamrah P
Am J Ophthalmol 2019 Jul;203:26-36. Epub 2019 Feb 18 doi: 10.1016/j.ajo.2019.02.013. PMID: 30790547
CORRELATION BETWEEN OUTER RETINAL THICKENING AND RETINAL FUNCTION IMPAIRMENT IN PATIENTS WITH IDIOPATHIC EPIRETINAL MEMBRANES.
Cacciamani A, Cosimi P, Di Nicola M, Di Martino G, Ripandelli G, Scarinci F
Retina 2019 Feb;39(2):331-338. doi: 10.1097/IAE.0000000000001971. PMID: 29190229

Clinical prediction guides

Long-Term Outcomes of High-Dose Conbercept Treatment for Myopic Choroidal Neovascularization and Idiopathic Choroidal Neovascularization.
Zhu W, Hao Y, Yuan Z, Huang C, Liu J, Ma Y
Ophthalmic Res 2023;66(1):636-644. Epub 2023 Feb 6 doi: 10.1159/000529342. PMID: 36746135
X-Linked Retinoschisis: Deep Phenotyping and Genetic Characterization.
Georgiou M, Finocchio L, Fujinami K, Fujinami-Yokokawa Y, Virgili G, Mahroo OA, Webster AR, Michaelides M
Ophthalmology 2022 May;129(5):542-551. Epub 2021 Nov 23 doi: 10.1016/j.ophtha.2021.11.019. PMID: 34822951
In Vivo Confocal Microscopy Demonstrates Increased Immune Cell Densities in Corneal Graft Rejection Correlating With Signs and Symptoms.
Chirapapaisan C, Abbouda A, Jamali A, Müller RT, Cavalcanti BM, Colon C, Witkin D, Sahin A, Dana R, Cruzat A, Hamrah P
Am J Ophthalmol 2019 Jul;203:26-36. Epub 2019 Feb 18 doi: 10.1016/j.ajo.2019.02.013. PMID: 30790547
Prevalence of macular abnormalities assessed by optical coherence tomography in patients with Usher syndrome.
Testa F, Melillo P, Rossi S, Marcelli V, de Benedictis A, Colucci R, Gallo B, Brunetti-Pierri R, Donati S, Azzolini C, Marciano E, Simonelli F
Ophthalmic Genet 2018 Jan-Feb;39(1):17-21. Epub 2017 Jul 13 doi: 10.1080/13816810.2017.1329445. PMID: 28704163
Retinal Dysfunction in Patients with Congenital Fibrosis of the Extraocular Muscles Type 2.
Khan AO, Almutlaq M, Oystreck DT, Engle EC, Abu-Amero K, Bosley T
Ophthalmic Genet 2016 Jun;37(2):130-6. Epub 2014 Jun 18 doi: 10.3109/13816810.2014.926942. PMID: 24940936Free PMC Article

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