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Cerebral Hemorrhage Related to Birth

MedGen UID:
859286
•Concept ID:
C3899692
•
Finding

Definition

Intracranial bleeding in the tissue of the cerebrum of a newborn infant occurring during labor and/or delivery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCerebral Hemorrhage Related to Birth

Professional guidelines

PubMed

Genetic testing in individuals with cerebral palsy.
May HJ, Fasheun JA, Bain JM, Baugh EH, Bier LE, Revah-Politi A; New York Presbyterian Hospital/Columbia University Irving Medical Center Genomics Team, Roye DP Jr, Goldstein DB, Carmel JB
Dev Med Child Neurol 2021 Dec;63(12):1448-1455. Epub 2021 Jun 10 doi: 10.1111/dmcn.14948. PMID: 34114234Free PMC Article
Consensus statement on abusive head trauma in infants and young children.
Choudhary AK, Servaes S, Slovis TL, Palusci VJ, Hedlund GL, Narang SK, Moreno JA, Dias MS, Christian CW, Nelson MD Jr, Silvera VM, Palasis S, Raissaki M, Rossi A, Offiah AC
Pediatr Radiol 2018 Aug;48(8):1048-1065. Epub 2018 May 23 doi: 10.1007/s00247-018-4149-1. PMID: 29796797
Cerebral blood flow studies in the diagnosis and management of intrauterine growth restriction.
Hernandez-Andrade E, Stampalija T, Figueras F
Curr Opin Obstet Gynecol 2013 Apr;25(2):138-44. doi: 10.1097/GCO.0b013e32835e0e9c. PMID: 23354073

Recent clinical studies

Etiology

Ultrasound imaging of preterm brain injury: fundamentals and updates.
Hwang M, Tierradentro-García LO, Hussaini SH, Cajigas-Loyola SC, Kaplan SL, Otero HJ, Bellah RD
Pediatr Radiol 2022 Apr;52(4):817-836. Epub 2021 Oct 14 doi: 10.1007/s00247-021-05191-9. PMID: 34648071
The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications.
Jung E, Romero R, Yeo L, Diaz-Primera R, Marin-Concha J, Para R, Lopez AM, Pacora P, Gomez-Lopez N, Yoon BH, Kim CJ, Berry SM, Hsu CD
Semin Fetal Neonatal Med 2020 Aug;25(4):101146. Epub 2020 Oct 23 doi: 10.1016/j.siny.2020.101146. PMID: 33164775Free PMC Article
The Impact of Prematurity on Social and Emotional Development.
Leon Hernandez A
Clin Perinatol 2018 Sep;45(3):547-555. Epub 2018 Jul 2 doi: 10.1016/j.clp.2018.05.010. PMID: 30144854
Chorioamnionitis and prematurity: a critical review.
Martinelli P, Sarno L, Maruotti GM, Paludetto R
J Matern Fetal Neonatal Med 2012 Oct;25 Suppl 4:29-31. doi: 10.3109/14767058.2012.714981. PMID: 22958008
Chorioamnionitis and cerebral palsy: a meta-analysis.
Shatrov JG, Birch SCM, Lam LT, Quinlivan JA, McIntyre S, Mendz GL
Obstet Gynecol 2010 Aug;116(2 Pt 1):387-392. doi: 10.1097/AOG.0b013e3181e90046. PMID: 20664400

Diagnosis

The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications.
Jung E, Romero R, Yeo L, Diaz-Primera R, Marin-Concha J, Para R, Lopez AM, Pacora P, Gomez-Lopez N, Yoon BH, Kim CJ, Berry SM, Hsu CD
Semin Fetal Neonatal Med 2020 Aug;25(4):101146. Epub 2020 Oct 23 doi: 10.1016/j.siny.2020.101146. PMID: 33164775Free PMC Article
The Impact of Prematurity on Social and Emotional Development.
Leon Hernandez A
Clin Perinatol 2018 Sep;45(3):547-555. Epub 2018 Jul 2 doi: 10.1016/j.clp.2018.05.010. PMID: 30144854
Consensus statement on abusive head trauma in infants and young children.
Choudhary AK, Servaes S, Slovis TL, Palusci VJ, Hedlund GL, Narang SK, Moreno JA, Dias MS, Christian CW, Nelson MD Jr, Silvera VM, Palasis S, Raissaki M, Rossi A, Offiah AC
Pediatr Radiol 2018 Aug;48(8):1048-1065. Epub 2018 May 23 doi: 10.1007/s00247-018-4149-1. PMID: 29796797
Circulatory Management Focusing on Preventing Intraventricular Hemorrhage and Pulmonary Hemorrhage in Preterm Infants.
Su BH, Lin HY, Huang FK, Tsai ML, Huang YT
Pediatr Neonatol 2016 Dec;57(6):453-462. Epub 2016 Feb 4 doi: 10.1016/j.pedneo.2016.01.001. PMID: 26993561
Cerebral blood flow studies in the diagnosis and management of intrauterine growth restriction.
Hernandez-Andrade E, Stampalija T, Figueras F
Curr Opin Obstet Gynecol 2013 Apr;25(2):138-44. doi: 10.1097/GCO.0b013e32835e0e9c. PMID: 23354073

Therapy

Intraventricular hemorrhage prediction in premature neonates in the era of hemodynamics monitoring: a prospective cohort study.
Farag MM, Gouda MH, Almohsen AMA, Khalifa MA
Eur J Pediatr 2022 Dec;181(12):4067-4077. Epub 2022 Sep 28 doi: 10.1007/s00431-022-04630-5. PMID: 36171508Free PMC Article
ELBW infants receive inadvertent sodium load above the recommended intake.
Eibensteiner F, Laml-Wallner G, Thanhaeuser M, Ristl R, Ely S, Jilma B, Berger A, Haiden N
Pediatr Res 2020 Sep;88(3):412-420. Epub 2020 Apr 9 doi: 10.1038/s41390-020-0867-9. PMID: 32272484
Pentoxifylline in preterm neonates: a systematic review.
Harris E, Schulzke SM, Patole SK
Paediatr Drugs 2010 Oct 1;12(5):301-11. doi: 10.2165/11532600-000000000-00000. PMID: 20799759
Current concepts and controversies in the use of vitamin K.
Thorp JA, Gaston L, Caspers DR, Pal ML
Drugs 1995 Mar;49(3):376-87. doi: 10.2165/00003495-199549030-00005. PMID: 7774512
Surfactant therapy and intracranial hemorrhage: review of the literature and results of new analyses.
Gunkel JH, Banks PL
Pediatrics 1993 Dec;92(6):775-86. PMID: 8233736

Prognosis

Incidence and Time Trends of Pregnancy-Related Stroke Between 2010 and 2018: The Nationwide CONCEPTION Study.
Martin A, Lailler G, Béjot Y, Gabet A, Grave C, Regnault N, Chatignoux E, Moutengou E, Deneux-Tharaux C, Kretz S, Mounier-Vehier C, Tsatsaris V, Plu-Bureau G, Blacher J, Olié V
Neurology 2022 Oct 11;99(15):e1598-e1608. Epub 2022 Aug 29 doi: 10.1212/WNL.0000000000200944. PMID: 36038274Free PMC Article
Long-term outcomes of very-low-birth-weight and low-birth-weight preterm newborns with neonatal seizures: A single-center perspective.
Schüssler SC, Schmidt M, Deiters L, Candova A, Fahlbusch FB, Trollmann R
Eur J Paediatr Neurol 2022 Jan;36:137-142. Epub 2021 Dec 22 doi: 10.1016/j.ejpn.2021.12.013. PMID: 34973622
The Effect of Flow-Related Aneurysms on Hemorrhagic Risk of Intracranial Arteriovenous Malformations.
Hung AL, Yang W, Jiang B, Garzon-Muvdi T, Caplan JM, Colby GP, Coon AL, Tamargo RJ, Huang J
Neurosurgery 2019 Oct 1;85(4):466-475. doi: 10.1093/neuros/nyy360. PMID: 30107479
Intracranial hemorrhage in term neonates.
Hong HS, Lee JY
Childs Nerv Syst 2018 Jun;34(6):1135-1143. Epub 2018 Apr 10 doi: 10.1007/s00381-018-3788-8. PMID: 29637304Free PMC Article
The value of autopsy in determining the cause of failure to respond to resuscitation at birth.
Squier W, Cowan FM
Semin Neonatol 2004 Aug;9(4):331-45. doi: 10.1016/j.siny.2004.01.003. PMID: 15251149

Clinical prediction guides

Incidence and Time Trends of Pregnancy-Related Stroke Between 2010 and 2018: The Nationwide CONCEPTION Study.
Martin A, Lailler G, Béjot Y, Gabet A, Grave C, Regnault N, Chatignoux E, Moutengou E, Deneux-Tharaux C, Kretz S, Mounier-Vehier C, Tsatsaris V, Plu-Bureau G, Blacher J, Olié V
Neurology 2022 Oct 11;99(15):e1598-e1608. Epub 2022 Aug 29 doi: 10.1212/WNL.0000000000200944. PMID: 36038274Free PMC Article
Long-term outcomes of very-low-birth-weight and low-birth-weight preterm newborns with neonatal seizures: A single-center perspective.
Schüssler SC, Schmidt M, Deiters L, Candova A, Fahlbusch FB, Trollmann R
Eur J Paediatr Neurol 2022 Jan;36:137-142. Epub 2021 Dec 22 doi: 10.1016/j.ejpn.2021.12.013. PMID: 34973622
The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications.
Jung E, Romero R, Yeo L, Diaz-Primera R, Marin-Concha J, Para R, Lopez AM, Pacora P, Gomez-Lopez N, Yoon BH, Kim CJ, Berry SM, Hsu CD
Semin Fetal Neonatal Med 2020 Aug;25(4):101146. Epub 2020 Oct 23 doi: 10.1016/j.siny.2020.101146. PMID: 33164775Free PMC Article
Intracranial hemorrhage in term neonates.
Hong HS, Lee JY
Childs Nerv Syst 2018 Jun;34(6):1135-1143. Epub 2018 Apr 10 doi: 10.1007/s00381-018-3788-8. PMID: 29637304Free PMC Article
The value of autopsy in determining the cause of failure to respond to resuscitation at birth.
Squier W, Cowan FM
Semin Neonatol 2004 Aug;9(4):331-45. doi: 10.1016/j.siny.2004.01.003. PMID: 15251149

Recent systematic reviews

Immediate vs delayed cord clamping in preterm infants: A systematic review and meta-analysis.
Li J, Yang S, Yang F, Wu J, Xiong F
Int J Clin Pract 2021 Nov;75(11):e14709. Epub 2021 Sep 1 doi: 10.1111/ijcp.14709. PMID: 34370357
Global incidence of intraventricular hemorrhage among extremely preterm infants: a systematic literature review.
Siffel C, Kistler KD, Sarda SP
J Perinat Med 2021 Nov 25;49(9):1017-1026. Epub 2021 Mar 19 doi: 10.1515/jpm-2020-0331. PMID: 33735943
Antenatal infection and intraventricular hemorrhage in preterm infants: A meta-analysis.
Huang J, Meng J, Choonara I, Xiong T, Wang Y, Wang H, Qu Y, Mu D
Medicine (Baltimore) 2019 Aug;98(31):e16665. doi: 10.1097/MD.0000000000016665. PMID: 31374040Free PMC Article
Pentoxifylline in preterm neonates: a systematic review.
Harris E, Schulzke SM, Patole SK
Paediatr Drugs 2010 Oct 1;12(5):301-11. doi: 10.2165/11532600-000000000-00000. PMID: 20799759
Chorioamnionitis and cerebral palsy: a meta-analysis.
Shatrov JG, Birch SCM, Lam LT, Quinlivan JA, McIntyre S, Mendz GL
Obstet Gynecol 2010 Aug;116(2 Pt 1):387-392. doi: 10.1097/AOG.0b013e3181e90046. PMID: 20664400

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